Integrative machine learning identifies lactylation-related gene signature prognostic for chemotherapeutic efficacy in colorectal carcinoma [0.03%]
集成机器学习识别出与化疗疗效相关的乳酰化相关基因特征(signature)用于结直肠癌预后判断
Hui Hu,Fang Peng,QinWen Ba et al.
Hui Hu et al.
Background: Lactylation, a recently discovered post-translational modification, has emerged as a critical regulator in cancer biology. Although chemotherapy remains the first-line treatment for metastatic colorectal cance...
Exploring the therapeutic potential of human umbilical cord mesenchymal stem cells derived extracellular vesicles in cancer immunotherapy [0.03%]
探究人脐带间充质干细胞来源的外泌体在肿瘤免疫治疗中的治疗潜力
Faeze Dehghani,Mona Daghaighei,Alireza Azani et al.
Faeze Dehghani et al.
The therapeutic potential of human umbilical cord mesenchymal stem cells derived extracellular vesicles (hUCMSC-EVs) in cancer immunotherapy is an emerging area of research that offers promising avenues for enhancing treatment efficacy. Thi...
Blood ctDNA-specific markers predict the risk of peritoneal metastasis for advanced gastric cancer [0.03%]
血液ctdna特异性标志物预测晚期胃癌患者腹膜转移风险
FangZhou Xing,JunYing Shi,Ying Mu et al.
FangZhou Xing et al.
Objective: The aim of this study was to investigate the value of early postoperative ctDNA dynamic monitoring (TP53/KRAS/PIK3CA gene mutations) combined with clinicopathologic factors in risk stratification of postoperati...
Clinical characteristics, treatment status and prognosis analysis of elderly patients with ovarian cancer: a real world clinical study [0.03%]
老年卵巢癌患者临床特征、治疗状况和预后分析：一项真实世界研究
Xiaowei Wang,Liang Xi,Yahui Shen et al.
Xiaowei Wang et al.
Objective: To investigate the clinical features, treatment status and identify the prognostic factors of elderly patients with ovarian cancer. Methods: ...
Bibliometric analysis and recent trends on tyrosine kinase inhibitors in leukemia [0.03%]
酪氨酸激酶抑制剂在白血病研究中的 bibliometric 分析及最新趋势
Jiao Cheng,Yuan Fang,Juancong Dong et al.
Jiao Cheng et al.
Background: Leukemia treatment has been revolutionized by tyrosine kinase inhibitors (TKIs), but comprehensive understanding of the global research landscape remains fragmented. This study aims to provide a systematic bib...
Identification of MFSD3 as a potential prognostic biomarker of cervical cancer [0.03%]
MFSD3作为宫颈癌预后生物标志物的鉴定研究
Lixiang Guo,Qiang Zhang
Lixiang Guo
Background: Cervical cancer (CC) is a common malignant tumor of the female reproductive system. Currently, patients with advanced or recurrent CC have poor prognosis. The aim of this investigation is to pinpoint key genes...
Research progress on carcinogenic factors and personalized treatment of oral cancer [0.03%]
口腔癌致癌因素及个性化治疗研究进展
Kebin Xu,Qiaozhi Yang,Weiyun Chen et al.
Kebin Xu et al.
The oncogenic role of lncRNA DSG2-AS1 and its functional link to SGK1 in laryngeal squamous cell carcinoma [0.03%]
长链非编码RNA DSG2-AS1在喉鳞状细胞癌中的致癌作用及其与SGK1的功能联系
Najmeh Parvaz,Payam Mohammadi,Maryam Lotfi et al.
Najmeh Parvaz et al.
Identification of oxidative stress-related genes in papillary thyroid carcinoma and their common targets with resveratrol based on bioinformatics, network pharmacology, and molecular docking [0.03%]
基于生物信息学、网络药理学和分子对接的氧化应激相关基因在乳头状甲状腺癌中的识别及其与白藜芦醇的共同靶点
Dongliang Shi,Liang Chen,Chenhao Li et al.
Dongliang Shi et al.
Objective: This study aims to identify oxidative stress-related genes (OSGs) in papillary thyroid carcinoma (PTC) and their common targets with resveratrol. ...
Causal relationships between cerebrospinal fluid metabolites, immune cell traits, and head and neck cancers [0.03%]
脑脊液代谢物、免疫细胞特性与头颈癌之间的因果关系
Fan Liu,Liqin Gan,Xueyao Cai et al.
Fan Liu et al.