Yu-Juan Shi,Yu-Sheng Yang,Da-Bing Ren et al.
Yu-Juan Shi et al.
Background: Oesophageal cancer is the seventh leading cause of cancer mortality worldwide. Prostate cancer metastasis to the oesophagus is exceedingly rare. We report an 82-year-old male patient. He presented to the gastr...
Integrated multi-omics analysis reveals PTM networks as key regulators of colorectal cancer progression and immune evasion [0.03%]
整合多组学分析揭示了PTM网络是结直肠癌进展和免疫逃逸的关键调节因子
Guiting Yang,Liu Ji,Chengmei Lv et al.
Guiting Yang et al.
Background: Colorectal cancer (CRC) is a leading cause of cancer mortality, with treatment resistance often driven by molecular heterogeneity and an immunosuppressive tumor microenvironment (TME). Post-translational modif...
Multi-omics analysis reveals the prognostic value and immunomodulatory role of CTSW in breast cancer [0.03%]
多组学分析揭示CTSWS在乳腺癌中的预后价值和免疫调节作用
Xvliang Liu,Zeli Yin,Pengju Xi et al.
Xvliang Liu et al.
Background: The inherent complexity and biological heterogeneity of breast cancer pose substantial challenges to the development of effective personalized therapies. The exploration of novel biomarkers, particularly those...
Renal cell carcinoma unclassified with medullary phenotype: a case report and review of the literature [0.03%]
肾癌未分类伴有髓质表型：1例报道及文献复习
Mengyao Li,LuLu Zhang,Yulei Li et al.
Mengyao Li et al.
Renal medullary carcinoma (RMC) is a highly aggressive tumor characterized by SMARCB1/INI1 deficiency, predominantly affecting young blacks with sickle cell disease. Recently, the provisional diagnostic entity "renal cell carcinoma unclassi...
Disulfidptosis OXSM serves as a potential prognostic biomarker and correlates with immune infiltrates in glioma [0.03%]
二硫化物Otosis OXSM可作为胶质瘤预后生物标志物并介导免疫浸润
Jinchao Zhu,Yao Ke,Yijuan Fan et al.
Jinchao Zhu et al.
Background: Glioma, a common primary brain tumor arising from glial cells, presents significant therapeutic challenges due to its diverse and complex biological behavior. While disulfidptosis has recently emerged as a nov...
The effect of thyroid nodule location in ultrasound on the diagnosis of papillary thyroid carcinoma [0.03%]
超声检查甲状腺结节位置对乳头状癌的诊断价值
Jia-Fei Hu,Jun Xu,Li-Ping Gao et al.
Jia-Fei Hu et al.
Objective: Exploring the role of nodule location in the diagnosis of papillary thyroid carcinoma in Chinese patients. Methods: This stu...
Bibliometric analysis of immune dysregulation and immunotherapy in mismatch repair-deficient colon cancer [0.03%]
错配修复缺陷型结直肠癌免疫失调节和免疫治疗的文献计量分析
Xingtao Jin,Hao Wang,Ye Han et al.
Xingtao Jin et al.
Background: Mismatch repair deficiency (dMMR) is observed in 12-15% of sporadic colon carcinomas. dMMR tumors have unique genetic characteristics, with mutation rates 10 to 100 times higher than those of tumors with intac...
Early antibiotic exposure does not affect prognosis in patients with advanced gastric cancer treated with PD-1 inhibitors [0.03%]
新辅助抗肿瘤治疗对胃癌患者PD-1抑制剂疗效无影响
Ziting Qu,Yuyan Wang,Zhikun Wang et al.
Ziting Qu et al.
Purpose: To explore the prognostic impact of antibiotic exposure during programmed death receptor-1 (PD-1) inhibitor therapy in patients with advanced gastric cancer (AGC). ...
Amyloid precursor protein accumulation in glioblastoma is associated with altered synaptic dynamics and immune suppression [0.03%]
淀粉样前体蛋白在胶质母细胞瘤中的积累与突触动力学改变和免疫抑制有关
Tyrel R Porter,Mikhail Inyushin,Lilia Kucheryavykh
Tyrel R Porter
Increased amyloid precursor protein (APP), including both mRNA and protein expression, has been linked to glioblastoma (GBM) yet the physiological effects are poorly understood. In this study, we investigated the relationship between APP pr...
Gut microbiota as a hidden modulator of chemotherapy: implications for colorectal cancer treatment [0.03%]
肠道菌群作为化疗的隐秘调节者：对结直肠癌治疗的意义
Zahra Sadeghloo,Amir Sadeghi
Zahra Sadeghloo
Colorectal cancer (CRC) is a major cause of cancer morbidity and mortality worldwide, with chemotherapy remaining a cornerstone of treatment. Emerging evidence reveals that the gut microbiota significantly influences the metabolism, efficac...