Stratifin as a biomarker for predicting progression and prognosis in endometrial cancer [0.03%]
stratifen作为内膜癌进展和预后的生物标志物
Jing Zhu,Xiao-Xin Ma
Jing Zhu
Cellular senescence related gene signature predicts prognosis and immune features in skin cutaneous melanoma [0.03%]
细胞衰老相关基因特征预测皮肤黑色素瘤的预后和免疫特征
Mengna Li,Xintao Cen,Yan Yan et al.
Mengna Li et al.
Background: Skin cutaneous melanoma (SKCM) is the deadliest skin cancer, with rising global incidence. Cellular senescence plays an essential role in tumorigenesis, progression, and immune modulation in cancer, however, i...
A prognostic model derived from PANoptosis-associated subtypes unveils immunological features and therapeutic vulnerabilities in cervical cancer [0.03%]
基于PANoptosis相关亚型衍生的预后模型揭示宫颈癌免疫特征和治疗弱点
Yuehong Tong,Wei Deng,Lili Xu et al.
Yuehong Tong et al.
Background: Cervical cancer progression is intricately linked to dysregulated cell death pathways, particularly PANoptosis, a coordinated form of programmed cell death. However, prognostic biomarkers and immunological imp...
Integrated mendelian randomization and bioinformatics approach unveiling the immunological and prognostic significance of FBXO2 in breast cancer [0.03%]
整合孟德尔随机化和生物信息学方法揭示FBXO2在乳腺癌中的免疫学和预后意义
Rongzhi Huang,Zhibai Chen,Min Mao et al.
Rongzhi Huang et al.
Background: Breast cancer (BRCA) is a typical females' malignant tumors. Ubiquitin-proteasome system (UPS) is a critical pathway for pathogenesis of BRCA. Activation of UPS is determined by SKP1-cullin 1-F-box protein (SC...
Sex hormone receptor signaling networks drive pancreatic solid-pseudopapillary neoplasm pathogenesis and therapy [0.03%]
性激素受体信号网络驱动胰腺实性假乳头状瘤的发生和发展及治疗响应
Yayu Huang,Tianlin He
Yayu Huang
Solid-pseudopapillary neoplasm of the pancreas (SPN) represents a rare pancreatic tumor with a low malignant potential, predominantly affecting young women. This suggests a potential involvement of sex hormones in the development of the tum...
Expression and prognostic diagnostic significance of RGS gene family in breast cancer [0.03%]
乳腺癌中RGS基因家族的表达及预后诊断意义
Huanhuan Wang,Ming Feng,Hong Huang et al.
Huanhuan Wang et al.
Global trends and future directions in COVID-19 and leukemia research from 2020 to 2024 [0.03%]
2020至2024年全球COVID-19与白血病研究热点及展望
Zelin Yang,Hui Zhao,Jie Tian
Zelin Yang
Background: The COVID-19 has disproportionately affected leukemia patients, with outcomes significantly worse than those in the general population due to their immunocompromised status. Despite substantial growth in COVID...
Prognostic factors and the role of chemotherapy in patients with pT3N0M0 gastric cancer: a propensity score matching analysis based on the SEER database [0.03%]
基于SEER数据库的pT3N0M0胃癌患者预后因素及化疗作用的倾向性匹配分析
Tao Hu,Xinhao Chen,Wangwang Chen
Tao Hu
Background: The benefit of chemotherapy for pT3N0M0 gastric cancer after curative gastrectomy remains controversial. This study aimed to identify prognostic factors and evaluate the influence of chemotherapy on pT3N0M0 GC...
Inhibition of FXa could be a novel therapeutic target associated with hypoxia-associated tumor behavior? [0.03%]
FXa的抑制可能是与低氧相关肿瘤行为相关的新的治疗靶点？
Ozge Bayrak,Nazlı Mert,Yasemin Basbinar et al.
Ozge Bayrak et al.
Background: Factor Xa (FXa) plays a role in promoting cancer growth and metastasis via protease-activated receptors. The main aim of this study was to investigate the effect of FXa inhibition, which is known to play a cru...
Qiang Zhao,Kunpeng Du
Qiang Zhao
Background: Gliomas pose a significant challenge in the realm of neuro-oncology, marked by high rates of morbidity and mortality, as well as substantial healthcare costs. Current treatment strategies include surgical proc...