LncRNA NEAT1 modulates myeloma cell autophagy and apoptosis by competitively binding miR-195-5p to regulate CEBPA [0.03%]
长链非编码RNA NEAT1通过竞争性结合miR-195-5p调节CEBPA来调控多发性骨髓瘤细胞自噬和凋亡
Ting Wang,Hongyue Xu,Wei Tao et al.
Ting Wang et al.
Objective: This study explores the molecular mechanism by which lncRNA NEAT1 modulates the expression of the transcription factor CEBPA through competitive binding with miR-195-5p, thereby influencing multiple myeloma (MM...
Retraction Note: Identifying therapeutic target for prostate cancer: exploring Diosmetin as a CYP inhibitor [0.03%]
撤回 notice:鉴定治疗前列腺癌的治疗靶点：研究 diosmetin 的 cyp 抑制剂作用
Mohammad Habibur Rahman Molla,Mohammed Othman Aljahdali
Mohammad Habibur Rahman Molla
Identification of biomarkers related to the progression of cutaneous melanoma and construction of survival prognosis model [0.03%]
黑色素瘤进展相关生物标志物的识别及生存预测模型的构建
Kana Chen,Wei Ye,Longjun Chi et al.
Kana Chen et al.
Background: Under certain circumstances, nevi may undergo malignant transformation into skin cutaneous melanoma (SKCM), which is a highly aggressive and deadly malignant tumor originating from melanocytes. Early identific...
Re-sensitization of cancer multidrug resistance through P-gp, MRP1 and BCRP modulation: advances in terpenoids based cancer therapy [0.03%]
基于萜类的癌症治疗中通过P-糖蛋白、MRP1和BCRP调节克服癌多药耐药的研究进展
Pratibha Pandey,Ajay Singh,Sorabh Lakhanpal et al.
Pratibha Pandey et al.
Among the most significant risks that many chemotherapeutic drugs currently encounter is the development of multidrug resistance (MDR) in cancerous cells. Numerous critical regulators are thought to be responsible for MDR and render therape...
Unveiling the expression and mechanistic role of SYCP2 in cervical lesions [0.03%]
SYCP2在宫颈病变中的表达及功能机制研究
Yuanhang Zhu,Zhongchen Hou,Chunli Wang et al.
Yuanhang Zhu et al.
Background: Persistent HPV infection is the primary cause of cervical carcinogenesis. While HPV testing as a screening modality has reduced cervical cancer incidence, standalone HPV screening cannot distinguish persistent...
Intracavitary infusion of FOLactis Lactobacillus leads to disappearance of MPE in patient with advanced lung adenocarcinoma [0.03%]
一例晚期肺腺癌患者腹腔内输注FOLactis乳酸菌后恶性腹水消失
Mingzhen Zhou,Juan Zhang,Sihui Zhu et al.
Mingzhen Zhou et al.
This case report presents the application of FOLactis, a lactic acid bacterium in situ vaccine, in the treatment of a lung adenocarcinoma patient who presented with malignant pleural effusion (MPE). An adult patient diagnosed with lung aden...
Mendelian randomization analysis: causal link between hyperthyroidism/thyrotoxicosis and ovarian cancer [0.03%]
孟德尔随机化分析：甲状腺功能亢进/毒性与卵巢癌之间的因果联系
Hong Wang,Caijuan Liang,Yanqiu Yu et al.
Hong Wang et al.
Background: The purpose of this study was to use a two-sample Mendelian randomization (MR) approach to explore the causal link between hyperthyroidism/thyrotoxicosis and ovarian cancer (OC). ...
The bidirectional regulatory effects of bacteria on blood vessels in the tumor microenvironment [0.03%]
肿瘤微环境内细菌对血管的双向调节效应
Wei Peng,Xiaomei Huang,Yinquan Pu et al.
Wei Peng et al.
The diagnosis and treatment of tumors represent significant global challenges. Understanding the tumor microenvironment (TME) is crucial for a more comprehensive understanding of the mechanisms of tumorigenesis. The TME is a dynamic and com...
Fibrinogen beta chain as a prognostic biomarker and therapeutic target in tobacco-associated lung adenocarcinoma [0.03%]
纤溶原β链作为烟草相关肺腺癌预后生物标志物和治疗靶点的潜在作用
Jijun Xue,Wenfeng Han,Wentao Zhao et al.
Jijun Xue et al.
The β-subunit of fibrinogen (FGB), a key element of the main plasma clotting protein, is increasingly recognised as a contributor to tumour biology. To clarify its relevance in smoking-related lung adenocarcinoma (LUAD), we interrogated se...
Elevated NUF2 and CD52 expression predict platinum-based chemoresistance and poor prognosis in non-small cell lung cancer [0.03%]
NUF2和CD52高表达预示非小细胞肺癌患者对以铂类为基础的化疗耐药及预后不良
Bo Liu,Zhansheng Lu,Jing Yao
Bo Liu
Objective: This study aimed to explore the clinical significance of the cytokinesis-associated gene NUF2 and the immune-related gene CD52 in non-small cell lung cancer (NSCLC), with a focus on their association with plati...