From gum inflammation to oral cancers: pyroptosis as the molecular torchbearer in periodontitis-driven carcinogenesis [0.03%]
从牙龈炎到口腔癌：焦亡在牙周病驱动的癌症发生中的分子作用机制探究
Shabnam Ghasemzadeh,Farzad Fattah,Sahand Emrahoglu et al.
Shabnam Ghasemzadeh et al.
Periodontitis, a chronic inflammatory disease caused by bacterial infections in dental plaque, results in an environment rich in oxidative stress and pro-inflammatory cytokines, both of which contribute to oral cancers development. One crit...
Ferroptosis and non-coding RNAs in breast cancer: insights into CAF and TAM interactions [0.03%]
乳腺癌中的铁死亡和非编码RNA：CAF和TAM相互作用的新见解
Mohamed J Saadh,Ashok Kumar Bishoyi,Suhas Ballal et al.
Mohamed J Saadh et al.
Ferroptosis, a form of regulated cell death characterized by the accumulation of lipid peroxides, has emerged as a crucial player in cancer biology, particularly in breast cancer. This review article explores the intricate regulation of fer...
LncRNA ADAMTS9-AS1 regulates the proliferation, migration, and invasion of esophageal cancer cells via miR-575/ CADM2 [0.03%]
长链非编码RNA ADAMTS9-AS1通过miR-575/CADM2调节食管癌细胞的增殖、迁移和侵袭
Jinhua Wang,Wei Ji,Hongxia Qu et al.
Jinhua Wang et al.
Background: Esophageal squamous cell carcinoma (ESCC) ranks among the most lethal malignant neoplasms globally, representing a significant risk to public health. ...
A preoperative inflammatory score-based nomogram predicts overall survival after curative hepatectomy for hepatocellular carcinoma [0.03%]
基于术前炎症评分的预测肝癌术后生存获益的列线图模型
Xiaojian He,Xu Peng,Jianliang Duan et al.
Xiaojian He et al.
Objective: This study incorporated preoperative inflammatory scores to develop and validate a nomogram to predict overall survival in patients with hepatocellular carcinoma following curative resection. ...
Potential role of immune-related LncRNAs in prognosis of hepatocellular carcinoma: an integrative study [0.03%]
整合分析免疫相关长链非编码RNA在肝细胞癌预后中的潜在作用
Peidong Miao,Chunxia Pan,Tianyu Li et al.
Peidong Miao et al.
Background: Hepatocellular carcinoma (HCC) represents a significant global health concern with persistently high incidence and mortality rates. Immune-related long non-coding RNAs (lncRNAs) may play crucial roles in the p...
Systematic analysis identifies CDKN2A as a prognostic biomarker for hepatocellular carcinoma [0.03%]
系统分析鉴定出CDKN2A是肝细胞癌的预后生物标志物
Shilin He,Yanling Zhang,Junjie Xu et al.
Shilin He et al.
Background: Hepatocellular carcinoma (HCC) ranks as the fifth most prevalent malignancy worldwide. Disruptions in copper homeostasis adversely affect liver function. Cuproptosis, a recently defined form of regulated cell ...
SNX7 mediates inhibition of autophagy in prostate cancer via activation of CFLIP expression [0.03%]
SNX7通过激活CFLIP表达介导前列腺癌自噬抑制作用
Liang Qin,Fan Yang,Zhuifeng Guo et al.
Liang Qin et al.
Background: Prostate cancer (PC) is a major health concern among men worldwide, yet its underlying molecular mechanisms remain incompletely understood. Identifying key regulatory genes and signaling pathways involved in P...
CD44 overexpression as a mediator of drug resistance in oral cancer: a meta-analysis unveiling molecular underpinnings and therapeutic implications [0.03%]
CD44过表达作为口腔癌耐药介导者的作用：分子作用机制及治疗意义的meta分析研究
Shushu Miao,Caiqiong Wang,Anqi Zheng
Shushu Miao
Background: Therapeutic resistance in oral cancer, with cancer stem cells (CSCs) playing a pivotal role, remains a major clinical challenge. CD44, a key CSC marker, has been implicated in multidrug resistance mechanisms t...
KLB as a potential prognostic biomarker and therapeutic target in colorectal cancer: insights from multi omics and single cell analyses [0.03%]
作为结直肠癌预后生物标志物和治疗靶点的KLB：多组学及单细胞分析的新见解
Xiaofei Bi,Wenjin Zhang,Meimei Shen et al.
Xiaofei Bi et al.
Background: Colorectal cancer (CRC) is one of the most common gastrointestinal malignancies, with a rising global incidence. Despite advances in diagnosis and treatment, effective biomarkers for early detection and target...