Lidocaine suppresses HER2-positive breast cancer cell proliferation by targeting the OGT-CCNL1 axis [0.03%]
利多卡因通过针对OGT-CCNL1轴抑制HER2阳性乳腺癌细胞增殖
Yunfei Sun,Bo Liu,Xuan Zhang et al.
Yunfei Sun et al.
Background: HER2-positive breast cancer, known for its heterogeneity and complex molecular mechanisms, poses a significant therapeutic challenge. Lidocaine, a widely used local anesthetic, has recently been identified as ...
Advancing breast cancer treatment through dual targeting CAR T cell therapy [0.03%]
通过双重靶向CAR-T细胞治疗推进乳腺癌治疗
Mujibullah Sheikh,Dilip Madia,Umesh B Telrandhe et al.
Mujibullah Sheikh et al.
Development and validation of a novel disulfidptosis-related gene signature for prediction of survival and immune microenvironment in osteosarcoma by WGCNA analysis [0.03%]
基于WGCNA分析的骨肉瘤预后型二硫化物酶解相关基因特征的发展与验证
Yibin Zheng,Hang Cai,Hongbin Huang et al.
Yibin Zheng et al.
Disulfidptosis was reported to be associated with the malignant progression of various tumors. This study was aimed to investigate the prognostic significance of disulfidptosis-related genes (DRGs) in osteosarcoma (OS). Ten previously repor...
Incidence, severity, and risk factors of early postoperative complications in laryngectomy patients: a retrospective analysis [0.03%]
喉切除术患者早期术后并发症的发生率、严重程度及危险因素：回顾性分析
Meiqin Shi,Ping Song,Kun Du et al.
Meiqin Shi et al.
Purpose: To determine the incidence, severity and risk factors of complications in patients undergoing laryngectomy. Methods: 433 patie...
Development and validation of a machine learning-based pathomics nomogram for prognostic prediction in endometrial cancer [0.03%]
基于机器学习的病理组学模型在子宫内膜癌预后预测中的建立和验证
Xianhua Han,Junyu Qiu
Xianhua Han
Introduction: Endometrial cancer (EC) is a common gynecologic malignancy with increasing incidence and notable molecular heterogeneity. This study aimed to develop a non-invasive, cost-effective prognostic model using pat...
Therapeutic effects and mechanisms of action of Baicalein on stomach cancer: a comprehensive systematic literature review [0.03%]
黄芩素治疗胃癌的疗效及其作用机制的系统文献综述
Mingpeng Cao,Ying Tang,Razzagh Abedi-Firouzjah et al.
Mingpeng Cao et al.
Background: Stomach cancer, or gastric cancer (GC), is a major global health problem characterized by the malignant proliferation of cells in the gastrointestinal lining. Recent studies have highlighted the potential ther...
Immunotherapy for pleural mesothelioma: from innovation to the frontlines of core clinical questions [0.03%]
免疫治疗在胸膜间皮瘤中的应用：从创新到核心临床问题的前沿阵地
Tatsuya Yoshida,Kozo Kuribayashi
Tatsuya Yoshida
In August 2018, Japan's Pharmaceuticals and Medical Devices Agency (PMDA) became the first in the world to approve immune checkpoint inhibitor (ICI) monotherapy with nivolumab for previously treated, unresectable, advanced, or recurrent ple...
Publisher Correction: Expressions, immune associations, and prognostic values of mitochondrial ribosomal protein MRPL3 in the Pan cancer landscape [0.03%]
出版更正：线粒体核糖体蛋白MRPL3在泛癌中的表达、免疫关联及预后价值
Jing Lin,Wenzhe Chen,Yaodong Zhao et al.
Jing Lin et al.
Published Erratum
Discover oncology. 2025 Dec 4;16(1):2194. DOI:10.1007/s12672-025-04204-5 2025
Surgical intervention strategies for tumor microenvironment (TME) associated therapeutic resistance [0.03%]
与肿瘤微环境(TME)相关治疗耐药性的外科干预策略
Dong Chen,Hanyu Wang,Xu Che
Dong Chen
The functions of circular RNAs and long noncoding RNAs in cholangiocarcinoma [0.03%]
circRNA和长非编码RNA在胆管癌中的功能研究进展
Zhangdi Yan,Lixin Du,Xiaotong Zhang et al.
Zhangdi Yan et al.
Cholangiocarcinoma (CCA) is a highly aggressive malignancy with an extremely poor prognosis. The rising incidence of cholangiocarcinoma in recent years underscores the need for new diagnostic biomarkers and therapeutic targets. Circular RNA...