Unveiling oncogene-induced senescence: a new frontier in prostate cancer prognosis and therapy [0.03%]
揭开致癌基因诱导的衰老之谜：前列腺癌预后和治疗的新前沿
YunZhen Peng,Xin Qiu,JunJie Cai et al.
YunZhen Peng et al.
Background: Prostate cancer (PCa) is the most common tumor in the male urogenital system. Radical prostatectomy, radiation, chemotherapy and endocrine therapy are common clinical treatment methods. Oncogene-induced senesc...
Molecular mechanisms and genetic predisposition to osteoarthritis and osteosarcoma through Mendelian inheritance patterns [0.03%]
通过孟德尔遗传模式的分子机制和遗传易感性导致骨关节炎和骨肉瘤
Hao Fei,Wen Huang,Yueyuan Chen et al.
Hao Fei et al.
Background: Osteoarthritis and osteosarcoma are important orthopedic diseases whose genetic susceptibility and molecular mechanisms require further investigation. This study aims to systematically analyze the genetic vari...
Publisher Correction: An oxidative stress related gene signature predicts prognosis in cholangiocarcinoma [0.03%]
Publisher Correction：与氧化应激相关的基因特征可预测胆管癌预后
Han Fan,Peng Qiu,Yun Lu et al.
Han Fan et al.
Published Erratum
Discover oncology. 2025 Nov 12;16(1):2082. DOI:10.1007/s12672-025-03463-6 2025
Lablab purpureus bioactive fractions as potent anticancer agents: an in vitro and in Silico study [0.03%]
刀豆属纯紫色生物活性组分作为潜在的抗癌剂：体外和分子对接研究
Smitha S Bhat,Sushma Jahagirdar,Sarana Rose Sommano et al.
Smitha S Bhat et al.
Background: Plant-based bioactive compounds are essential for the discovery of drugs, especially in cancer research, because they include a wide range of chemicals and are very specific to certain types of cells. In earli...
Case report of curative resection after preoperative bevacizumab and sintilimab therapy in hepatocellular carcinoma with lymph node metastasis [0.03%]
贝伐珠单抗和信迪利单抗新辅助治疗后实现根治性手术切除的肝癌伴淋巴结转移病例报告
Shujie Pang,Yingcheng Yang,Zhe Sun et al.
Shujie Pang et al.
Hepatocellular carcinoma with lymph node metastasis (HCC-LNM) is relatively rare, and optimal management remains controversial. We report two cases of HCC with lymph node metastasis treated with three cycles of Sintilimab and Bevacizumab th...
Plasma proteins and osteosarcoma risk: causal evidence from Mendelian randomization [0.03%]
基于孟德尔随机化对血浆蛋白与骨肉瘤风险因果关系的证据研究
Hanjun Ma,Ju Liao,Zonglong He et al.
Hanjun Ma et al.
Osteosarcoma (OS) is an exceptionally aggressive bone cancer, and the identification of blood-based biomarkers for early detection and prognosis remains a significant challenge. This study aimed to investigate the causal relationships betwe...
CPZ promotes the proliferation of gastric cancer by activating the Wnt pathway through binding with DVL2 [0.03%]
CPZ通过与DVL2结合激活Wnt信号通路促进胃癌细胞增殖
Rongkui Luo,Wen Huang,Huimei Wang et al.
Rongkui Luo et al.
Background: Gastric cancer (GC) is one of the most prevalent and heterogeneous malignancies worldwide, with treatment outcomes often hindered by delayed diagnosis and limited therapeutic options. Consequently, identifying...
Global research landscapes of ALDH2 and cancer revealed by bibliometric analysis [0.03%]
基于文献计量分析的ALDH2和癌症全球研究图谱
Tongtong Zhang,Xiaodong Chen,Wenjie Yu et al.
Tongtong Zhang et al.
Recent years have seen a marked increase in studies focusing on the mechanistic role of Aldehyde dehydrogenase 2 (ALDH2) genetic polymorphisms in tumors, yet this field lacks systematic bibliometric analysis. By analyzing publication years,...
Development of machine learning models for survival prediction in nasopharyngeal carcinoma using population-based data [0.03%]
基于人口统计数据的鼻咽癌患者生存预测机器学习模型的研究与开发
Guoxiang Lin,Qiyan Mo,Lu Han et al.
Guoxiang Lin et al.
Background: Despite significant improvements in treatment efficacy, nasopharyngeal carcinoma (NPC) remains one of the most common and threatening head and neck cancers. This study sought to build a risk stratification mod...
Single-cell hdWGCNA identifies ICI-related-colitis key CD8 + T cells linked to immunotherapy response and prognosis in colon cancer [0.03%]
单细胞hdWGCNA识别ICI相关性结肠炎关键CD8+T细胞与结直肠癌免疫治疗反应和预后的关系
Shuiqing Wu,Wenxuan Tang,Shaocong Mo et al.
Shuiqing Wu et al.
Background: In recent years, immune checkpoint inhibition therapy has brought hope for the treatment of malignancies. However, it can also lead to adverse reactions due to excessive immune activation, with checkpoint inhi...