Serum miR-200c-3p and miR-6134 as diagnostic biomarkers for epithelial ovarian cancer [0.03%]
血清miR-200c-3p和miR-6134作为上皮性卵巢癌诊断生物标志物
Rina Kawahara,Eiji Nishio,Aya Iwata et al.
Rina Kawahara et al.
Background: MicroRNAs (miRNAs) regulate gene expression and are emerging as biomarkers for epithelial ovarian cancer (EOC). We evaluated the diagnostic performance of serum miR-200c-3p and miR-6134, alone and in combinati...
Primary tumor resection improves survival in colon cancer patients with unresectable liver only metastases [0.03%]
结肠癌肝转移患者原发肿瘤切除改善生存率
Yunbin Ma,Wenguo Yang,Jialin Chen et al.
Yunbin Ma et al.
Background: The optimal management of colon cancer patients with unresectable liver-only metastases remains controversial. This study aimed to evaluate whether primary tumor resection confers a survival benefit in this po...
Designing a web-based platform for dynamic estimation of individualized conditional survival in grade 3 gliomas [0.03%]
设计基于网络的平台 动态估计三级胶质瘤个体化条件生存率
Zhihao Yang,Regina Chizi Tunje,Jiajie Xia et al.
Zhihao Yang et al.
Background: Grade 3 gliomas, including anaplastic astrocytoma and anaplastic oligodendroglioma, are aggressive brain tumors with heterogeneous prognoses. Existing survival models often fail to account for time-dependent c...
Research trends and hotspots of Lamin family in cancer: a bibliometric analysis [0.03%]
癌基因Lamin家族研究趋势及热点分析——基于文献计量学的视角
Fang Liu,Min Wang,Tian Zhu et al.
Fang Liu et al.
Objectives: This study aims to use bibliometrics to visually analyze the role of the Lamin family in cancer, clarify the current research status, and determine research hotspots and future directions. ...
Real-world comparison of doxorubicin-ifosfamide versus gemcitabine-docetaxel regimens in metastatic uterine leiomyosarcoma: a multicenter retrospective study [0.03%]
多中心回顾性研究比较转移性子宫平滑肌肉瘤的多柔比星-异环磷酰胺与吉西他滨-多西他赛方案疗效
Salih Tunbekici,Gokhan Sahin,Haydar Cagatay Yuksel et al.
Salih Tunbekici et al.
Background: Uterine leiomyosarcoma is a rare and aggressive malignancy with limited responsiveness to standard therapies. We conducted a real-world, multicenter study to compare the clinical efficacy and safety of two com...
Manisha Shukla,Poorna Shri,Sunil Kumar Mahobiya et al.
Manisha Shukla et al.
Metastatic cancer remains the leading cause of cancer-related mortality, largely owing to the limitations of conventional treatments such as chemotherapy, radiotherapy, and targeted agents that are challenged by tumor heterogeneity, acquire...
Integrative Mendelian randomization and spatial transcriptomics analysis reveals causal links between plasma lipidome and non-small cell lung cancer [0.03%]
整合性孟德尔随机化和空间转录组学分析揭示了血浆脂质组与非小细胞肺癌之间的因果关系
Baiquan Zhang,Jintao Liu,Qian Guo et al.
Baiquan Zhang et al.
Background: This study aimed to investigate the potential causal relationship between plasma lipidome and non-small cell lung cancer (NSCLC) using a two-sample Mendelian randomization (MR) approach based on large-scale ge...
Intracranial undifferentiated pleomorphic sarcoma of right frontal lobe: a case report [0.03%]
右侧额叶未分化的弥漫性肉瘤一例报告
Yulong Deng,Yueqiao Deng,Lurong Li et al.
Yulong Deng et al.
Background: Intracranial undifferentiated pleomorphic sarcoma (UPS) is extremely rare and mostly seen among the middle-aged people. The patients are asymptomatic or have atypical manifestations such as headaches and seizu...
Exploration of the roles of CAFs in melanoma based on single-cell transcriptomics and spatial transcriptomics [0.03%]
基于单细胞和空间转录组学探究肿瘤相关成纤维细胞在黑色素瘤中的作用
Sheng Hong,Yuhan Zhao,Anni Hu et al.
Sheng Hong et al.
Background: Cancer-associated fibroblasts (CAFs) are increasingly recognized as critical contributors to the limited efficacy of immunotherapy, particularly through the establishment of immune-excluded tumor microenvironm...
Decoding breast cancer: insights into molecular pathways & therapeutic approaches [0.03%]
解码乳腺癌：分子通路和治疗途径的洞见
Tanjima Tarique Laskar,Hasina Mehnaj Laskar,Jiaul Ahmed Mazumder et al.
Tanjima Tarique Laskar et al.
Breast cancer is a highly heterogeneous malignancy encompassing distinct molecular subtypes such as Luminal A & B, HER2 enriched and triple negative breast cancer, each characterized by unique genomic, transcriptomic and proteomic landscape...