rs604702 confers breast cancer risk by influencing PCAT18/miR-759/SPRR3 axis [0.03%]
rs604702通过影响PCAT18/miR-759/SPRR3轴赋予乳腺癌易感性
Xin-Xin Zhang,Ya-Jie Li,Xi-Ting Zhou et al.
Xin-Xin Zhang et al.
Breast cancer is the most common tumor type in women and with apparent genetic predisposition. Recent genome-wide association study suggests that rs527616 is significantly associated with this disease. Analysis on 1000 genomes project data ...
Prognostic significance of dipeptidyl peptidase-7 (DPP7) in HPV16-negative head and neck squamous cell carcinoma treated with induction chemoradiotherapy [0.03%]
DPP7在HPV16阴性下咽喉鳞癌诱导化学放射治疗中的预后价值
Amal F Gharib,Haytham Dahlawi,Shereen El Tarhouny et al.
Amal F Gharib et al.
Background: Head and neck squamous cell carcinoma (HNSCC) significantly impairs critical functions such as speech, swallowing, and breathing, often resulting in disfigurement and a substantial decline in quality of life. ...
Aurora Kinase A inhibitor alisertib failed to exert its efficacy on TNBC cells due to consequential enrichment of polyploid giant cancer cells (PGCCs) [0.03%]
AurKA抑制剂阿利昔替布通过诱导多倍体巨癌细胞的积累而不能对TNBC细胞产生药效学作用
Debanjan Thakur,Debomita Sengupta,Shinjini Kar et al.
Debanjan Thakur et al.
Background: Kinases are emerging as promising targetable choices for Triple negative breast cancer (TNBC) patients who suffer from lack of targeted therapy. Aurora kinase A (AURKA) inhibitor alisertib although showed prom...
Global trend and geographic distribution of thyroid cancer from 1990 to 2021 and its prediction until 2030 [0.03%]
1990年至2021年全球甲状腺癌流行趋势及地理分布及其2030年前的预测分布地图
Zahra Maleki,Jafar Hassanzadeh,Mohammad Aryaie et al.
Zahra Maleki et al.
Background: This study aimed to determine global thyroid cancer incidence and mortality trends from 1990 to 2021 and their projections for 2030. Methods: ...
Global research dynamics in metabolic biomarkers and cancer: a bibliometric study from 2015 to 2025 [0.03%]
2015—2025年代谢标志物与癌症的全球研究动态分析——文献计量学研究
Longtao Zhang,Yanxiao Sun,Yuxia Ma
Longtao Zhang
Objective: Metabolic biomarkers are important for the early detection and prognostic assessment of cancer. Nevertheless, a bibliometric analysis examining their research landscape within this domain has not been performed...
Spatial transcriptomic landscape and cellular neighborhood heterogeneity in cervical cancer: integrative single-cell and spatial RNA sequencing analysis [0.03%]
宫颈癌的空间转录组景观及细胞异质性：整合单细胞和空间转录组分析
Dieyi Mo,Huana Cao,Shaojuan Lai et al.
Dieyi Mo et al.
Background: Cervical cancer ranks as the fourth most common malignancy among women worldwide, with approximately 604,000 new cases and 342,000 deaths annually. Despite advances in HPV vaccination and screening programs, s...
The Reg gene family: roles in gastric and colorectal cancer progression and its potential for targeted therapy [0.03%]
Reg基因家族在胃癌和结直肠癌进展中的作用及其作为靶向治疗的潜力
Fei Liao,Xun Xiao
Fei Liao
The management of human malignancies presents ongoing challenges in modern medicine, particularly given the high morbidity and mortality associated with gastrointestinal cancers. Despite advances in therapeutic strategies, tumor complexity ...
The role and application potential of cytochrome c in breast cancer therapy [0.03%]
细胞色素c在乳腺癌治疗中的作用及应用潜力
Hongshuang Yue,Yumei Fu,Xiuyue Fan et al.
Hongshuang Yue et al.
Apoptosis plays an important role in all stages of normal breast development, including duct morphogenesis, lactation and proliferative regression. Abnormal apoptosis of breast cells leads to the occurrence of tumors. Studies have shown tha...
PLOD1 promotes gastric cancer metastasis and immune escape by mediating extracellular matrix remodeling [0.03%]
PLOD1通过介导细胞外基质重塑促进胃癌转移和免疫逃逸
Yinkui Chen,Xing Wu
Yinkui Chen
Background: Procollagen-lysine 2-oxoglutarate 5-dioxygenase 1 (PLOD1) is important for extracellular matrix formation and is involved in a variety of diseases, including cancer; however, its role in gastric cancer (GC) re...
Causal relationship between oral/gut microbiota and lung cancer: a two-sample Mendelian randomization study [0.03%]
口腔/肠道微生物与肺癌的因果关系：两项样本孟德尔随机化研究
Zi-Jian Huang,Lv Wu,Ying-Long Peng et al.
Zi-Jian Huang et al.
Purpose: Several studies have already proven a significant correlation between the microbiota and lung cancer. In this study, we explore the potential relative oral and gut microbiota which influence the risk of lung canc...