Characterization, expression, and mutational analysis of endosomal protein lethal giant disc (Lgd/CC2D1A) as a biomarker in patients with T-cell acute lymphoblastic leukemia [0.03%]
致命巨大型(endosomal蛋白lgd/cc2d1a)的特征、表达和突变分析及其在T细胞急性淋巴细胞白血病患者中的生物标记物研究
Sandeep Pandey,Ranjana Singh,Nimra Habib et al.
Sandeep Pandey et al.
Background: The endosomal pathway plays a crucial role in eukaryotes, and its conservation across evolution underscores its importance in fundamental processes, such as endocytosis, cytokinesis, and autophagy. Dysregulati...
Research on the interactive mechanisms between mitochondrial variations and immune responses in gliomas based on integrated visualization analysis [0.03%]
基于综合可视化分析的胶质瘤线粒体变异与免疫反应互作机制研究
Shiwang Li,E Lu,Lin Mi et al.
Shiwang Li et al.
Gliomas, as the most invasive primary malignant tumors of the central nervous system, exhibit a significant correlation between their pathological features and clinical prognosis. Among them, glioblastoma multiforme (GBM) is classified as a...
A robust EMT-related prognostic model for ccRCC integrating single-cell and bulk transcriptome data [0.03%]
结合单细胞和批量转录组数据的ccRCC相关EMT预后模型
Zhiyu Yin,Zijian Ye,Zhengbin Li et al.
Zhiyu Yin et al.
A comprehensive bibliometric and visual analysis of tumor-associated macrophages in hepatocellular carcinoma [0.03%]
肝细胞癌相关巨噬细胞的全面文献计量和可视化分析
GuanBo Zhang,Gang Li,JinSong Li et al.
GuanBo Zhang et al.
Extracellular vesicle-enclosed microRNAs serve as non-invasive biomarkers in the major upper and lower gastrointestinal tract tumors: a bibliometric analysis (2010-2025) [0.03%]
外泌体微小核糖核酸作为消化道肿瘤非侵入性标志物的文献计量学分析（2010-2025）
Guanlan Zhang,Jincheng Li,Jingwen Ling et al.
Guanlan Zhang et al.
Background: Gastrointestinal tract (GIT) tumors account for a large global cancer burden, partly due to the lack of efficient non-invasive early detection biomarkers. For microRNAs (miRNAs) can stably circulate in body fl...
Pan-cancer multi-omics analysis reveals IQCE as a malignant cell-restricted oncogenic biomarker driving immunosuppression and chemoresistance in cutaneous melanoma [0.03%]
泛癌种多组学分析揭示IQCE是恶性黑色素瘤免疫抑制和化疗耐药的癌基因标志物
Qing Luo,Jingya Wang,Ting Chen et al.
Qing Luo et al.
Background: Cutaneous melanoma (SKCM) presents significant therapeutic challenges due to heterogeneity and acquired resistance to targeted and immune checkpoint blockade therapies. IQCE, a ciliary scaffold protein, has po...
A global bibliometric perspective on autophagy and tumor microenvironment in cancer research [0.03%]
从文献计量学角度分析癌症研究中自噬及肿瘤微环境的全球视角
Ishita Debnath,Moumita Kundu
Ishita Debnath
Background: Autophagy plays a key role in cell recycling and also has a double-edged sword role in cancer. It serves as a tumor suppressor in the initial phases but eventually maintains stress resistance in cancer cells. ...
iRGD-modified co-loaded curcumin piperine liposomes inhibit angiogenesis in non-small cell lung cancer through the VEGFR2/P38/MK2 signaling axis [0.03%]
iRGD修饰的姜黄素胡椒碱共载脂质体通过VEGFR2/P38/MK2信号轴抑制非小细胞肺癌新生血管形成
Xunhua Huang,Yongzhong Chen,Jiayuan Chen et al.
Xunhua Huang et al.
Background: In our previous study, we provided evidence that iRGD-modified co-loaded curcumin piperine liposomes (iRGD-LP-CUR-PIP) have in vitro and in vivo anti-non-small cell lung cancer (NSCLC) activity. However, the m...
Peiminine suppresses prostate cancer progression by regulating cell proliferation, motility, apoptosis, and mitochondrial dysfunction [0.03%]
皮美宁通过调节细胞增殖、运动性、凋亡和线粒体功能障碍来抑制前列腺癌进展
Yang Yu,Xiaobo Chen,Fei Xiong
Yang Yu
Background: Peiminine, an active alkaloid, has been reported to exhibit antitumor properties in several malignancies. This study aims to examine the role and potential mechanism of peiminine in prostate cancer (PCa). ...
Metformin's multifaceted role in colorectal cancer: mechanisms of action and synergy with standard treatments [0.03%]
二甲双胍在结直肠癌中的多重作用：作用机制与标准治疗的协同效应
Haniye Rahimi Kolour,Nastaran Bahrami,Ehsan Nazemalhosseini-Mojarad et al.
Haniye Rahimi Kolour et al.
Despite advancements in treatment, colorectal cancer (CRC) prevalence, mortality rates, and therapeutic resistance persist as global health concerns. The review delves into metformin's multifaceted effects on molecular pathways implicated i...