Pan-cancer analysis of INHBA indicates its potential prognostic value and correlation with HNSC and LIHC [0.03%]
泛癌分析表明INHBA具有潜在的预后价值及其与头颈鳞状细胞癌和肝细胞癌的相关性
Shumin Li,Beibei Xu,Guanghui Wang et al.
Shumin Li et al.
Background: INHBA is a member of the TGF-β superfamily and is overexpressed in a variety of cancers and affects prognosis.However, its pan-cancer expression profile and specific roles in HNSC and LIHC remain poorly under...
A prognostic nomogram to predict clinical outcomes of patients with primary malignant and benign retroperitoneal tumors [0.03%]
预测原发性后腹膜恶性及良性肿瘤患者临床预后的列线图模型
Yunfei Zhang,Jing Wu,Abudusalamu Tuersunmaimaiti et al.
Yunfei Zhang et al.
Background: Primary retroperitoneal tumor (PRT) is a relatively rare tumor with diverse histological and molecular types. We aim to develop and validate a concise prognostic nomogram for patients with benign and malignant...
Clinicopathological characteristics of BRCA1-associated breast carcinoma patients in Kazakhstan [0.03%]
哈萨克斯坦BRCA1相关乳腺癌患者的临床病理特征分析
Ainur Samigatova,Nursulu Altaeva,Yerlan Suleimenov et al.
Ainur Samigatova et al.
Introduction: Breast cancer remains the leading cause of cancer-related mortality among women worldwide, including Kazakhstan. Germline mutations in the BRCA1 and BRCA2 genes play pivotal roles in the pathogenesis of brea...
The molecular aspects in prostatic cancer, unraveling the role of CDKs in prostate cancer progression [0.03%]
前列腺癌的分子特征及CDKs在前列腺癌进展中作用的研究
Zahra Farjami,Zahra Mohammadzadeh,Bita Saifi et al.
Zahra Farjami et al.
Background: Prostate cancer (PCa) is one of the leading causes of morbidity and mortality in the world, it becomes imperative to investigate the molecular mechanisms underlying practical therapeutic approaches. Cyclin-dep...
Ferroptosis and radiotherapy-related genes in head and neck squamous cell carcinoma: diagnostic and prognostic significance [0.03%]
铁死亡和放射治疗相关基因在头颈鳞状细胞癌中的诊断和预后价值
Liyuan Fan,Liang Shi,Zhongchao Wang et al.
Liyuan Fan et al.
Background: Head and Neck Squamous Cell Carcinoma (HNSCC) is an aggressive malignancy with poor prognosis and low five-year survival rates. Ferroptosis, an iron-dependent form of cell death, has emerged as a potential fac...
Blood expression of CTLA-4, PD-1, and PD-L1 as potential prognostic and diagnostic markers for breast cancer: a systematic review [0.03%]
CTLA-4、PD-1和PD-L1的血液表达作为乳腺癌预后及诊断标志物的系统综述研究
Mina Niusha,Saba Hajazimian,Nayemeh Soltani et al.
Mina Niusha et al.
The risk of developing cancer is significantly higher for individuals with compromised immune function, as the immune system plays a crucial role in defending the body against tumor cells. In the present study, we aimed to evaluate the bloo...
Emerging therapeutic advancements in pancreatic cancer: a contemporary review [0.03%]
胰腺癌的新兴治疗进展：当代综述
Midhun Malla,Yara Sakr,Garima Gupta et al.
Midhun Malla et al.
The escalating global burden of pancreatic ductal adenocarcinoma (PDAC) is imposing a critical health burden as a major cause of cancer-related mortality. Survival rates are low due to late-stage diagnosis and complex tumor microenvironment...
Inhibition of NR2F2 suppresses invasion ability and modulates EMT marker in head and neck squamous cell carcinoma [0.03%]
NR2F2抑制作用可抑制头颈鳞状细胞癌侵袭能力并调节上皮间质转化标志物表达水平
Joo Kyung Noh,Seon Rang Woo,Min Kyeong Lee et al.
Joo Kyung Noh et al.
The nuclear receptor subfamily 2 group F member 2 (NR2F2) has emerged as a potential therapeutic target in cancer due to its involvement in tumor progression, metastasis, angiogenesis, and epithelial-mesenchymal transition (EMT). However, i...
Suppressing CDCA8/CDK1 improves oral squamous cell carcinoma by modulating proliferation, apoptosis, cell cycle and migration [0.03%]
通过调节增殖、凋亡、细胞周期和迁移来抑制CDCA8 / CDK1可改善口腔鳞状细胞癌
Jiang Zhu,Chen Chu,Yu Xue et al.
Jiang Zhu et al.
We aimed to clarify the role of CDCA8/CDK1 in the progression of oral squamous cell carcinoma (OSCC) and the potential mechanisms. To explore the CDCA8 expression in OSCC, clinical samples were collected. In vitro, CAL-27 cells were transfe...
Development of an ADME gene signature for prognostic and therapeutic stratification in gastric cancer [0.03%]
胃癌预后和治疗分层的ADME基因特征的开发
Dandan Wang,Xuejian Wang,Lin Chen et al.
Dandan Wang et al.
A pivotal determinant of tumor therapy efficacy lies in the absorption, distribution, metabolism, and excretion (ADME) processes that govern drug disposition within the body. We intended to establish a prognostic model incorporating ADME-re...