Machine learning applications in the detection and treatment of esophageal cancer [0.03%]
机器学习在食管癌诊断和治疗中的应用
Fangyuan Long,Hongru Zhang,Shungeng Zhang et al.
Fangyuan Long et al.
Esophageal cancer (EC) is a gastrointestinal malignancy associated with a poor prognosis worldwide. It is characterized by an insidious onset, marked tumor heterogeneity, and complex diagnostic and therapeutic pathways. Consequently, clinic...
miR-34a-5p-mediated inhibition on the KRT5/DSP axis blunts cancer stem cell properties and cisplatin resistance in non-small cell lung cancer [0.03%]
microRNA-miR-34a-5p介导的KRT5/DSP轴抑制可削弱非小细胞肺癌中的癌症干细胞特性及顺铂耐药性
Yelin Song,Zuowei Li
Yelin Song
The survival rate of patients diagnosed with non-small cell lung cancer (NSCLC) are significantly influenced by drug resistance and metastasis with cancer stem cells (CSCs). MicroRNAs (miRNAs) impact on the progression of various human dise...
Combination of p-STAT5, CRLF2 and copy number alterations as a potential indicator of a high-risk subgroup of acute lymphoblastic leukemia [0.03%]
p-STAT5、CRLF2及拷贝数变异的联合作为高危急性淋巴细胞白血病亚群潜在标记的研究
Eman O Rasekh,Maha Saleh,Marwa Hanafy et al.
Eman O Rasekh et al.
Purpose: Signal transduction and transcription activation5 (STAT5) drives leukemic cell survival and treatment resistance in acute lymphoblastic leukemia (ALL), linking its activation to poor prognosis and highlighting it...
A novel mitochondrial-related gene signature for assessing the tumor immune microenvironment and predicting prognosis in human glioma [0.03%]
一种新的线粒体相关基因特征用于评估肿瘤免疫微环境及人类胶质瘤预后预测
Zakia Harmak,Oumayma Naji,Hamza Baddi et al.
Zakia Harmak et al.
Background: Gliomas represent the most prevalent and aggressive primary brain tumors in adults. Accumulating data suggest a strong connection between mitochondrial dysfunction and cancer development. However, signature ma...
Sarcomatoid adrenocortical carcinoma with aggressive disease course: a rare case report and literature review [0.03%]
侵袭性病程的肉瘤样肾上腺皮质癌一例及文献复习
Xin-Xin Xu,Guang-Fu Zhou,Cheng-Zhou Du et al.
Xin-Xin Xu et al.
Introduction: Sarcomatoid Adrenocortical Carcinoma (SAC) is an extremely rare, highly aggressive, and poorly differentiated subtype of Adrenocortical Carcinoma (ACC). To date, only 38 cases have been reported worldwide. N...
Machine learning-based integration develops a novel lysosome-related prognostic signature associated with prognosis and immune infiltration landscape in acute myeloid leukemia [0.03%]
基于机器学习的整合开发了一种新型溶酶体相关预后标志物，用于急性髓系白血病的预后和免疫浸润景观分析
Linna Lu,Xueliang Jiang,Jun Lu et al.
Linna Lu et al.
Background: Lysosomes are essential for intracellular degradation and recycling, and changes in their function significantly contribute to tumor growth. Nonetheless, the exact role of lysosome-related genes (LRGs) in the ...
A stemness-associated prognostic model identifies CXCR4 as a key regulator of M2 macrophage polarization via lactate in stomach adenocarcinoma [0.03%]
与干细胞相关的预后模型确定CXCR4通过乳酸调节胃腺癌中M2巨噬细胞极化的关键调节因子
Ting Gao,Yang Hong,Jie Yang et al.
Ting Gao et al.
Purpose: Cancer stem cells (CSCs) serve as critical drivers of cancer relapse, metastasis and drug resistance, and are closely associated with poor prognosis. Increasing evidence has highlighted the regulatory effects of ...
Transcriptomic identification of key genes influencing m7G modification in thyroid carcinoma and experimental validation [0.03%]
甲状腺癌中m7G修饰关键影响基因的转录组学鉴定及实验验证
Bo Li,Liying Zhu,Jiewu Zhang
Bo Li
Background: N7-methylguanosine (m7G) modification plays a critical role in RNA metabolism and is increasingly recognized for its implications in cancer biology. It can influence RNA stability, translation efficiency, and ...
A bibliometric analysis of artificial intelligence in ovarian cancer research from 2006 to 2025 [0.03%]
2006至2025年卵巢癌人工智能研究的文献计量分析
Jiujie He,Wanting Zhou,Yujun He et al.
Jiujie He et al.
Background: Ovarian cancer is a gynecological malignancy associated with high mortality and poses significant clinical challenges in early diagnosis and precision treatment. Although the rapid advancement of artificial in...
Shilin You,Min Wang,Tengyue Zhang et al.
Shilin You et al.
Purpose: This review aims to address the therapeutic potential of new generation of oncolytic viruses (OVs) for liver cancer with the focus on hepatocellular carcinoma (HCC). ...