Charting the landscape and evolution of research on cell death in acute lymphoblastic leukemia: a comprehensive bibliometric analysis (1990-2024) [0.03%]
急性淋巴细胞白血病细胞死亡研究的景观和进化：1990-2024年的全面文献计量分析
Shen Wang,Xuhan Zhang,Zhang
Shen Wang
Background: The interplay between regulated cell death pathways and Acute Lymphoblastic Leukemia (ALL) pathobiology profoundly influences disease progression and therapeutic responses. ...
Exploring ASPN as a pan-cancer biomarker with a focus on gastric cancer [0.03%]
ASPN作为泛癌症生物标志物（以胃癌为重点）的探索研究
Yue Feng,Sijiang Zhou,Bing Yang et al.
Yue Feng et al.
Background: Cancer remains a leading cause of mortality worldwide, posing a serious threat to public health. The ASPN protein has emerged as a key player in certain cancers; however, its precise mechanisms and regulatory ...
Integrated machine learning and causal inference reveal CHRDL1 as a diagnostic and functional biomarker in NSCLC [0.03%]
集成机器学习和因果推理揭示CHRDL1作为NSCLC诊断和功能生物标志物
Chao Shen,Jin Wang,Yufeng Tu et al.
Chao Shen et al.
Background: Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer-related deaths, largely due to late diagnosis and limited early biomarkers. Integrating machine learning (ML) with causal inference m...
Bibliometric analysis reveals the current status and future trends of cancer associated fibroblasts research in breast cancer [0.03%]
基于文献计量的分析揭示乳腺癌相关成纤维细胞研究现状及未来趋势
Shixue Jing,Siping Zhou,Cui Jia et al.
Shixue Jing et al.
Background: Breast cancer is one of the most common and lethal heterogeneous cancers among women worldwide, posing a significant threat to female health. Cancer associated fibroblasts (CAFs) play a critical role in the in...
A systems biology approach to identify key targets in KRAS/BRAF-mutated colorectal cancer [0.03%]
采用系统生物学方法识别KRAS/BRAF突变型结直肠癌的关键靶点
Shiva Shiravi,Negar Mottaghi-Dastjerdi,Behzad Shahbazi et al.
Shiva Shiravi et al.
Background: KRAS and BRAF mutations are critical oncogenic drivers in colorectal cancer (CRC), with distinct molecular and clinical implications. Methods:...
Integrative eQTL and Mendelian randomization analysis reveals key genes in colorectal cancer [0.03%]
整合型eQTL和孟德尔随机化分析揭示结直肠癌关键基因
Jun Zhou,Haihong Lin,Ju Zheng et al.
Jun Zhou et al.
Background: Colorectal cancer (CRC) represents a crucial global public health concern, yet its molecular mechanisms underlying CRC are not completely comprehended. This study utilizes Mendelian randomization (MR) in conju...
Utilizing a novel mitochondrial-related gene signature for predicting the prognosis and immunological impact in bladder cancer [0.03%]
利用一种新颖的线粒体相关基因特征谱预测膀胱癌预后及免疫学影响
Gongping Wu,Chengwei Fan,Xueming Ma et al.
Gongping Wu et al.
Background: Mounting evidence highlights the critical role of mitochondrial dysfunction, driven by mitochondrial-related genes (MTRGs), in the development, progression, and therapeutic response of cancer. However, a compr...
Single cell transcriptomic analysis reveals molecular mechanisms of chemoresistance and immune microenvironment remodeling in ovarian cancer [0.03%]
单细胞转录组分析揭示卵巢癌化疗耐药及免疫微环境重塑的分子机制
Xia Hu,Caifang Du,Dongjie Du et al.
Xia Hu et al.
Background: Chemotherapy resistance remains a major clinical challenge in ovarian cancer treatment, limiting therapeutic efficacy and patient survival. Understanding the molecular mechanisms underlying chemoresistance at ...
Adenylosuccinate lyase (ADSL) is a pan-cancer prognostic and immune biomarker with distinct roles in hepatocellular carcinoma [0.03%]
腺苷琥珀酸裂解酶（ADSL）是一种泛癌症预后和免疫生物标志物，在肝细胞癌中具有不同的作用
Weixiong Zhu,Xuefan Zeng,Jianqi Qin et al.
Weixiong Zhu et al.
Background: The role of ADSL in various types of cancer remains inadequately understood. We encompassed a comprehensive examination of the mechanistic features of ADSL and explored its viability as a broad-spectrum predic...
A pan-cancer analysis of the oncogenic role of KDELR2 in human cancers [0.03%]
泛癌症分析人类癌症中KDELR2的致癌作用
Yu Xie,Dong Chen,Qi Zhang
Yu Xie
Background: KDELR2, a retrograde transport receptor involved in ER protein homeostasis, has emerged as a potential contributor to cancer development. However, its comprehensive expression profile and immunological roles a...