Neutrophil extracellular traps in tumor metastasis: mechanisms, and therapeutic implications [0.03%]
中性粒细胞胞外陷阱在肿瘤转移中的作用:机制及治疗意义
Ni Li,Changmei Yin,Jing Tao
Ni Li
Neutrophil extracellular traps (NETs) are reticular structures composed of DNA fibers, histones, and antimicrobial proteins released by neutrophils. They capture and remove foreign pathogens and play a crucial role in tumor development. The...
Real world feasibility of combining pembrolizumab with radiotherapy in early triple negative breast cancer [0.03%]
派姆单抗与放疗联合治疗三阴性乳腺癌的可行性研究
Riccardo Ray Colciago,Daniele Presti,Carlotta Giandini et al.
Riccardo Ray Colciago et al.
Introduction: Real-world data on the feasibility and potential interaction of concurrent immunotherapy with radiation therapy (RT) remains limited. Herein, we investigated the safety profile of adjuvant pembrolizumab with...
Granular acute lymphocytic leukemia : a case report and literature review [0.03%]
粒细胞性急性淋巴细胞白血病1例及文献复习
Yike Tian,Ping Huang,Mi Jiang et al.
Yike Tian et al.
Acute lymphoblastic leukemia (ALL) is a malignant disease characterized by the clonal proliferation of precursor lymphoblasts in the bone marrow. Granular acute lymphoblastic leukemia (G-ALL) is a rare subtype of ALL, primarily associated w...
Application of artificial intelligence in medical imaging for tumor diagnosis and treatment: a comprehensive approach [0.03%]
人工智能在医学影像肿瘤诊疗中应用的综合方法学研究
Junyan Huang,Yizhen Xiang,Shengqi Gan et al.
Junyan Huang et al.
This narrative review provides a comprehensive and structured overview of recent advances in the application of artificial intelligence (AI) to medical imaging for tumor diagnosis and treatment. By synthesizing evidence from recent literatu...
Neoadjuvant therapy demonstrates both safety and clinical feasibility for renal cell carcinoma patients with tumor thrombus [0.03%]
新辅助治疗对于肾癌伴癌栓患者是安全且可行的
Le Yu,Kewei Chen,Liyuan Ge et al.
Le Yu et al.
Background: While the applications of neoadjuvant therapies on patients diagnosed with renal cell carcinoma (RCC) with tumor thrombus (TT) is growing, the safety of preoperative therapies has yet to be clarified. ...
Whole-exome sequencing in a patient with a history of esophageal squamous cell carcinoma to discriminate recurrent disease from a second primary tumor [0.03%]
食管鳞状细胞癌患者的外显子组测序鉴别复发和原发肿瘤
Guoqing Zhang,Kaiyuan Li,Zheng Ding et al.
Guoqing Zhang et al.
A 52-year-old man who previously underwent McKeown esophagectomy to treat lower thoracic esophageal squamous cell carcinoma (ESCC) and subsequently received radical radiotherapy to treat cervical lymph node malignancy (squamous cell carcino...
PCK1 and ALDH1A1 are identified as biomarkers for inherent drug resistance in hepatocellular carcinoma [0.03%]
PCK1和ALDH1A1被鉴定为肝细胞癌固有耐药生物标志物
Wei Chen,Cheng Zhou,Gao Liu et al.
Wei Chen et al.
Background: Hepatocellular carcinoma (HCC) is a major cause of cancer-related deaths worldwide, often diagnosed at advanced stages with limited treatment options. Despite advancements in systemic therapies, including the ...
Analysis of mortality trends and projected burden of digestive system cancer in China: a nationwide longitudinal analysis (2006-2020) with mortality forecasts to 2045 [0.03%]
中国消化系统癌症死亡趋势分析及至2045年发病负担预测的全国性纵向研究(2006-2020)
Yajing Feng,Junhui Chai,Jichun Zhu et al.
Yajing Feng et al.
Objective: To estimate mortality trends and disease burden of Digestive system cancer (DSC) in China during 2006-2020, using demographic and mortality data from cause-of-death surveillance dataset of China. ...
DNA methylation regulates TREM1 expression to modulate immune responses and drive progression in colorectal neuroendocrine neoplasm as a potential therapeutic target [0.03%]
DNA甲基化通过调节TREM1表达来调控免疫反应并驱动结直肠神经内分泌肿瘤的进展,作为潜在的治疗靶点
Huimin Guo,Guiwen Zheng,Jia Li et al.
Huimin Guo et al.
Background: Colorectal neuroendocrine neoplasms (CrNENs) are rare malignancies with limited therapeutic options and poorly understood molecular mechanisms. The roles of genetic, epigenetic, and immune factors in CrNEN pro...
Global research trends in PARP inhibitors for ovarian cancer: a bibliometric analysis [0.03%]
卵巢癌PARP抑制剂的全球研究趋势计量学分析
Xiaodong Wang,Gouping Ding,Jing He et al.
Xiaodong Wang et al.
This bibliometric analysis maps global research trends on PARP inhibitors (PARPis) in ovarian cancer from January 2021 to May 2025, utilizing 1,434 publications retrieved from the Web of Science Core Collection. Employing Bibliometrix, VOSv...