Association of FANCD2, TFPI, and CD33 genes with prognosis of lung adenocarcinoma: a bioinformatics study [0.03%]
FANCD2、TFPI和CD33基因与肺腺癌预后关联的生物信息学研究
Guixin He,Ting Ge,Lijiang Ji et al.
Guixin He et al.
Background: Lung adenocarcinoma (LUAD) is characterized by high mortality and a complex pathogenesis. Despite significant advancements in targeted therapies and immunotherapies, patient prognosis remains poor, and there i...
WNK1 promotes head and neck squamous cell carcinoma progression through activation of NF-κB signaling pathway [0.03%]
WNK1通过激活NF-κB信号通路促进头颈鳞状细胞癌进展
Ru-Zhen Chen,Rui Li,Bing-Lin Cheng et al.
Ru-Zhen Chen et al.
Yuqing Xu,Hucheng Zhang,Haipeng Yu
Yuqing Xu
Background: Hepatocellular carcinoma (HCC) is a highly prevalent primary liver cancer, accounting for over 90% of all liver cancer cases worldwide and ranking as the third leading cause of cancer-related deaths. The emerg...
Multimodal imaging and advanced quantitative techniques for HER-2 status prediction in breast cancer [0.03%]
乳腺癌HER-2状态预测的多模态影像与高级定量技术
Qingxue Wang,Ning Zheng,Qingqing Yu et al.
Qingxue Wang et al.
HER-2-positive breast cancer is a biologically distinct subtype, accurate early assessment of HER-2 status is therefore critical for guiding personalized treatment. Currently mainly detected through immunohistochemistry (IHC) and fluorescen...
Endoscopic submucosal dissection in Helicobacter pylori-negative early gastric adenocarcinoma with diffuse large B-cell lymphoma: a two-case report and literature review [0.03%]
幽门螺杆菌阴性早期胃腺癌合并弥漫大B细胞淋巴瘤的内镜下黏膜下剥离术：2例报告及文献复习
Bo Zhang,Xue-Guo Sun,Qing-Juan He et al.
Bo Zhang et al.
We describe two rare cases of synchronous early gastric adenocarcinoma (EGA) and diffuse large B-cell lymphoma (DLBCL) involving the stomach and colon in Helicobacter pylori-negative patients. Case 1: A 61-year-old male presenting with abdo...
Clinical study of aumolertinib versus osimertinib in the treatment of EGFR-mutated advanced non-small cell lung cancer [0.03%]
奥美替尼对比奥希替尼治疗EGFR突变型晚期非小细胞肺癌的临床研究
Sheng-Xi Yang,Jia-De Zhu,Ling Ma et al.
Sheng-Xi Yang et al.
Background: To compare the efficacy and safety of aumolertinib and osimertinib in the treatment of advanced non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations. ...
Malignant progression of MES-like cells mediated by COL22A1 in the spatial heterogeneity of glioblastoma [0.03%]
胶质母细胞瘤空间异质性中COL22A1介导MES样细胞恶性进展
Guangyuan Chen,Zhonghua Fu,Xulin He et al.
Guangyuan Chen et al.
Glioblastoma (GBM), a highly aggressive malignant brain tumor, leads to poor clinical outcomes and low long-term survival rates. Using bioinformatics approaches, we analyzed single-cell RNA sequencing (scRNA-seq) data (GSE273274) from gliom...
Yingzhi Zhou,Tian Peng,Jiahan Zhang et al.
Yingzhi Zhou et al.
Pyroptosis is a novel form of programmed cell death that depends on gasdermin-mediated pore formation in the plasma membrane and the release of inflammatory factors. Pyroptosis is closely linked to the occurrence and progression of almost a...
Jinming Tang,Min Su,Yuhang Xiao et al.
Jinming Tang et al.
An essential category of non-protein-coding RNA molecules, known as long noncoding RNAs (lncRNAs), are naturally occurring RNA sequences exceeding 200 nucleotides in length. Accumulating evidence has unveiled the significant involvement of ...
Binbin Hu,Tianyu Ma,Dongli Zhou et al.
Binbin Hu et al.
RNA plays a variety of critical roles in cellular environments, including serving as a structural molecule, messenger molecule, translational carrier, and effector molecule. During the execution of these functions, RNA undergoes diverse pos...