25-Hydroxyvitamin D3 metabolism modulates the effect of variable UV exposure on 25-hydroxyvitamin D3 plasma concentrations [0.03%]
25-羟基维生素D3代谢调节不同紫外线照射对25-羟基维生素D3血浆浓度的影响
Alexandra Scholze,Alexander Shinkov,Georgi S Slavov et al.
Alexandra Scholze et al.
Background: 25-hydroxyvitamin D3 (25(OH)D3) affects immune function, bone health, and reproduction. The precursor of 25(OH)D3, vitamin D3, is synthesized upon ultraviolet (UV) radiation exposure, the levels of which vary....
Geospatial analysis of the impact of Cameroonian Anglophone Crisis conflict intensity on antenatal care utilisation [0.03%]
基于空间分析的研究：喀麦隆安格鲁危机冲突强度对产前护理利用的影响研究
Abigail Ngwang,Kerry Lm Wong,Aduragbemi Banke-Thomas
Abigail Ngwang
Background: Adequate antenatal care (ANC) is often unrealised in sub-Saharan Africa (SSA). This is exemplified in the Cameroonian Anglophone Crisis, an ongoing armed civil conflict. Conflict intensity varies nationally, c...
A deep learning model for the diagnosis of gastric neuroendocrine carcinoma [0.03%]
用于胃神经内分泌癌诊断的深度学习模型
Tianchen Zhu,Zihan Zhao,Chao Wang et al.
Tianchen Zhu et al.
Background: Gastric neuroendocrine carcinoma (G-NEC) presents with clinical and pathological features that closely resemble those of gastric adenocarcinoma (GC), often complicating differential diagnosis. However, G-NEC i...
Early prediction of Alzheimer's disease using longitudinal electronic health records of US military veterans [0.03%]
基于美国退伍军人纵向电子健康记录的阿尔茨海默病早期预测研究
Rumeng Li,Dan Berlowitz,Jesse Mez et al.
Rumeng Li et al.
Background: Early prediction of Alzheimer's disease is important for timely intervention and treatment. We examine whether machine learning on longitudinal electronic health record notes can improve early prediction of Al...
Metabolism fluctuation coupling can track the progression of dementia and describe MST1 gene-related pathology [0.03%]
代谢波动耦合可以追踪痴呆的发展并描述MST1基因相关病理学特征
Jinhua Sheng,Ze Yang,Yang Wang et al.
Jinhua Sheng et al.
Background: Cognitive resilience refers to an individual's capacity to cope with brain aging and pathology and to delay cognitive decline, whereas existing techniques such as functional magnetic resonance imaging capture ...
Mendelian randomization study of GLP-1R effects on ovarian cancer subtypes mediated by metabolic factors [0.03%]
基于代谢因素的GLP-1R对卵巢癌亚型影响的孟德尔随机化研究
Jiajia Liu,Zhihe Chen,Qian Yang et al.
Jiajia Liu et al.
Background: Ovarian cancer is a major female reproductive health issue with heterogeneous biological features on its subtypes, which may require different therapeutic strategies. Glucagon-like peptide-1 receptor (GLP-1R) ...
Respiratory effort burden measured by mandibular jaw movements as a digital marker with clinical insights in obstructive sleep apnea [0.03%]
基于阻塞性睡眠呼吸暂停临床洞察的下颌运动呼吸努力负担量化数字化标志物研究
Jean-Benoît Martinot,Nhat-Nam Le-Dong,Didier Clause et al.
Jean-Benoît Martinot et al.
Background: The clinical symptoms of obstructive sleep apnea (OSA) are poorly correlated with disease severity based on the apnea-hypopnea index (AHI). The cumulative duration of respiratory effort assessed by mandibular ...
A matched case-control study on Escherichia coli factors contributing to sepsis and septic shock in bacteraemic patients [0.03%]
一项配对病例对照研究：菌血症患者的致感染性休克的大肠埃希氏杆菌因素
Natalia Maldonado,Inmaculada López-Hernández,John Karlsson Valik et al.
Natalia Maldonado et al.
Background: One third of patients with Escherichia coli bacteraemia develop a dysregulated inflammatory response (sepsis/septic shock). Our objective was to investigate whether specific microbiological determinants of E. ...
Longitudinal multiomics analysis of endocrine therapy effects and gut microbiota in breast cancer recurrence [0.03%]
乳腺癌复发的内分泌治疗效果和肠道微生物组纵向多组学分析
Ming-Feng Hou,Chung-Liang Li,Sin-Hua Moi et al.
Ming-Feng Hou et al.
Background: The gut microbiota influences breast cancer development through the estrobolome, a collection of bacterial genes involved in estrogen metabolism. While estrogen and the gut microbiota mutually affect each othe...
The association between childhood body size, adulthood lifestyle, and risk of 50 health conditions [0.03%]
童年时期体格大小、成年期生活方式与50种健康状况风险的关联研究
Xiaomin Zeng,Ruiye Chen,Daiyue Yu et al.
Xiaomin Zeng et al.
Background: The long-term health consequences of childhood body size and whether it can be mitigated by a healthy adult lifestyle remains unclear. This study aims to explore the associations between childhood body size an...