Fedratinib inhibits ovarian cancer progression by downregulating QPCT expression [0.03%]
Fedratinib通过下调QPCT表达抑制卵巢癌进展
Ying Dong,Yue Deng,Longyan Zhu et al.
Ying Dong et al.
Objective: Among gynecological malignant tumors, ovarian cancer is one of the most common, and the death rate is the highest. However, most ovarian cancer patients will be resistant to the application of Olaparib. Searchi...
The influence of ferroptosis-associated gene HSPA5 on the prognosis and immune evasion of lung adenocarcinoma [0.03%]
铁死亡相关基因HSPA5对肺腺癌预后及免疫逃逸的影响
Lei Xiong,Xiang Gao,Lixin Wang et al.
Lei Xiong et al.
Objective: Utilizing bioinformatics technology, we aim to screen for differentially expressed genes associated with ferroptosis in lung adenocarcinoma, aiming to identify ferroptosis-related genes that significantly impac...
Advances and challenges in immunotherapy and molecular imaging for hepatocellular carcinoma [0.03%]
免疫治疗和分子影像在肝细胞癌中的进展与挑战
Tu Haibin
Tu Haibin
Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality, with advanced disease resistant to conventional therapies. Targeted combined immunotherapy, such as ICIs with TKIs or anti-VEGF agents, has improved outcomes, but hetero...
Causal association between mitochondrial genes and colorectal cancer: a multi-omics Mendelian randomization study [0.03%]
线粒体基因和结直肠癌的因果关联：一项多组学孟德尔随机化研究
Zhandong Zhang,Shuaibing Lu,Liangqun Peng et al.
Zhandong Zhang et al.
Objective: Colorectal cancer (CRC) is the leading cause of cancer-related morbidity and mortality globally. Despite the established link between mitochondrial dysfunction and various cancers, including CRC, the precise ro...
Elucidating the causal triad of cardiovascular disease, cancer, and lipid traits: a bidirectional Mendelian randomization study with genetic mediation analysis [0.03%]
一种遗传中介分析的双向孟德尔随机化研究阐明心血管疾病、癌症和脂质特征之间的因果关系三元组
Weijie Wu,Aiming Zeng,Yunzhe Yu et al.
Weijie Wu et al.
Background: Previous studies have indicated the association between cardiovascular disease (CVD), cancer and lipid, while the causality remain unclear. We aim to elucidate the causality among them and potential mediating ...
Yi Guo,Gang Zheng,Yu Fan et al.
Yi Guo et al.
Cancer immunotherapy is now defined as enhancing the immune function of patients through active or passive methods, such as biological therapy, to achieve the goal of killing tumor cells. With increasing morbidity and mortality rates annual...
Mapping the global intellectual landscape of inflammatory tumor microenvironment in colorectal cancer pathogenesis and prognostic research since this century [0.03%]
本世纪以来结直肠癌炎症型肿瘤微环境发病及预后研究的全球文献计量学分析
Hui Mu,Yushu Zhu,Feihu Yan et al.
Hui Mu et al.
Background: Colorectal cancer (CRC) is one of the most prevalent gastrointestinal tumors worldwide. Complex interactions between tumor microenvironment (TME) and host inflammatory response influence CRC progression and re...
Multiomics analysis of COL12A1 as a promising prognostic biomarker for immune-related treatment of gastric cancer [0.03%]
COL12A1的多组学分析及其作为胃癌免疫治疗预后生物标志物的潜力预测
Jin Shi,Chenggong Zhang,Zihao Gao et al.
Jin Shi et al.
COL12A1, a collagen type XII alpha 1 chain, has an instrumental role in the extracellular matrix (ECM), but its effect on gastric cancer (GC) and clinical significance remain unclear. In this study, co-expressed differentially expressed gen...
Integration of machine learning to reveal the correlation between ferroptosis and M2 macrophages in head and neck squamous cell carcinoma [0.03%]
机器学习在头颈鳞癌细胞中铁死亡与M2巨噬细胞相关性中的整合应用研究
Juntao Huang,Ziqian Xu,Lixin Cheng et al.
Juntao Huang et al.
Objective: To investigate the correlation between ferroptosis and M2 macrophages (M2Ms) in head and neck squamous cell carcinoma on the basis of multiomics data and machine learning methods. ...
Visualization and bibliometric analysis of global research trends on oral cancer screening and early diagnosis [0.03%]
全球口腔癌筛查和早期诊断研究趋势的可视化与文献计量分析
Guangcong Huang,Haojun Deng,Shuohui Sun et al.
Guangcong Huang et al.
Background: Cancer screening and early diagnosis play a crucial role in reducing the mortality of the late-stage oral cancer. This research performed bibliometric analysis of the published literature to provide an overvie...