The role of cranial radiotherapy in managing neurological symptoms of brain metastases from pulmonary choriocarcinoma: a case report and literature review [0.03%]
颅脑放射治疗在肺绒癌脑转移瘤症状管理中的作用：1例报告和文献复习
Haozheng Lu,Aimin Jiang,Xijun Liu et al.
Haozheng Lu et al.
Background: Primary pulmonary choriocarcinoma (PPC) is a rare and highly malignant germ cell tumor. This tumor is prone to brain metastasis, severely affecting the quality of life of patients. The optimal treatment regime...
Bannayan-Riley-Ruvalcaba syndrome, etiology, clinical manifestations, diagnostic approaches, and current therapeutic measures: a narrative review [0.03%]
班奈安-赖利-鲁瓦尔卡巴综合征的病因、临床表现、诊断方法及目前治疗方法：综述性文章
Ahmed Mohammed Alolyan,Najla Ibrahim Alenezi,Layla Nasser Alqahtani et al.
Ahmed Mohammed Alolyan et al.
Bannayan-Riley-Ruvalcaba Syndrome (BRRS) is a rare genetic disorder caused by germline mutations in the phosphatase and tensin homolog (PTEN) gene, leading to overgrowth and classified under PTEN hamartoma tumor syndrome (PHTS). It manifest...
Multi-omics highlights the impacts of cryptorchidism history on immune microenvironment variation in TGCT [0.03%]
多组学揭示隐睾症对睾丸癌免疫微环境变异影响的作用
Gao Li,Yaqian Zhao,Mengtong Wang et al.
Gao Li et al.
Background: The unique altered biological processes in testicular germ cell tumor (TGCT) patients with cryptorchidism history require further investigation and the accumulation of tumor-related features in cryptorchidism ...
Combination of cellular retinoic acid-binding protein 2 overexpression and all-trans retinoic acid synergistically inhibits oesophageal squamous cell carcinoma progression [0.03%]
细胞视黄酸结合蛋白2高表达与全反式维甲酸协同抑制食管鳞癌进展
Mengyan Li,Litao Dai,Yuqing Ma
Mengyan Li
Objective: All-trans retinoic acid (ATRA) has demonstrated great potential in cancer treatment; however, the molecular mechanism for the anti-tumour effects of Cellular retinoic acid-binding protein 2 (CRABP2) and ATRA in...
Mendelian randomization analysis of lipidomic profiles and thyroid cancer risk in European populations [0.03%]
欧洲人群脂质组谱系与甲状腺癌风险的孟德尔随机化分析
Siyan Li,Hao Yu,Dianlong Zhang et al.
Siyan Li et al.
Thyroid cancer (TC) remains a prevalent malignancy with a rising incidence worldwide, yet the causal relationship between the plasma lipidome and TC is still poorly understood. This study aims to explore this relationship using two-sample M...
Deciphering the oncogenic role of key genes in HNSC: insights from multi-omics and functional studies [0.03%]
头颈部鳞状细胞癌中关键基因致癌作用的解析：多组学和功能研究的新见解
Suad A Alghamdi,Mohammed Alissa
Suad A Alghamdi
Background: Recent evidence highlighted head and neck squamous cell carcinoma (HNSC) as a significant health concern, demanding precise clinical management. This study aimed to identify molecular biomarkers, delineate the...
Mendelian randomization analysis integrating GWAS and eQTL data identified potential regulatory genes associated with prostate cancer in neural cells [0.03%]
整合GWAS和eQTL数据的孟德尔随机化分析鉴定出与神经细胞中前列腺癌相关的潜在调控基因
Jiahao Guo,Hao Xie,Quanting Yin et al.
Jiahao Guo et al.
Effects of beta-cyclodextrin-Combretastatin A-4 nanoparticles containing selenium on apoptosis and metastasis of U-87MG glioblastoma cancer cells [0.03%]
β-环糊精-含硒的Combretastatin A-4纳米颗粒对U-87MG胶质母细胞瘤癌细胞凋亡和转移的影响
Seyedeh Motahareh Hosseini,Fatemehsadat Hosseini,Elaheh Gheybi et al.
Seyedeh Motahareh Hosseini et al.
Background: Glioblastoma (GBM), the most aggressive primary brain tumor, faces significant treatment challenges due to drug resistance, blood-brain barrier limitations, and severe side effects of conventional therapies. T...
Multiomic analysis of CCNE1 amplification associated molecular and immune features in gynecological cancers [0.03%]
CCNE1扩增相关分子和免疫特征的多组学分析在妇科肿瘤中的应用
Linlin Liu,Wenjin Zheng,Liang Wen et al.
Linlin Liu et al.
Progress in research on the mechanisms and therapeutic strategies of SLC7A11 regulation in glioma [0.03%]
胶质瘤中SLC7A11调控的机制和治疗策略研究进展
Qianfeng Wei,Bangfa Xiong,Guangming Yang et al.
Qianfeng Wei et al.