Long non-coding RNA-based single and combination independent prognostic biomarkers for hepatocellular carcinoma [0.03%]
基于长链非编码RNA的肝细胞癌独立预后单生物标志物和联合生物标志物
Long-Bin Jeng,Horng-Ren Yang,Chiao-Fang Teng
Long-Bin Jeng
Although significant advances have been made in the prevention and therapy, hepatocellular carcinoma (HCC) is still one of the most frequent and fatal human cancers worldwide. Discovery of independent prognostic biomarkers for the early ide...
Mendelian randomization analysis reveals causal roles of inflammatory cytokines in thyroid cancer pathogenesis [0.03%]
孟德尔随机化分析揭示了炎症细胞因子在甲状腺癌发病机制中的因果作用
Bo Liu,Tingting Zhang,Jihua Han et al.
Bo Liu et al.
Thyroid cancer is a common endocrine malignancy associated with various inflammatory factors. This research aimed to explore the causal relationships between 41 inflammatory factors and the risk of thyroid cancer using Mendelian randomisati...
Preliminary study on SIRI dynamic changes for the efficacy prediction and prognosis evaluation of advanced cancer patients treated with immunotherapy [0.03%]
基于免疫治疗的晚期癌症患者疗效预测及预后评估的SIRI动态变化初步研究
Xiuzhen Wei,Yinghai Liu,Huijuan Wang et al.
Xiuzhen Wei et al.
Diagnostic and management strategies for retroperitoneal leiomyosarcoma invading the inferior vena cava: a case report [0.03%]
侵袭下腔静脉的腹膜后平滑肌肉瘤的诊断和处理策略：病例报告
Haoxiang Zhu,Huipeng Zhu
Haoxiang Zhu
Background: Retroperitoneal leiomyosarcoma represents a poor-prognosis malignancy for which current clinical treatment options remain limited. This study may further help bridge the gap in available therapeutic modalities...
Integrated pan-cancer and melanoma-specific analysis of angiopoietin-2: prognostic value, immune microenvironment modulation, and ceRNA network regulation [0.03%]
血管生成素-2的泛癌和黑色素瘤特异性分析：预后价值，免疫微环境调节和ceRNA网络调控
Xuejun Ni,Xiaofen Wan,Beichen Cai et al.
Xuejun Ni et al.
Objective: This research seeks to comprehensively explore the expression patterns of Angiopoietin-2 (ANGPT2) in pan-cancer and examine its relationship with clinical outcomes, tumor immune microenvironment dynamics, and b...
Upregulation of EMP3 in acute myeloid leukemia: a study based on data mining, RT-qPCR and immunohistochemistry [0.03%]
急性髓系白血病中EMP3的上调表达：基于数据挖掘、RT-qPCR和免疫组化研究
Angui Liu,Cong Yu,Xianwei Peng et al.
Angui Liu et al.
Background: Epithelial Membrane Protein 3 (EMP3) has been associated with multiple malignancies, but its expression patterns and clinical significance in acute myeloid leukemia (AML) remain poorly characterized. ...
N(6)-methyladenosine modification of ADGRA3 by ZC3H13 suppresses papillary thyroid cancer cell malignancy by inactivating the PI3K/Akt/mTOR signaling pathway [0.03%]
ZC3H13介导的ADGRA3 N6-甲基腺苷修饰通过抑制PI3K / Akt / mTOR信号通路抑制乳头状甲状腺癌细胞恶性行为
Li Cai,Linghui Zhang,Zhaodan Yan
Li Cai
Background: N(6)-methyladenosine (m6A) modification is a posttranscriptional regulatory mechanism involved in tumorigenesis. Adhesion G protein-coupled receptor A3 (ADGRA3) has been implicated in various biological proces...
TMT-based proteomics analysis identifies RPLP1 as a key protein target in ursolic acid Inhibition of colorectal cancer [0.03%]
基于TMT标记的定量蛋白质组学研究发现金丝桃素通过靶向RPLP1抑制结直肠癌
Li-Min Zhu,Hai-Xia Shi,Zhen-Ye Xu et al.
Li-Min Zhu et al.
Purpose: Ursolic Acid (UA), a triterpenoid extracted from Hedyotis Diffusa Willd. (HDW), is known for its anti-inflammatory, antioxidant, and antitumor effects. Nevertheless, the mechanisms underlying UA's anti-colorectal...
Predictive value of MHC-related genes in cervical cancer: implications for immunotherapy and prognostic nomogram development [0.03%]
人白细胞抗原相关基因在宫颈癌免疫治疗中的预测价值及预后模型的建立
Meili Xi,Xiaoqing Wang,Xiao Xu et al.
Meili Xi et al.
Background: While cervical cancer (CC) is increasingly detected at earlier stages due to improved screening, clinical dilemmas persist in stratifying precancerous lesions and managing advanced disease. Major histocompatib...
Clinical significance of ANXA9 expression in colorectal cancer and its impact on immune evasion and drug resistance [0.03%]
ANXA9在结直肠癌表达的意义及其对免疫逃逸和耐药性的影响
Mingyang Hong,Qian Dong,Huiming Zhu et al.
Mingyang Hong et al.
Background: Colorectal cancer (CRC) is a major global health challenge, creating an urgent need to find new biomarkers that improve early detection and treatment success. While studies suggest that ANXA9 contributes to ca...