A multivariate decomposition analysis of drivers of overweight and obesity among Ghanaian women [0.03%]
影响加纳女性超重和肥胖因素的多元分解分析
Joseph Prince Mensah,Robert Akparibo,Afua Atuobi-Yeboah et al.
Joseph Prince Mensah et al.
Background: Overweight and obesity are rising globally, with Ghana experiencing significant increases among women over the past two decades, raising public health concerns. This study aimed to identify and quantify the ke...
The role of social determinants in COVID-19 hospitalization disparities by migration status in Stockholm, Sweden. A population-based cohort study [0.03%]
迁移状态在瑞典斯德哥尔摩新冠肺炎住院差异中的社会决定因素作用的一项基于人群的队列研究
Yan Ma,Anders Ledberg,Siddartha Aradhya et al.
Yan Ma et al.
Background: Immigrants in Sweden, particularly those from low- and middle-income countries, had higher risks of COVID-19 mortality and morbidity compared to the Swedish-born. However, prior studies have not quantified the...
Digital twins support cross-modal and cross-centric classification of mild cognitive impairment [0.03%]
数字孪生支持的轻度认知障碍跨模式和跨视角分类
Lorenzo Gaetano Amato,Roberta Minino,Michael Lassi et al.
Lorenzo Gaetano Amato et al.
Background: Neural recordings capture crucial pathophysiological processes along the dementia continuum. However, cross-center variability in recording techniques and paradigms limit their generalizability and diagnostic ...
Natural history of simple and complex cysts in autosomal dominant polycystic kidney disease on MRI [0.03%]
autosomal显性多囊肾病患者单纯性和复杂性肾脏囊肿的自然史（MRI观察）
Zhongxiu Hu,Caden Li,Jon D Blumenfeld et al.
Zhongxiu Hu et al.
Background: Kidney volume, reflecting cumulative effects of many cysts, is an important prognostic biomarker for autosomal dominant polycystic kidney disease (ADPKD) but fails in many patients. Tracking individual cysts m...
Nalmefene and naltrexone reduce alcohol intake via selective efficacy in subpopulations distinguished by behavioral and blood-based biomarkers [0.03%]
通过行为和血液生物标志物区分的亚群的选择性有效性减少酒精摄入量 Nälmefene 和 naltrexone 的作用机制
Zahra Z Farahbakhsh,Alex R Brown,Suzanne O Nolan et al.
Zahra Z Farahbakhsh et al.
Background: The relative efficacies of nalmefene versus naltrexone for alcohol use disorder is the subject of intense and ongoing debate. The two pan-opioid receptor ligands differ primarily in actions at the kappa opioid...
Association of chronic disease risk and physical activity measured by wearable devices in the All of Us program [0.03%]
在美国全民项目中通过可穿戴设备测量慢性病风险与体力活动之间的关系
Yu Hou,Erjia Cui,Kelvin Lim et al.
Yu Hou et al.
Background: Physical activity plays an important role in preventing chronic diseases, but most studies rely on self-reported or short-term data that fail to capture habitual behavior. This study utilizes Fitbit data to in...
IdentifiHR predicts homologous recombination deficiency in high-grade serous ovarian carcinoma using gene expression [0.03%]
基于基因表达预测高级别浆液性卵巢癌中同源重组缺陷的IdentifiHR模型
Ashley L Weir,Samuel C Lee,Mengbo Li et al.
Ashley L Weir et al.
Background: Approximately half of all high-grade serous ovarian carcinomas (HGSCs) have a therapeutically targetable defect in homologous recombination (HR) DNA repair. While there are genomic and transcriptomic methods, ...
Probing intratumoral metabolic compartmentalisation in a patient with fumarate hydratase-deficient renal cancer using clinical hyperpolarised 13C-MRI and mass spectrometry imaging [0.03%]
利用临床超极化¹³C-MRI和质谱成像检测富马酸水合酶缺陷型肾癌患者的肿瘤内代谢隔室现象
Ines Horvat-Menih,Ruth Casey,James Denholm et al.
Ines Horvat-Menih et al.
Background: Fumarate hydratase-deficient renal cell carcinoma (FHd-RCC) is a rare and aggressive renal cancer subtype characterised by increased fumarate accumulation and upregulated lactate production. Renal tumours demo...
Linea Schmidt,Susanne Ibing,Florian Borchert et al.
Linea Schmidt et al.
Background: Real-world studies based on electronic health records often require manual chart review to derive patients' clinical phenotypes, a labor-intensive task with limited scalability. Here, we developed and compared...
Volumetric non-invasive cardiac mapping for accessible global arrhythmia characterization [0.03%]
无创体积心脏映射实现心律失常的全球表征
Jorge Vicente-Puig,Judit Chamorro-Servent,Ernesto Zacur et al.
Jorge Vicente-Puig et al.
Background: Cardiac arrhythmias are a major cause of morbidity and mortality increasing the risk of stroke, heart failure, and sudden cardiac death. Imageless electrocardiographic Imaging has emerged as an accessible non-...