Nutrition in early life interacts with genetic risk to influence preadult behaviour in the Raine Study [0.03%]
早年营养通过基因风险影响赖恩研究项目受试者成年前的行为表型
Lars Meinertz Byg,Carol A Wang,John Attia et al.
Lars Meinertz Byg et al.
Background: Early life nutrition is associated with child behaviour; however, the interplay with genetic vulnerability is understudied. We hypothesised that psychiatric genetic risk interacted with early nutrition to pred...
Global Disease Burden of Traumatic Joint Dislocation from 1990 to 2021 and its prediction to 2045 [0.03%]
1990年至2021年全球创伤性关节脱位疾病负担及2045年前预测值
Jingtao Huang,Haoxian Tang,Jiayou Chen et al.
Jingtao Huang et al.
Background: Traumatic joint dislocations of the hip, knee, and shoulder (DOH, DOK, and DOS) significantly impact global healthcare. This study assesses the global burden of joint dislocations using the Global Burden of Di...
Editorial Expression of Concern: SARS-CoV-2 detection using a nanobody-functionalized voltammetric device [0.03%]
表达关切声明：使用纳米抗体功能化伏安仪检测SARS-CoV-2
Quentin Pagneux,Alain Roussel,Hiba Saada et al.
Quentin Pagneux et al.
Cardiovascular measures from abdominal MRI provide insights into abdominal vessel genetic architecture [0.03%]
腹部磁共振成像的心血管测量可为腹主动脉遗传结构提供洞见
Nicolas Basty,Elena P Sorokin,Marjola Thanaj et al.
Nicolas Basty et al.
Background: Cardiovascular disease remains a major source of morbidity and mortality, and population imaging studies have yielded insights into disease etiology and risk. ...
Cerebrospinal fluid cfDNA-based molecular assessment of resection extent and prognosis in glioma [0.03%]
基于脑脊液游离DNA的胶质瘤切除范围和预后分子评估
Jun Wu,Zhiqiang Liu,Tianxiang Huang et al.
Jun Wu et al.
Background: Gliomas, the most common brain tumors, present significant challenges in treatment, particularly glioblastoma multiforme (GBM), due to their infiltrative nature and difficulty in achieving gross total resectio...
Prediction of outcome from spatial Protein profiling of triple-negative breast cancers [0.03%]
三阴性乳腺癌空间蛋白质组学预测模型用于指导精准治疗
Ali Foroughi Pour,Te-Chia Wu,Javad Noorbakhsh et al.
Ali Foroughi Pour et al.
Background: In tumors, reciprocal spatial interactions between immune cells, their mediators, the extracellular matrix, and mutated neoplastic cells impact all aspects of treatment resistance. The operational mechanisms o...
The clinical significance of the Mediterranean fever gene MEFV variants in Castleman disease [0.03%]
MEFV基因变异在卡斯特曼病的临床意义
Yumo Du,Shuangfeng Xie,Zhen Dai et al.
Yumo Du et al.
Background: Idiopathic Multicentric Castleman Disease, Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis, Organomegaly (iMCD-TAFRO) is a rare cytokine storm syndrome with high mortality. Pathogenesis of Castleman dise...
Selective blockade of latent TGF-β1 activation suppresses tissue fibrosis with good safety [0.03%]
选择性抑制潜伏TGF-β1激活可安全控制组织纤维化
Masakazu Kanamori,Izumi Sato,Christine Xing&#x;er Koo et al.
Masakazu Kanamori et al.
Background: Fibrosis is a hallmark of organ failure observed after chronic epithelial injury and inflammation. The transforming growth factor beta (TGF-β) is the master regulator of fibrogenesis, so blockade of the TGF-...
HIV persistence in tissues on dolutegravir-based therapy is not associated with resistance mutations to dolutegravir [0.03%]
基于多替拉韦的治疗方案中组织中的HIV持续感染与对多替拉韦无耐药关系
Gilbert Mchantaf,Adeline Melard,Kévin Da Silva et al.
Gilbert Mchantaf et al.
Background: Relatively few studies have investigated HIV-1 persistence in tissues, especially in healthy people-living-with-HIV-1 (PLWH) on a successful antiretroviral regimen containing second generation integrase inhibi...
Ischemic brain infarcts, white matter hyperintensities, and cognitive impairment are increased in patients with Atrial Fibrillation [0.03%]
房颤患者脑梗死、白质病变和认知功能障碍增加
Philipp Krisai,Stefanie Aeschbacher,Michael Coslovsky et al.
Philipp Krisai et al.
Background: The interrelationships between atrial fibrillation (AF), brain lesions and cognitive function are poorly understood. We aimed to investigate the relationship of AF with brain lesions and cognition. ...