Poly(ADP-ribose) polymerase-1 in breast cancers: expression level and its association in various molecular subtypes with a focus in Africa [0.03%]
乳腺癌中聚腺苷二磷酸核糖转移酶-1的表达水平及其与不同类型分子亚型的关系（重点关注非洲）
James J Yahaya,Advera I Ngaiza
James J Yahaya
Poly(ADP-ribose) polymerases (PARPs) are important nuclear protein enzymes (NPEs) that play crucial functions in different cellular activities including DNA repair, gene transcription, post-translational, and cell death. Of the 17 establish...
Clinicopathological features and prognostic factors of apocrine carcinoma of the breast in a cohort of 63 patients [0.03%]
63例乳腺大汗腺癌的临床病理特征及预后因素分析
Ryusei Yoshino,Nozomi Hatanaka,Kengo Takahashi et al.
Ryusei Yoshino et al.
The multifaceted role of RNF213 in oncogenesis: current insights and future research directions [0.03%]
RNF213在肿瘤发生中的作用及未来研究方向
Guicheng Kuang,Hang Ji,Hailan Yang et al.
Guicheng Kuang et al.
Moyamoya disease (MMD)-associated gene RNF213 has emerged as a critical player in the pathogenesis of a spectrum of cancers beyond its established role in MMD. This review synthesizes current understanding of RNF213's structural characteris...
ATG7-induced autophagy inhibits ferroptosis and promotes the progression of colorectal adenocarcinoma [0.03%]
ATG7诱导的自噬通过抑制铁死亡促进结肠腺癌进展
Minyuan Chen,Ziqi Meng,Limei Zhu et al.
Minyuan Chen et al.
Purpose: To investigate the role of ATG7-induced autophagy in regulating ferroptosis and promoting the progression of colorectal adenocarcinoma (COAD). Me...
Rui Shi,Shao-Ming Li,Ling Gao et al.
Rui Shi et al.
Background: Parotid gland tumor is the most common salivary gland tumors. Benign tumors account for about 80% of parotid gland tumors. However, due to the special anatomical location of the parotid gland and the different...
Case report: metachronous male metastatic breast and colon cancer in a BRCA2 mutation carrier [0.03%]
病例报告：BRCA2基因突变携带者继发男性乳腺癌和结肠癌转移案
Emiliana Larionesi,Oana-Nicoleta Pilet,Christos Sotiriou
Emiliana Larionesi
Introduction and importance: Male breast cancer (MBC) is rare and typically diagnosed at later stages, often in older men. Pathogenic BRCA2 mutations are implicated in a significant proportion of MBC cases and may confer ...
Low pre-treatment neutrophil-to-lymphocyte ratio predicted a better survival in recurrent/metastatic cervical cancer treated with PD-1/PD-L1 inhibitors [0.03%]
术前外周血中性粒细胞与淋巴细胞比值降低预示宫颈复发/转移癌使用PD-1/PD-L1抑制剂治疗有更好生存获益
Jing Li,Yulu Wang,Jiayu Pei et al.
Jing Li et al.
Background: A precise predictor is urgently needed for immunotherapy in cervical cancer (CC), which would be very helpful for disease monitoring. Thus, we explore the relationship between pre-treatment neutrophil-to-lymph...
Multidimensional transcriptomic and immune profiling of papillary thyroid cancer: bridging molecular networks, disease stage, survival outcomes, and drug discovery [0.03%]
多维转录组和免疫表型描绘乳头状甲状腺癌：分子网络、疾病阶段、生存结果及药物发现之间的桥梁研究
Haitham Al-Madhagi
Haitham Al-Madhagi
Thyroid cancer ranks tenth among the deadliest cancers globally. Papillary thyroid cancer (PTC) represents the majority (> 80%) of all thyroid cancer types. Albeit radioactive iodine therapy achieves a great deal of success rate and efficac...
Tumor size in the management of preoperative radiotherapy for locally advanced rectal cancer [0.03%]
肿瘤大小在局部晚期直肠癌术前放疗中的作用
Xiaohong Zhong,Huaqin Lin,Qizhen Huang et al.
Xiaohong Zhong et al.
Background: To identify tumor size could be taken as a decision-making factor in the management of preoperative radiotherapy (RT) for patients with locally advanced rectal cancer (LARC). ...
Pharmacological inhibition of NMDA receptors reduces migration and viability in triple-negative inflammatory breast cancer cell lines [0.03%]
NMDA受体的药理学抑制可减少三阴性炎性乳腺癌细胞系的迁移和活力
Laura L Mendez-Santacruz,Xavier S Bittman-Soto,Alexie Molina-Nieves et al.
Laura L Mendez-Santacruz et al.
Purpose: NMDA receptors (NMDARs), best known for their role in neuronal signaling, have been linked to breast cancer progression and metastasis, but their involvement in Inflammatory Breast Cancer (IBC) remains unexplored...