High expression of GRB14 is associated with cancer progression and poor prognosis in gastric cancer [0.03%]
GRB14高表达与胃癌进展和预后不良相关
Haijie Hu,Xiaomin Feng,Yuxiu Zou et al.
Haijie Hu et al.
Background: Growth factor receptor-bound protein 14 (GRB14) has emerged as a significant regulator in cancer progression and prognosis across certain cancer types. Nevertheless, its role in gastric cancer (GC) remain poor...
Anti-Müllerian hormone plays a bidirectional role in cancer: a multi-database and multi-method study [0.03%]
抗穆勒管激素在癌症中发挥双向作用：多数据库和多方法研究
Yanan Wang,Zirui Xi,Yuzheng Peng et al.
Yanan Wang et al.
Introduction: Anti-Müllerian hormone (AMH) has been variably associated with cancer risk. This study integrated a meta-analysis, Mendelian randomization (MR), and transcriptomic analyses to clarify the relationship betwe...
Applications of bioluminescence-mediated photodynamic therapy (BL-PDT) for the treatment of deep-seated tumours [0.03%]
用于治疗深部肿瘤的生物发光介导光动力疗法(BL-PDT)的应用研究
Mpho Mohlongo,Blassan P George,Heidi Abrahamse
Mpho Mohlongo
Bioluminescence, the light generated through biochemical reactions involving luciferases in living organisms, has been the focus of extensive research due to its diverse applications. It is especially noteworthy as an internal light source ...
Development and validation of an AI-augmented deep learning model for survival prediction in de novo metastatic colorectal cancer [0.03%]
人工智能增强的深度学习模型在初诊转移性结直肠癌生存预测中的开发和验证
Merih Yalçıner,Efe Cem Erdat,Engin Eren Kavak et al.
Merih Yalçıner et al.
Purpose: Accurate prognostication in metastatic colorectal cancer (mCRC) remains challenging due to disease heterogeneity. This study aimed to develop and validate an artificial intelligence-augmented deep learning model ...
TKI resistance related genes in LUAD predict patient prognosis and tumor immune microenvironment with LHX2 as a hub gene [0.03%]
LUAD中与EGFR-TKI耐药相关的基因通过肿瘤免疫微环境预测患者预后且LHX2是核心基因
Ruohan Huang,Qi Liang,Hongya Wang et al.
Ruohan Huang et al.
Background: Non-small cell lung cancer (NSCLC), particularly lung adenocarcinoma (LUAD), is a leading cause of cancer-related mortality. Osimertinib, a third-generation epidermal growth factor receptor-tyrosine kinase inh...
CD5+ primary hepatosplenic large B-cell lymphoma and rhupus syndrome in a patient: a case of concurrent diagnosis? [0.03%]
一例患者并发肝脾大B细胞淋巴瘤和RhUPUS综合征的诊断？
Shujun Lin,Jun Yin,Zewen Zhang et al.
Shujun Lin et al.
CD5+ primary hepatosplenic large B-cell lymphoma (LBCL) is an infrequent disease (Shi et al. in J Int Med Res 48(8):1220737725, 2020; Yamaguchi et al. in Blood 99(3):815-821, 2002; Durani et al. in Leuk Lymphoma 62(13):3078-3086, 2021). Rhu...
Induction chemotherapy followed by definitive chemoradiation in patients with inoperable esophageal squamous cell carcinoma: a multicenter retrospective study [0.03%]
新斯的明联合麻碱治疗术后腹胀的疗效观察
Taha Koray Sahin,Imdat Eroglu,Ismail Dilli et al.
Taha Koray Sahin et al.
Background: Esophageal squamous cell carcinoma (ESCC) remains a global health challenge, characterized by significant geographic variations in incidence, risk factors, and treatment paradigms. While definitive chemoradiot...
Expression of ITGA3 in pan-cancer tissues and its relationship to prognosis and immune infiltration [0.03%]
ITGA3在泛癌组织中的表达及其与预后和免疫浸润的关系
Zidi Zhang,Mengjun Zhang,Hongyang Liu et al.
Zidi Zhang et al.
Cancer constitutes a significant global health challenge, contributing to escalating socioeconomic burdens and necessitating the urgent identification of novel biomarkers and therapeutic targets. This study seeks to investigate the expressi...
MISP promotes the progression of lung adenocarcinoma through Inhibition of the Hippo signaling pathway [0.03%]
MISP通过抑制Hippo信号通路促进肺腺癌进展
Yuanjun Cheng,Yumei Shen,Wei Fang et al.
Yuanjun Cheng et al.
Background: Globally, lung cancer is a malignant tumor with the highest morbidity and mortality rate, of which lung adenocarcinoma (LUAD) is the most common pathological type, accounting for about 40% of all cases. This s...
SGLT2 inhibitors and their role in reducing mortality among cancer patients with type 2 diabetes undergoing immune checkpoint inhibitor therapy [0.03%]
SGLT2抑制剂在降低2型糖尿病癌症患者免疫检查点抑制剂治疗过程中死亡率的作用
Fabiana Lucà,Iris Parrini
Fabiana Lucà
Patients with type 2 diabetes mellitus (T2DM) and cancer undergoing immune checkpoint inhibitor (ICI) therapy face increased risks due to the convergence of metabolic, cardiovascular, and immune-related complications. Recent retrospective d...