Collagen dynamics in the breast cancer tumor microenvironment and therapeutic perspectives [0.03%]
乳腺癌肿瘤微环境中的胶原蛋白动力学及其治疗前景
Danping Wu,Lu Liu,Ying Jiang et al.
Danping Wu et al.
Breast Cancer (BC) remains one of the most prevalent malignancies among women globally, with its pathogenesis and clinical progression being profoundly regulated by the tumor microenvironment (TME). Collagen, the most abundant extracellular...
Prognostic impact of primary tumor resection and nomogram development for survival prediction in colonic neuroendocrine carcinoma patients with liver metastasis: a SEER database-based study [0.03%]
结肠神经内分泌癌肝转移患者初次肿瘤切除的预后影响及生存预测列线图模型的建立：基于SEER数据库的研究
Jingxiong Chen,Haizhou Diao,Kai Qian et al.
Jingxiong Chen et al.
Objective: This study aimed to investigate the prognostic impact of primary tumor resection in colonic neuroendocrine carcinoma (NECs) patients with liver metastasis, compare survival outcomes between left- and right-side...
Crossroads of cell fate: miR-34-mediated regulation of apoptosis and autophagy in glioblastoma [0.03%]
细胞命运的十字路口：miR-34介导的胶质母细胞瘤凋亡和自噬调节
Tareq Nayef AlRamadneh,Waleed K Abdulsahib,Sajida Hussein Ismael et al.
Tareq Nayef AlRamadneh et al.
Glioblastoma (GBM) is the most aggressive and treatment-resistant form of primary brain tumor, characterized by rapid proliferation, extensive heterogeneity, and evasion of programmed cell death. Among emerging molecular regulators, microRN...
Hengwei Du,Guoxing Yu,Ruiqi Hu et al.
Hengwei Du et al.
Ovarian cancer (OC), as one of the three major gynecological tumors, has been known as the "silent killer". It is characterized by high mortality, high recurrence rate, and frequent drug resistance. Chronic stress has been increasingly reco...
Apigenin combined with cisplatin suppressed the progression of colorectal cancer by targeting the KRT23/Wnt/β-catenin signaling pathway [0.03%]
染料木素联合顺铂通过靶向角蛋白23/Wnt/β-连环蛋白信号通路抑制结直肠癌进展
Lei Dong,Feng Yang,Xue Wang et al.
Lei Dong et al.
Colorectal cancer (CRC) represented a pervasive manifestation of malignant neoplasia within the digestive tract. Apigenin, exhibiting a multitude of physiological attributes and pharmacological actions, has undergone extensive scrutiny for ...
Causal associations between circulating metabolites and risk of neuroblastoma: a bidirectional Mendelian randomization study [0.03%]
循环代谢产物与神经母细胞瘤风险的因果关联：双向孟德尔随机化研究
Han Wu,Zhe Zhao,Changlin Chen et al.
Han Wu et al.
Background: The current understanding of the relationship between circulating metabolites and neuroblastoma (NB) risk is insufficient. Herein, bidirectional Mendelian randomization (MR) studies were utilized to examine th...
Systematic pan-cancer analysis of IL3RA carcinogenesis in human tumors, combined with bioinformatics analysis [0.03%]
人肿瘤中白细胞介素3受体α(IL3RA)致癌作用的泛癌分析及生物信息学分析
Rongyang Zou,Qiong Wu,Fang Fang et al.
Rongyang Zou et al.
Previous studies have demonstrated the significance of IL3R in hematological malignancies. Our research has further revealed the impact of IL3RA on the biological behavior of breast cancer cells. However, there is a need for a comprehensive...
Integrated analysis of the oncogenic value of CPNE3 in non-small cell lung cancer [0.03%]
CPNE3在非小细胞肺癌中的致癌价值的综合分析
Pei Pang,Lanxin Tian,Jianjie Zhu et al.
Pei Pang et al.
Background: Vasculogenic mimicry (VM) is correlated with higher tumor grade, cancer cell metastasis and invasion, and poorer prognosis in lung cancer patients. CPNE3 reportedly acts as an oncogene to promote tumorigenesis...
A comprehensive review redefining viruses as therapeutic agents in cancer treatment [0.03%]
病毒作为癌症治疗的疗法剂的全面回顾及重新定义
Anjana Jadhav,Aravind J,Trupti Patel
Anjana Jadhav
Oncolytic viruses (OVs) possess the distinctive capability to selectively eliminate malignant cells while exerting reduced impact on healthy tissues compared to traditional therapies. This unique attribute renders them valuable candidates f...
PTBP1 functions as a suppressor of ferroptosis in endometrial carcinoma cells by stabilizing SLC7A11 mRNA [0.03%]
PTBP1通过稳定SLC7A11 mRNA在子宫内膜癌细胞中发挥铁死亡抑制作用
Keke Zhu,Ke Zhang,Hui Li et al.
Keke Zhu et al.
The RNA-binding protein polypyrimidine tract-binding protein 1 (PTBP1) facilitates tumor progression in various cancers by interacting with mRNAs of key oncogenes and tumor suppressors, thereby regulating their mRNA stability, alternative s...