Proteomic analysis of Burkitt lymphoma tissues: insights into the impact of age and EBV infection on protein expression and molecular characteristics [0.03%]
Burkitt淋巴瘤组织的蛋白质组分析：年龄和EB病毒对蛋白表达及分子特征影响的新认识
Yu Huang,Shuang Zheng,Xinyi Huang et al.
Yu Huang et al.
We aim to investigate the molecular heterogeneity of Burkitt lymphoma (BL) by analyzing the impact of age and Epstein-Barr virus (EBV) infection on protein expression in tumor tissues. Using liquid chromatography-mass spectrometry (LC-MS), ...
Global trends in prostate cancer burden among adults aged 80 years and older from 1990 to 2021 based on the global burden of disease 2021 [0.03%]
基于全球疾病负担研究（2021年）的1990年至2021年老年男性前列腺癌疾病负担的全球趋势（80岁及以上）
Xin Zhu,Yazhe Zhou,Xin Yang et al.
Xin Zhu et al.
Objectives: This study aimed to investigate the global, regional, and national burden of prostate cancer (PCa) among adults aged 80 years and older (≥ 80 years) from 1990 to 2021. ...
Epigenetic reprogramming as the nexus of cancer stemness and therapy resistance: implications for biomarker discovery [0.03%]
表观遗传重编程连接癌症干细胞属性与治疗抵抗的机制在生物标志物发现中的应用
Chu Xin Ng,Shin Yuh Lee,Xin Yi Yap et al.
Chu Xin Ng et al.
Therapeutic failure in cancer often arises from the ability of tumor cells to adapt to external stressors such as drug exposure, metabolic and oxidative stress, and immune surveillance within the tumor microenvironment (TME). This adaptive ...
Ubiquitin-specific proteases as key regulators in the malignant progression and therapy resistance of colorectal cancer: current insights and future perspectives [0.03%]
泛素特异性蛋白酶在结直肠癌恶性进展和治疗抵抗中的关键调节作用：当前见解与未来展望
Junyan Li,Shifan Deng,Wei Yu et al.
Junyan Li et al.
As a member of the DUBs (deubiquitinating enzymes) family, USPs (ubiquitin-specific peptidases) play a crucial regulatory role in the occurrence and progression of various malignancies. This review summarizes the current research on USPs in...
Development and validation of a deep learning model for individualized survival prediction in advanced cervical cancer [0.03%]
用于预测晚期宫颈癌患者个体化生存率的深度学习模型的开发和验证
Wanying Sun,Qingqing Liu,Yiping Hao et al.
Wanying Sun et al.
Background: Clinical staging remains the most commonly used systems for advanced cervical cancer in clinical practice and cannot provide satisfactory prognostication. Deep learning model could capture complex and nonlinea...
Bibliometric analysis of global research on breast cancer with HER2-low expression [0.03%]
全球HER2低表达型乳腺癌研究的 bibliometriks 分析
Junpeng Zhu,Jin Hu,Hao Lei et al.
Junpeng Zhu et al.
Background: The abnormal expression of Human Epidermal Growth Factor Receptor 2 (HER2) is closely related to the prognosis of breast cancer. Since the concept of HER2-low expression was introduced in 2018, researches on H...
VDAC1 as prognostic marker and therapeutic target in lung adenocarcinoma: a study integrating bioinformatics and experimental validation [0.03%]
肺癌腺癌的预后标志物和治疗靶点VDAC1：基于生物信息学整合实验验证的研究
Lei Cheng,Deping Zhao
Lei Cheng
Background: Research on the expression and molecular mechanisms of voltage-dependent anion channels (VDACs) in lung adenocarcinoma (LUAD) remains limited. ...
NAP1L4 in hepatocellular carcinoma progression and treatment from gene expression to clinical impact [0.03%]
从基因表达到临床影响的肝细胞癌进展和治疗中的NAP1L4作用机制研究
Junjie Lin,Hehe Yin,Zihan Xie et al.
Junjie Lin et al.
Background: Hepatocellular carcinoma (HCC) remains one of the deadliest malignancies globally, posing substantial health threats and economic burdens. Despite advances in therapeutic modalities-including surgical resectio...
Metastatic patterns and survival outcomes across molecular subtypes in a large cohort of breast cancer patients from the Shiraz breast cancer registry [0.03%]
基于设拉子乳腺癌登记数据库的大规模人群的不同分子亚型的转移模式和生存预后分析研究
Majid Akrami,Raha Shahrokhi,Sina Masoumi et al.
Majid Akrami et al.
Purpose: Breast cancer molecular subtypes significantly influence metastatic behavior and survival outcomes. However, data on subtype-specific patterns of distant metastasis and prognosis in Middle Eastern populations rem...