Challenges in implementing cultural adaptations of digital health interventions [0.03%]
数字健康干预措施在文化适应实施中的挑战
Vasileios Nittas,Paola Daniore,Sarah J Chavez et al.
Vasileios Nittas et al.
Differences in the access and use of digital health interventions are driven by culture, in addition to economic and physical factors. To avoid the systematic exclusion of traditionally underserved cultural groups, creating inclusive digita...
Tethered spinal cord tension assessed via ultrasound elastography in computational and intraoperative human studies [0.03%]
通过计算和人体实验中超声弹性成像对牵拉性脊髓圆锥张力的评估
Max J Kerensky,Abhijit Paul,Denis Routkevitch et al.
Max J Kerensky et al.
Background: Tension in the spinal cord is a trademark of tethered cord syndrome. Unfortunately, existing tests cannot quantify tension across the bulk of the cord, making the diagnostic evaluation of stretch ambiguous. A ...
Computational pathology identifies immune-mediated collagen disruption to predict clinical outcomes in gynecologic malignancies [0.03%]
计算病理学识别免疫介导的胶原蛋白破坏以预测妇科恶性肿瘤的临床结果
Arpit Aggarwal,Sirvan Khalighi,Deepak Babu et al.
Arpit Aggarwal et al.
Background: The role of immune cells in collagen degradation within the tumor microenvironment (TME) is unclear. Immune cells, particularly tumor-infiltrating lymphocytes (TILs), are known to alter the extracellular matri...
Substantial but spatially heterogeneous progress in male circumcision for HIV prevention in South Africa [0.03%]
南非在男性包皮环切术防治艾滋病方面取得了显著但地区差异较大的进展
Matthew L Thomas,Khangelani Zuma,Dayanund Loykissoonlal et al.
Matthew L Thomas et al.
Background: Voluntary medical male circumcision (VMMC) reduces the risk of male HIV acquisition by 60%. Programmes to provide VMMCs for HIV prevention have been introduced in sub-Saharan African countries with high HIV bu...
Large-scale data reveal disparate associations between leisure time physical activity patterns and mental health [0.03%]
大规模数据揭示闲暇时间体育活动模式与心理健康之间的不同关联
Ying Zhou,Chenshuang Li,Wei Wang et al.
Ying Zhou et al.
Background: Leisure time physical activity (LTPA) is known to be associated with a lower risk for mental health burden, while whether the underlying mechanisms vary across populations is unknown. We aimed to explore the d...
Noninvasive measurement of 13Carbon turnover for evaluation of porcine renal grafts during ex vivo machine perfusion [0.03%]
体外机器灌注期间对猪肾移植的非侵入性测量13碳转化率评估
Thomas Minor,Laura Malkus,Hristo Zlatev et al.
Thomas Minor et al.
Background: Kidney transplantation suffers from a shortage of donor organs. Despite this, a lot of grafts are discarded due to inadequate quality. As many kidneys are afflicted by transient filtration failure early after ...
Bin Zhang,Lu Zhang,Qiuying Chen et al.
Bin Zhang et al.
Artificial intelligence (AI) has unparalleled potential to unlock useful information from real-world data to innovate trial design. Here, we discuss how AI can be used to optimize clinical trial design and potentially boost the success rate...
Perceptions of the seriousness of major public health problems during the COVID-19 pandemic in seven middle-income countries [0.03%]
七个中等收入国家在COVID-19大流行期间对主要公共卫生问题严重性的认识
Richard T Carson,Michael Hanemann,Gunnar Köhlin et al.
Richard T Carson et al.
Introduction: Public perception of the seriousness of the COVID-19 pandemic compared to six other major public health problems (alcoholism and drug use, HIV/AIDS, malaria, tuberculosis, lung cancer and respiratory disease...
Machine learning identifies risk factors associated with long-term sick leave following COVID-19 in Danish population [0.03%]
机器学习识别丹麦人群COVID-19后长期病假的风险因素
Kim Daniel Jakobsen,Elisabeth O&#x;Regan,Ingrid Bech Svalgaard et al.
Kim Daniel Jakobsen et al.
Background: Post COVID-19 condition (PCC) can lead to considerable morbidity, including prolonged sick-leave. Identifying risk groups is important for informing interventions. We investigated heterogeneity in the effect o...
Large-scale deep learning analysis to identify adult patients at risk for combined and common variable immunodeficiencies [0.03%]
利用大规模深度学习分析识别成人联合免疫缺陷和常见变异性免疫缺陷风险患者
Giorgos Papanastasiou,Guang Yang,Dimitris I Fotiadis et al.
Giorgos Papanastasiou et al.
Background: Primary immunodeficiency (PI) is a group of heterogeneous disorders resulting from immune system defects. Over 70% of PI is undiagnosed, leading to increased mortality, co-morbidity and healthcare costs. Among...