Predictive value of DWI signal and IVIM of pelvic bone marrow for hematological toxicity in rectal cancer patients undergoing concurrent chemoradiotherapy [0.03%]
弥散加权成像信号及胰岛素样生长因子-1 mRNA表达对直肠癌患者同期放化疗骨髓毒副作用的预测价值研究
Liang Hu,Jiang-Feng Pan,Zheng Han et al.
Liang Hu et al.
Integrated transcriptomic and single-cell analysis reveals cell cycle dysregulation and cellular heterogeneity in lung cancer [0.03%]
整合转录组和单细胞分析揭示肺癌中的细胞周期失调和细胞异质性
Yuzi Zhang,Wencheng Che,Qingchuan Li et al.
Yuzi Zhang et al.
Background: Lung cancer remains one of the leading causes of cancer-related mortality worldwide, with complex molecular mechanisms underlying its pathogenesis. Understanding the transcriptional landscape and cellular hete...
Integrating multi-omics data and machine learning to identify endocrine disrupting chemicals targeting key ccRCC-related genes [0.03%]
整合多组学数据和机器学习以识别靶向关键ccRCC相关基因的内分泌干扰物
Mengzhuo Zheng,Debiao Wang,Bo Guan et al.
Mengzhuo Zheng et al.
Clear cell renal cell carcinoma (ccRCC) is a highly aggressive and metastatic malignancy that poses a serious threat to patient health. While its development involves both genetic and environmental influences, the interactions between genet...
VAMP5 promotes glioma progression through bioinformatics analysis clinical correlation and functional validation [0.03%]
生物信息学分析、临床相关性及功能验证VAMP5通过生物信息学分析、临床相关性及功能验证促进胶质瘤进展
Yujie Ji,Xiangyu Dai,Haixin Zeng et al.
Yujie Ji et al.
Background: Glioma is the most common and aggressive primary brain tumor, characterized by high heterogeneity, invasive growth, and poor prognosis. Identifying novel molecular drivers is essential for improving diagnosis,...
CCDC86 modulates immune cell infiltration and disease progression in head and neck squamous cell carcinoma [0.03%]
CCDC86在头颈鳞癌浸润免疫细胞和疾病进展中的作用研究
Fei He,Yang Liu,Xinjian Zhang et al.
Fei He et al.
Background: Head and neck squamous cell carcinoma (HNSCC) is a prevalent and aggressive cancer with poor prognosis despite advancements in treatment. The immune system plays a crucial role in HNSCC progression, yet the sp...
Mitochondrial-associated PCD signature defines immune landscape, therapeutic sensitivity, and prognosis in hepatocellular carcinoma [0.03%]
线粒体相关PCD标志物定义了肝细胞癌的免疫特征、治疗敏感性及预后情况
Xiao-Qin Luo,Yi-Min Cao,Yang Peng et al.
Xiao-Qin Luo et al.
Mitochondrial-associated programmed cell death signatures (MPCDS) have emerged as critical indicators of cancer progression and treatment response. In hepatocellular carcinoma (HCC), mitochondrial dysfunction and dysregulated PCD pathways a...
Identifying and validating SMARCAL1 as a prognostic and immunotherapy predictive biomarker for NSCLC [0.03%]
识别并验证SMARCAL1作为NSCLC预后和免疫治疗预测生物标志物的能力
Zeyan Pan,Zhenli Hu,Yunshuo Zhang et al.
Zeyan Pan et al.
Recent studies have highlighted the critical role of SMARCAL1 in cancer immune evasion, suggesting its potential as a target for immunotherapy. However, its prognostic and predictive value across diverse cancers remains unclear. In this stu...
Graph neural network-based multi-label classification of breast cancer using multiparametric MRI and clinical features [0.03%]
基于图形神经网络的乳腺癌多标签分类：使用多参数MRI和临床特征
Shahed Salehzehi,Shabnam Jafarpoor Nesheli,Alireza Eftekhar et al.
Shahed Salehzehi et al.
Bioinformatics-based screening and prediction of compounds and antigen epitopes for immune targets with point mutations in colitis-associated colorectal cancer [0.03%]
基于生物信息学的炎症相关结直肠癌点突变免疫靶标化合物及抗原表位筛选与预测
Xinyi Peng,Quan Sun,Dongli Zhao et al.
Xinyi Peng et al.
Objective: This study aimed to identify and predict bioactive small molecules and immunogenic antigen epitopes targeting proteins with point mutations in colitis-associated colorectal cancer (CAC), using integrative bioin...
A rare case of multiple malignant tumors combined with central adrenal insufficiency: a case report [0.03%]
中枢性肾上腺皮质功能减退伴发多种恶性肿瘤一例报告
Pinpin Kong,Pengshuai Liu,Xiaofeng Liu et al.
Pinpin Kong et al.