Ultrasonic manifestations of intravascular leiomyomatosis involving the right atrium: a case report [0.03%]
右心房血管平滑肌瘤病的超声表现1例报告
Zhihong Su,Shunfa Huang
Zhihong Su
This case report describes a 37-year-old female with a history of cesarean section and uterine leiomyoma resection, who presented with recurrent dyspnea and palpitations. Echocardiography revealed a hyperechoic, mobile mass (3.9 × 2.2 cm) ...
Metastatic lung adenocarcinoma causes extensive destruction of the hip and pelvis [0.03%]
转移性肺腺癌导致髋部和骨盆广泛破坏
Wenjun Hao,Chaoquan Yang,Wenjun Liu et al.
Wenjun Hao et al.
Background: Lung cancer is the most prevalent tumor and frequently present with distant metastases, with the bone being one of the most common affected sites. However, bone metastases leading to complete resorption of the...
Constructing an ultrasound-assisted organoid model for tumor management [0.03%]
一种用于肿瘤治疗的超声辅助类器官模型构建方法
Tiantian Li,Xueying Wang,Miao Zhu et al.
Tiantian Li et al.
Organoids, an emerging bioengineering approach, can replicate the structure and function of human organs in vitro, providing valuable tools for biomedical research. Patient-derived organoids (PDOs) retain the histological and genetic charac...
The role of metabolites in the causal effect of immune cell phenotypes on immunotherapy toxicity risk [0.03%]
免疫细胞表型对免疫治疗毒性的因果作用中的代谢物的作用
Meng Tang,Fei Mu,Zhen Yan et al.
Meng Tang et al.
Background: Immune checkpoint inhibitors (ICIs) therapy have significantly improved survival in cancer patients. However, immune-related adverse events (irAEs) have emerged as a major challenge limiting its therapeutic ef...
Postbiotic-mediated gut microbiome modulation enhances R-CHOP efficacy in high-risk diffuse large B-cell lymphoma: a case report [0.03%]
一例高危弥漫性大B细胞淋巴瘤患者接受益生元治疗后R-CHOP疗效增强的病例报告
Xiujie Liu,Donghai Cheng,Fangyan Wang
Xiujie Liu
This case report describes an adult with high-risk DLBCL (IPI score 4) treated with R-CHOP combined with JK5G and JK21 postbiotics for gut microbiome modulation. The patient achieved significant tumor regression while maintaining stable hem...
CTHRC1/TGF-β/Smad axis serves as therapeutic targets in inhibiting oral squamous cell carcinoma by mediating ferroptosis [0.03%]
CTHRC1/TGF-β/Smad信号轴通过介导铁死亡抑制口腔鳞癌的治疗靶点作用
Shihao Huang,Yiming Jiao,Yongchun Chang et al.
Shihao Huang et al.
Background: Collagen triple helix repeat containing 1 (CTHRC1) is an oncogene in numerous human cancers including oral squamous cell carcinoma (OSCC). However, whether and how CTHRC1 influences OSCC progression through fe...
Nrf2 functions as a biomarker and therapeutic target in lung cancer based on bibliometric analysis and molecular mechanisms [0.03%]
基于文献计量分析和分子机制的 NRF2 在肺癌中的生物标志物和治疗靶点功能研究
Haixia Fan,Shudan Deng,Limantian Wang et al.
Haixia Fan et al.
Background: Lung cancer is one of the malignant tumors with high morbidity and mortality worldwide. Nuclear factor E2-ralated factor 2 (Nrf2), a critical antioxidant transcription factor, has been identified to play a sig...
Pengge Lu,Zhaohui Wang
Pengge Lu
Colorectal cancer (CRC) remains a prevalent global malignancy with increasing incidence. This review systematically explores the intricate and often paradoxical dual roles of lipid metabolism components-triglycerides, cholesterol, HDL-C, an...
Integration analysis of single-cell and spatial transcriptomics identifies prognostic genes associated with neddylation in colorectal cancer [0.03%]
单细胞和空间转录组集成分析识别出与结直肠癌预后相关的泛素偶联途径候选基因
Ziming Zhu,Xinyue Zhang,Song Wang et al.
Ziming Zhu et al.
Background: Neddylation modifications in immune and tumor cells are linked to poor tumor prognosis. This study identifies prognostic genes associated with neddylation-related genes (NRGs) in colorectal cancer (CRC) using ...
Targeting NADPH oxidase 2 suppresses the growth of esophageal squamous cell carcinoma by regulating BTG2 pathway [0.03%]
靶向NADPH氧化酶2通过调节BTG2通路抑制食管鳞癌生长
Xiao-Jie Liu,Can-Lin Yang,Yun-Lei Zhang et al.
Xiao-Jie Liu et al.
Background: Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 (NOX2) plays a carcinogenic role in various tumors. Recent study has reported that the carcinogenic mechanism of NOX2 in esophageal squamous cell c...