A clinical analysis of 19 cases of chordomas with poor differentiation treated using diverse therapeutic modalities [0.03%]
不同治疗方式的19例低分化软骨肉瘤临床分析
Wei Wang,Yajie Cui,Renkun Nie et al.
Wei Wang et al.
Background: There is an urgent need to enhance clinicians' ability to diagnose and treat chordomas with poor differentiation, particularly poorly differentiated chordomas (PDCs), through clinical case analysis. ...
Global trends in retroperitoneal sarcomas surgery: a bibliometric analysis from 2005 to 2024 [0.03%]
2005-2024年腹膜后肉瘤手术的全球趋势：文献计量分析
Junxiang Zhang,Kai Deng,Yukai Zheng et al.
Junxiang Zhang et al.
Objective: Retroperitoneal sarcomas are located in the retroperitoneum, characterized by a low incidence rate but a high degree of aggressiveness. Currently, surgery stands as the only curative treatment. This literature ...
The global, regional, and national burden of acute lymphoblastic leukemia, 1990 to 2021: a cross-sectional analysis from the 2021 global burden of disease study [0.03%]
1990年至2021年全球、区域和国家急性淋巴细胞白血病疾病负担：来自2021年全球疾病负担研究的横断面分析
Chen Yuan,Meiping Zhu,Yi Shi et al.
Chen Yuan et al.
Background: Acute lymphoblastic leukemia (ALL) remains a major public health challenge, yet its global burden and epidemiological trends are inadequately characterized. This study evaluates the global burden of ALL from 1...
Development of a novel 4-protein signature for prognostic prediction in hepatitis B virus-induced hepatocellular carcinoma [0.03%]
用于乙型肝炎病毒诱导的肝细胞癌预后预测的新型4蛋白标志物的研发
HaiFeng Xie,Yuhong Zhao,Xianzhong Luo et al.
HaiFeng Xie et al.
Background: Hepatocellular carcinoma (HCC) remains a major global health challenge, with the pathogenesis of HBV-induced HCC incompletely understood. Due to HCC's significant heterogeneity, more accurate prognostic models...
CD8 T cell exhaustion-associated LncRNA signature reveals novel molecular subtypes and immune targets in hepatocellular carcinoma [0.03%]
基于肝细胞癌中耗竭的CD8T细胞相关长链非编码RNA特征鉴定新的分子亚型及免疫治疗靶点
Jiahui Feng,Dezhong Yan,Lingling Jiang et al.
Jiahui Feng et al.
Background: Hepatocellular carcinoma (HCC) presents challenges and opportunities for immunotherapy due to its intricate immune microenvironment. Exhausted CD8 T cells (CD8Tex) are pivotal in this context but are inadequat...
Bibliometric analysis of global research trends in delivery systems for breast cancer immunotherapy [0.03%]
全球乳腺癌免疫治疗递送系统研究趋势的 bibliometrics 分析
Jun-Yi Yang,Xin-Yu Li,Si-Lu Xiang et al.
Jun-Yi Yang et al.
Background: Breast cancer (BC) immunotherapy exhibits disappointingly low response rates and faces significant challenges including systemic toxicity and poor tumor penetration, while delivery systems (DSs) offer revoluti...
Advances in biomarkers of resistance to KRAS mutation-targeted inhibitors [0.03%]
针对KRAS突变靶向抑制剂的耐药生物标志物研究进展
Lihao Wang,Dandan Wei,Shanshan Li et al.
Lihao Wang et al.
KRAS mutations represent the most common driver genetic alterations in multiple malignant tumors, particularly exerting well-defined oncogenic driver roles in non-small cell lung cancer, colorectal cancer, and pancreatic ductal adenocarcino...
Sulforaphane from broccoli, an epigenetic modulator in cancer cells [0.03%]
源于西兰花的诱导癌细胞表观遗传修饰的活性物质硫氰化合物的研究进展
Soayébo Dabre,Abdou Azaque Zoure,Lassina Barro et al.
Soayébo Dabre et al.
The consumption of cruciferous vegetables offers several health benefits due to some of their compounds. Sulforaphane (SFN), a compound found in cabbage and broccoli, has received special attention in recent years due to its anticancer acti...
Untargeted metabolomics reveals gut microbiota metabolite alterations and their correlation with serum biomarkers in gastric cancer patients from high-altitude regions [0.03%]
未靶向代谢组学揭示胃癌患者肠道微生物代谢产物变化及其与血清生物标志物的相关性
Linghong Zhu,Zhaoxin Jin,Yanqing Ma et al.
Linghong Zhu et al.
Objective: This study aimed to characterize gut microbiota-derived faecal metabolites and evaluate their associations with serum biochemical indices and tumor markers in gastric cancer patients residing in high-altitude r...
Alpha 5 integrin as a prognostic biomarker for survival in carcinomas: a systematic review [0.03%]
α5整合素作为癌转移和患者生存预后生物标志物的系统评价研究进展
Natalie Ap Rodrigues Fernandes,Milena Moraes de Carvalho,Lélio Fernando Ferreira Soares et al.
Natalie Ap Rodrigues Fernandes et al.
Altered integrin expression in carcinomas has been associated with tumor aggressiveness, including survival outcomes. The alpha 5 (α5) integrin is associated with increased proliferation, invasion, migration, and metastasis in various type...