DNA methylation-mediated ADA overexpression drives pancreatic cancer progression [0.03%]
DNA甲基化介导的ADA过表达驱动胰腺癌进展
Jingyi Zeng,Juying Jiao,Bo Lin et al.
Jingyi Zeng et al.
Background: Pancreatic cancer (PC) is characterized by its aggressive nature, limited options for radiochemotherapy, and poor prognosis, highlighting the urgent need for the identification of novel therapeutic targets to ...
Feasibility of different meningioma delineation approaches on [18F]SiTATE PET/CT imaging [0.03%]
不同方法定义的脑膜瘤在[18F]SiTATE PET/CT显像中的可行性研究
Sophie Carina Kunte,Lena M Unterrainer,Simon Lindner et al.
Sophie Carina Kunte et al.
The impact of immune cells on the risk of breast cancer: a Mendelian randomization study [0.03%]
免疫细胞对乳腺癌风险的影响：孟德尔随机化研究
Nana Zhang,Hao Wang,Zhenfeng Huang et al.
Nana Zhang et al.
Background: The immune system is closely linked to the prognosis of breast cancer (BC). However, it remains unclear whether changes in immune cells contribute to the etiology of BC. ...
Mendelian randomization analysis unveils causal associations between immune cells, metabolites, and lung cancer risk [0.03%]
孟德尔随机化分析揭示了免疫细胞、代谢物和肺癌风险之间的因果关系
Yanqing Mao,Ting Fu,Yanan Wang et al.
Yanqing Mao et al.
Background: Lung cancer is the leading cause of cancer-related deaths worldwide, with the highest incidence rates in the United States, posing significant public health challenges. Although treatment modalities have advan...
Clinical value and mechanism of CDKN2A in clear cell renal cell carcinoma [0.03%]
CDKN2A在透明细胞肾癌的临床价值及机制研究
Yan Li,Songsong Wang,Yilong Lin et al.
Yan Li et al.
Background: Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer, with its incidence increasing annually. This study aims to investigate the role of the Cyclin-Dependent Kinase Inhibitor 2 A (C...
LINC01063 promotes colon cancer progression via the miR-134-5p/KRAS axis and serves as a prognostic biomarker [0.03%]
长链非编码RNA LINC01063通过miR-134-5p/KRAS轴促进结肠癌进展并作为预后生物标志物 служит
Qianli Liu,Sijia Sun,Rui Fan
Qianli Liu
Background: Despite advances in treatment, the prognosis of colon cancer is still unsatisfactory, and there is an urgent need for reliable biomarkers and mechanistic studies. The role of long non-coding RNAs (lncRNAs) in ...
DOCK2 modulates immune checkpoint inhibitor responsiveness and prognosis in cutaneous melanoma through multi-omics and single-cell T cell dynamics profiling [0.03%]
DOCK2通过多组学和单细胞T细胞动力学谱分析调节免疫检查点抑制剂在皮肤黑色素瘤中的反应性和预后
Huicong Wang,Chao Feng,Chengjun Lao et al.
Huicong Wang et al.
Background: Skin cutaneous melanoma (SKCM) is a highly aggressive malignancy that arises from melanocytes and has been associated with a notable increase in incidence and mortality rates across the globe. The current trea...
Nomogram for predicting postoperative recurrence in elderly patients with hepatocellular carcinoma based on multimodal ultrasound [0.03%]
基于多模态超声的老年人肝细胞癌术后复发预测列线图
Yinling Jiang,Lina Zhao
Yinling Jiang
Objective: To develop and validate a nomogram prediction model for postoperative recurrence in elderly patients with hepatocellular carcinoma (HCC) based on multimodal ultrasound parameters. ...
Roles, mechanisms, and clinical implications of circHIPK3 in female malignancy: a comprehensive review [0.03%]
circHIPK3在女性恶性肿瘤中的作用、机制及临床意义：综合述评
Yue-Feng Liu,Ni Jiang,Yan-Jiao Huang et al.
Yue-Feng Liu et al.
Luteolin regulates pyroptosis of triple-negative breast cancer cells through AKT signaling [0.03%]
黄酮类化合物山柰酚通过AKT信号调节三阴性乳腺癌细胞的焦亡作用研究
Gu Junwei,Lan Tian,Hu Zujian et al.
Gu Junwei et al.
Triple-negative breast cancer (TNBC), the most aggressive molecular subtype of breast cancer, currently lacks effective therapeutic targets. While radiotherapy and chemotherapy remain the mainstay of treatment, therapy resistance frequently...