Yuchong Yang,Tanya K Ronson,Paula C P Teeuwen et al.
Yuchong Yang et al.
Interwoven molecular structures underpin the functions of many biomolecules, yet synthesizing artificial topologically complex structures in high yield remains challenging. Here we describe a streamlined, high-yield one-pot synthesis of kno...
Qing Zhang,Nils J Flodén,Yongliang Zhang et al.
Qing Zhang et al.
The development of a general strategy for stereospecific construction of every type of glycosidic linkage remains a much sought-after yet unrealized goal. Such a strategy would be particularly useful in the context of complex glycan synthes...
Synthesis and reactivity of nitrogen-containing strained cyclic 1,2,3-trienes [0.03%]
含氮环应变1,2,3-三烯的合成与反应性研究
Dominick C Witkowski,Daniel W Turner,Ana S Bulger et al.
Dominick C Witkowski et al.
Cyclic 1,2,3-trienes are a class of intermediates that confine a functional group with a preferred linear geometry into a ring. When the ring is sufficiently small, the 1,2,3-triene geometry becomes bent, leading to substantial strain and h...
Luca McDermott,Zach G Walters,Allison M Clark et al.
Luca McDermott et al.
π-bonds are typically associated with well-defined arrangements of atoms. However, when the arrangement of atoms associated with these bonds becomes geometrically distorted, heightened reactivity is seen, enabling a wide range of transform...
Carbon isotopic labelling of carboxylic acids enabled by organic photoredox-catalysed cyanation [0.03%]
有机光红氧化催化的氰化反应实现羧酸的碳同位素标记
Zhengbo Zhu,Xuedan Wu,Gerald Thomas Bida et al.
Zhengbo Zhu et al.
The application of molecular imaging has advanced personalized medicine and generated a profound impact on patient care. Positron emission tomography and magnetic resonance imaging are among the most widely used imaging modalities, often re...
Nanocrystal synthesis with alkoxy reagents for dispersion in polar and non-polar solvents [0.03%]
用于在极性溶剂和非极性溶剂中分散的醇氧试剂纳米晶合成
Suresh Sarkar,Opeyemi H Arogundade,Yuxiao Cui et al.
Suresh Sarkar et al.
Applications of colloidal nanocrystals in polar solvents often require nanocrystals synthesized in non-polar solvents. However, solvent transfer processes are problematic and deteriorate nanocrystal quality. Here we report syntheses of nano...
Interdiffusion-enhanced cation exchange for HgSe and HgCdSe nanocrystals with infrared bandgaps [0.03%]
基于阳离子交换的HgSe和HgCdSe红外纳米晶材料生长机制研究
Wonseok Lee,Andrew M Smith
Wonseok Lee
Colloidal semiconductor nanocrystals based on CdSe have been precisely optimized for photonic applications in the visible spectrum, with modern products exhibiting structural uniformity, near 100% quantum yield and linewidths narrower than ...
Synthesis of chiral difluoromethyl cyclopropanes through desymmetric difluoromethylation of cyclopropenes enabled by enantioselective copper catalysis [0.03%]
手性双氟甲基环丙烷通过旋光选择性铜催化环丙烯的不对称双氟甲基化合成
Decai Ding,Su Chen,Lingfeng Yin et al.
Decai Ding et al.
The incorporation of enantioenriched difluoromethyl cyclopropane (DFC) groups into drug candidates has garnered increasing attention in the pharmaceutical industry due to the unique ability of the DFC groups to serve as conformationally rig...
Palladium-catalysed methylene C(sp 3)-H lactamization and cycloamination enabled by chlorinated pyridine-pyridone ligands [0.03%]
氯化吡啶-吡啶酮配体促进的钯催化亚甲基C（sp3）-H内酰胺化和环氨化反应
Hau Sun Sam Chan,Yilin Lu,Jin-Quan Yu
Hau Sun Sam Chan
Recent developments of bifunctional ligands have rapidly advanced palladium-catalyzed C(sp 3)-H activation reactions directed by native carboxylic acids. However, using this approach in inter or intramolecular C(sp 3)-H amination reactions ...
Synthesis of alkenyl boronates through stereoselective vinylene homologation of organoboronates [0.03%]
有机硼酸酯乙烯基同系物的立体选择性合成
Miao Chen,Thomas H Tugwell,Peng Liu et al.
Miao Chen et al.
Matteson homologation of organoboronates is an attractive approach for constructing aliphatic carbon chains via iterative insertion of carbenoids. However, the corresponding homologation that can introduce alkene moieties to molecular backb...