Training and validation of a 1D CNN model for accurate three-class classification of oral cancer using serum Raman spectroscopy [0.03%]
基于血液拉曼光谱训练和验证口腔癌三分类的1D卷积神经网络模型
Mukta Sharma,Shiang-Fu Huang
Mukta Sharma
In this study, a one-dimensional convolutional neural network (1D-CNN) was developed for classifying serum Raman spectra into three oral cancer-related classes: normal, precancerous, and cancerous. To address class imbalance, class-weighted...
Overexpression of TREM1 predicts poor prognosis and chemotherapy resistance in Egyptian acute myeloid leukemia associated with FLT3 internal tandem duplication and CD123 expression and stemness signatures [0.03%]
TREM1过表达预测不良预后及化疗耐药在埃及急性髓系白血病患者中的相关性，伴有FLT3内部串联重复、CD123表达和干细胞特征标志物
Shima Gafar Mansor,Rasha Elgamal,Mostafa F Mohammed Saleh et al.
Shima Gafar Mansor et al.
Background: Despite advances, over half of AML patients relapse or become refractory to chemotherapy. TREM1 (CD354), a regulator of tumor inflammation and immune evasion in solid cancers, remains poorly characterized in A...
The role of extracellular vesicles-associated proteins markers in prostate cancer: a review [0.03%]
前列腺癌中细胞外囊泡相关蛋白质标志物的作用：综述
Diana Suhaiza Said,Muhammad Nazrul Hakim Abdullah,Armania Nurdin
Diana Suhaiza Said
Prostate cancer (PCa) is in the top three most common cancers among the world's male population, and its incidence has been increasing over the years. However, the primary screening and diagnostic tools still rely on serum prostate-specific...
A bibliometric analysis of optogenetics in cancer research based on the web of science core collection [0.03%]
基于Web of Science核心合集的光遗传学在癌症研究中应用的文献计量分析
Yulai Yin,Yang Jiang,Shuo Gong et al.
Yulai Yin et al.
Objective: To conduct a bibliometric analysis of the research literature on optogenetics in the field of cancer. Methods: A literature ...
Novel cuproptosis related long non-coding RNA signature in oral squamous cell carcinoma prognosis and immunotherapy [0.03%]
新的铜死亡相关长链非编码RNA在口腔鳞状细胞癌预后及免疫治疗中的作用签名
Subhayan Sur
Subhayan Sur
Cuproptosis, a recently identified copper-dependent regulated cell death, is increasingly recognized for its relevance in cancer biology. In their study, Kong L et al. have developed a four long non-coding RNA (lncRNA) cuproptosis-related p...
Mendelian randomization analysis of causal relationships between chondrosarcoma and angiogenesis related genes [0.03%]
卡瑞诺玛与血管生成相关基因间的梅德尼恩随机分析因果关系研究
Peng Xie,Xiangtao Bian,Wei Wei et al.
Peng Xie et al.
Objective: To systematically explore causal relationships between chondrosarcoma and angiogenesis-related gene expression using Mendelian randomization (MR) and transcriptome-wide association study (TWAS) approaches, and ...
SNARE proteins as biomarkers and therapeutic targets in central nervous system tumors [0.03%]
SNARE蛋白作为中枢神经系统肿瘤的生物标志物和治疗靶点
Dengzhuo Liu,Jie Li,Zihao Fan et al.
Dengzhuo Liu et al.
Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins constitute the core molecular machinery that drives intracellular vesicular trafficking and membrane fusion in eukaryotic cells. Beyond their canonical r...
Orlistat potentiates the gemcitabine effect in inhibiting the malignant biological behavior of nasopharyngeal carcinoma by downregulating PKM2 [0.03%]
奥利司他通过下调PKM2增强吉西他滨抑制鼻咽癌恶性生物学行为的作用
Peishan Zhang,Qinfang Cai,Shaoji Ouyang
Peishan Zhang
Background: Gemcitabine (GEM)-based chemotherapy is essential for treating recurrent or metastatic nasopharyngeal carcinoma (NPC). However, the limited sensitivity, coupled with the associated toxicities and side effects,...
Potential diagnostic, prognostic, and therapeutic implications of ferroptosis in myelodysplastic syndromes [0.03%]
铁死亡在骨髓增生异常综合征中的潜在诊断、预后和治疗意义
Muluken Walle,Fasil Getu,Bisrat Birke Teketelew et al.
Muluken Walle et al.
Myelodysplastic syndromes (MDS) are a heterogeneous group of malignant disorders originating from hematopoietic stem cells. Ineffective hematopoiesis, peripheral blood cytopenia, immune disorder, and a high risk of progression to acute myel...
Allicin inhibits colon cancer cells biological activity by regulating lncRNA UCA1 via autophagy stimulating [0.03%]
大蒜素通过诱导自噬调控长链非编码RNA UCA1抑制结肠癌细胞活性
Guoying Zhang,Zhongkui Lu,Xintong Dou et al.
Guoying Zhang et al.
Objective: This study aimed to investigate the mechanism by which allicin, a bioactive compound from garlic, exerts antitumor effects, specifically focusing on its role in regulating the long non-coding RNA UCA1 via the i...