Phloretin inhibits ferroptosis by restoring the antioxidant capacity of bovine adipose and muscle cells via the AMPK-PPAR signaling pathway [0.03%]
芍药素通过AMPK-PPAR信号途径恢复牛脂肪和肌肉细胞的抗氧化能力从而抑制铁死亡
Jie Li,Enhui Jiang,Mengyang Zhang et al.
Jie Li et al.
Ferroptosis has been increasingly implicated in adipose and muscle dysfunction, systemic metabolic disturbances, and several diseases in livestock, which necessitates effective and side-effect-free inhibition strategies. Phloretin, a dihydr...
Engineered elicitin protein enhances Phytophthora resistance in plants by dual immune induction and pathogen inhibition [0.03%]
一种工程激发蛋白通过双重免疫诱导和抑制病原体而增强植物卵菌抗性
Zhengpeng Li,Yong Pei,Hao Zhou et al.
Zhengpeng Li et al.
Phytophthora pathogens are devastating agricultural threats that cannot synthesize sterols and must scavenge them from host plants. This study exploits their sterol auxotrophy by engineering a dual-function elicitin protein, SOJ5V84F, for e...
OsNTL2 confers rice osmotic stress resilience through coordinated transcriptional regulation of the ASC-GSH redox cycle and cell wall biosynthesis [0.03%]
OsNTL2通过协调ASC-GSH氧化还原循环和细胞壁生物合成的转录调控赋予水稻渗透胁迫抗性
Heng Zhou,Xiaoyun Ma,Jianping Yang et al.
Heng Zhou et al.
Drought, high salinity, and low temperatures impose osmotic stress, hindering water uptake and severely limiting plant growth and crop productivity. Osmotic stress not only perturbs cellular osmotic homeostasis but also disrupts multiple me...
Apple replant disease: unraveling the fungal enigma hidden in the rhizosphere [0.03%]
苹果再植病害：根球中隐藏的真菌谜团解析
Ziqing Ma,Yiwei Jia,Zhiquan Mao et al.
Ziqing Ma et al.
The occurrence of apple replant disease (ARD) is closely related to the increase of soil pathogenic fungi abundance. However, the relationship between ARD and fungal community structure remains poorly understood. In this study, Illumina hig...
Nontoxic mesoporous silica nanoparticles protect Physcomitrium patens against salt stress [0.03%]
无毒介孔二氧化硅纳米颗粒可保护苔类植物Physcomitrium patens免受盐胁迫侵害
Ying Zhou,Zhuo Yang,Jiaxue Li et al.
Ying Zhou et al.
Mosses play a crucial role in environmental protection, ecological preservation, and horticulture. While the effects of nanomaterials on angiosperms have been widely studied, their impact on bryophytes remains underexplored. In this study, ...
Choline attenuates NEFA-induced hepatic steatosis via GNMT regulation in hepatocytes [0.03%]
胆碱通过调节肝细胞中的GNMT来缓解NEFA诱导的肝脂肪变性疾病
Xueer Du,Lamei Wang,Yanfei Dai et al.
Xueer Du et al.
To elucidate the molecular mechanisms by which choline regulates hepatic lipid metabolism under negative energy balance conditions, we established non-esterified fatty acid (NEFA)-induced hepatic steatosis models in both calf primary hepato...
Exploring the mechanisms of desert plant adaptation to arid climates: a multi-omics analysis of dehydration and rehydration responses in Syntrichia caninervis [0.03%]
沙漠植物适应干旱环境的机制探索——Syntrichia caninervis干燥和复水响应的多组学分析
Qilin Yang,Huan Zhang,Fangliu Yin et al.
Qilin Yang et al.
Desert plants have evolved remarkable adaptations to survive in arid environments, where water scarcity and extreme temperatures pose significant challenges to life. The desert moss Syntrichia caninervis stands out as an exemplary model of ...
Impact of clothianidin exposure on the growth, metabolism, and neurological function of Penaeus vannamei [0.03%]
噻虫胺对凡 Nauplii 生长、代谢和神经功能的影响
Zhi Luo,Zhen-Fei Li,Zhi-Yu Lin et al.
Zhi Luo et al.
Clothianidin, a widely used neonicotinoid pesticide, poses potential ecological risks to aquatic ecosystems due to its unique mode of action and widespread environmental dispersal. This study investigates the toxic effects of clothianidin o...
Plant-pathogen interactions: making the case for multi-omics analysis of complex pathosystems [0.03%]
植物与病原物互作：复杂病害体系多组学分析的必要性
Sadegh Balotf,Richard Wilson,Roghayeh Hemmati et al.
Sadegh Balotf et al.
Understanding plant-pathogen interactions requires a systems-level perspective that single-omics approaches, such as genomics, transcriptomics, proteomics, or metabolomics alone, often fail to provide. While these methods are informative, t...
Seminal plasma exosomes improve the motility and mitochondrial function of goat spermatozoa during liquid storage by regulating oxidative phosphorylation [0.03%]
精浆外泌体通过调节氧化磷酸化改善冷冻保存过程中山羊精子的运动性和线粒体功能
Tengfei Liu,Mengmei Zhang,Xinkang Li et al.
Tengfei Liu et al.
Exosomes as bilayer membranous vesicles are abundant in seminal plasma and mediate intercellular communication by transferring active biomolecules. Numerous studies have revealed the involvement of exosomes in regulating various biological ...