SSBP1 is a prognostic biomarker and promotes the progression of lung adenocarcinoma via p53 signaling pathway [0.03%]
SSBP1是一种预后生物标志物并通过p53信号通路促进肺腺癌进展
Dengrong Hao,Hao Wang
Dengrong Hao
SSBP1, a mitochondrial single-strand binding protein, was found to be significantly overexpressed in lung adenocarcinoma (LUAD) tissues, indicating its potential as a diagnostic biomarker. However, its function in LUAD remained largely uncl...
Causal effects of circulating inflammatory proteins on colorectal cancer: a Mendelian randomization and Spatial transcriptomic study [0.03%]
循环炎症蛋白与结直肠癌因果关系的孟德尔随机化及空间转录组学研究
Mei Bai,Bo Wu,Jie Li et al.
Mei Bai et al.
Objective: This study aimed to investigate the potential causal relationships between 91 circulating inflammatory proteins and colorectal cancer (CRC) using a two-sample bidirectional Mendelian randomization (MR) framewor...
The reduced DLG5 promotes doxorubicin resistance in breast cancer cells MCF-7 through regulating autophagy [0.03%]
下调的DLG5通过调节自噬促进乳腺癌细胞MCF-7对多柔比星的耐药性
Jingmin Che,Xusheng Wang,Bo Chen et al.
Jingmin Che et al.
Breast cancer is among the most prevalent malignant tumors in women globally, with adriamycin (ADM) demonstrating considerable efficacy as a first-line chemotherapeutic agent. The problem of adriamycin resistance significantly impairs its e...
Implementation of whole genome sequencing in cancer management: modelling and sensitivity analysis using system dynamics [0.03%]
基于系统动力学的癌症管理中全基因组测序实施及敏感性分析模型研究
Hadi Akbarzadeh Khorshidi,Marzieh Soltanolkottabi,Maarten J IJzerman
Hadi Akbarzadeh Khorshidi
Precision oncology using biomarkers and genomic testing facilitates individualised diagnosis and consequently treatment for cancer patients. Standard of Care is conducted through assays of biomarkers for treatment selection. However, Whole ...
Risk factors and prognostic nomogram for distant metastasis in patients with PTMC [0.03%]
PTMC患者远处转移的风险因素及预后评估列线图模型
Qiaoqiao Liang,Leitao Yu
Qiaoqiao Liang
There is controversy regarding treatment selection for papillary thyroid microcarcinoma (PTMC), and a prediction model for PTMC distant metastasis (DM) is critically needed to guide treatment planning. Therefore, we study retrospectively an...
Pilot research on predicting the sub-volume with high risk of tumor recurrence inside peritumoral edema using the ratio-maxiADC/meanADC from the advanced MRI [0.03%]
基于高级磁共振的比值最大ADC/平均ADC预测肿瘤周围水肿区高危亚区复发的风险研究
Jinling Zhang,Haobin Liu,Yuxiao Wu et al.
Jinling Zhang et al.
Purpose: This study aimed to identify key image parameters from the traditional and advanced MR sequences within the peritumoral edema in glioblastoma, which could predict the sub-volume with high risk of tumor recurrence...
From texture analysis to artificial intelligence: global research landscape and evolutionary trajectory of radiomics in hepatocellular carcinoma [0.03%]
从纹理分析到人工智能：肝细胞癌放射组学全球研究格局与演变路径分析
Xiong Teng,Quan-Neng Luo,Yi-Di Chen et al.
Xiong Teng et al.
Background: Hepatocellular carcinoma (HCC) poses a substantial global health burden with high morbidity and mortality rates. Radiomics, which extracts quantitative features from medical images to develop predictive models...
Research of SLC7A11 to estimate the prognosis and immune infiltration landscape for breast cancer [0.03%]
SLC7A11在乳腺癌预后及免疫浸润中的研究
Xiangjie Xue,Yicheng Zhi,Lu Wang et al.
Xiangjie Xue et al.
SLC7A11, a key factor protecting cancer cells from oxidative stress, is upregulated and shows prognostic significance in amounts of malignant tumors largely while its role still remains indistinct in breast cancer. We conduct an explicit an...
Selection of tumor invasion-related genes to build a prognostic model and predict immune response and potential drugs for esophageal cancer patients based on WGCNA [0.03%]
基于WGCNA的食管癌患者肿瘤浸润相关基因的选择、预后模型构建及其免疫反应和潜在药物预测研究
Xueqiong Deng,Yiming Liu
Xueqiong Deng
Background: Esophageal cancer (EC) has a high incidence and is highly invasive. It is meaningful to employ invasion-related genes (IRGs) to predict patients' prognosis. ...
Novel radiation-derived gene blueprint stratifying patients with breast cancer [0.03%]
新颖的电离辐射衍生基因谱型可对乳腺癌患者进行分层
Hao Zhang,HongHua Lin,Enyi Qiu et al.
Hao Zhang et al.
Background: Breast cancer (BC) is a prevalent global malignancy with a high recurrence rate. The effectiveness of predictive, preventive, and personalized treatment strategies is limited by a lack of reliable prognostic b...