Analysis of clinicopathological features, treatment modalities, and survival outcomes in advanced gastric and colorectal signet ring cell carcinoma [0.03%]
印戒细胞癌的临床病理特征、治疗方式及预后分析：胃癌与结直肠癌的对比研究
Jie Xu,Luojie Liu,Zhaoji Zhu
Jie Xu
Background: Advanced gastric and colorectal signet ring cell carcinoma (SRCC) exhibit distinct biological behaviors, yet comprehensive characterization of their clinicopathological features, treatment modalities, and surv...
Emerging small molecule strategies target cancer stem cells through ferroptosis and metabostemness [0.03%]
新兴小分子策略通过铁死亡和代谢肿瘤干细胞性靶向癌症干细胞
Husni Farah,Waleed K Abdulsahib,Sajida Hussein Ismael et al.
Husni Farah et al.
Prognostic value of brown adipocyte-related genes in colorectal cancer: a multi-omics and Mendelian randomization study [0.03%]
棕色脂肪细胞相关基因在结直肠癌中的预后价值：一项多组学和孟德尔随机化研究
HuaSheng He,Yuanbiao Wang,Huilan Kuang et al.
HuaSheng He et al.
Background: Brown adipocytes are vital in cancer's emergence and progression. However, such significance of brown adipocytes-related genes (BARGs) in colorectal cancer (CRC) still awaits exploration. The potential prognos...
Investigating the causal relationship between insomnia and ovarian cancer risk: a Mendelian randomization study [0.03%]
失眠与卵巢癌风险的因果关系研究：一项孟德尔随机化研究
Yuan Ren,Ni Yang,Tingyan Shi et al.
Yuan Ren et al.
Background: The epidemiological association between insomnia and ovarian cancer remains controversial, as observational studies are inherently susceptible to confounding factors and reverse causation bias. While neuroendo...
Endoplasmic reticulum stress-related genes play a role in the prognosis of lung adenocarcinoma [0.03%]
内质网应激相关基因在肺腺癌预后中的作用
Mingming Tang,Shi Zhang,Xingni Zhou et al.
Mingming Tang et al.
Background: Lung adenocarcinoma (LUAD) has a high mortality rate. The signaling of endoplasmic reticulum (ER) stress sensor can regulate cancer progression. We aimed to investigate the relationship between ER stress-relat...
Impact of lymph node yield on survival of patients with metastatic esophageal cancer: a population-based retrospective study [0.03%]
淋巴结采样数量对转移性食管癌患者生存期影响的基于人群的回顾性研究
Bo Chen,Yuze Zhao,Haitao Li et al.
Bo Chen et al.
Background: Esophageal cancer is the seventh most common cancer worldwide, and its related mortality remains high. The association between lymph node yield and survival outcomes in patients with distant lymph node metasta...
The role of neddylation in colorectal cancer and its therapeutic potential [0.03%]
Nedd8泛素化修饰在结直肠癌中的作用及其治疗潜力
Chen Mi,Feng Cui,Siyang Wang et al.
Chen Mi et al.
Integrative analysis reveals NFIL3 as a prognostic marker in glioblastoma associated with anesthesia and circadian rhythm genes [0.03%]
整合分析显示NFIL3是与麻醉和昼夜节律基因相关的胶质母细胞瘤预后标志物
Ye Yuan,Fuxin Lang,Juanjuan Huang et al.
Ye Yuan et al.
Background: Glioblastoma (GBM) is the most aggressive and common form of malignant brain tumor in adults, characterized by poor prognosis and limited treatment options. The molecular mechanisms underlying GBM pathogenesis...
VAL-083 is effective in patients with newly-diagnosed MGMT-unmethylated glioblastoma: report of phase II study [0.03%]
VAL-083可有效治疗MGMT原发 unmethylated胶质母细胞瘤患者：Ⅱ期临床试验报告
Chengcheng Guo,Qunying Yang,Meiling Deng et al.
Chengcheng Guo et al.
Purpose: Unmethylated MGMT is a validated biomarker for temozolomide (TMZ) resistance and poor prognosis in glioblastoma. VAL-083 (dianhydrogalactitol; DAG) is a DNA-targeting agent that forms interstrand crosslinks at O6...
A dosimetric correlation between the bladder filling volume and its effects on radiation dose during high-dose-rate intracavitary brachytherapy in patients with cervical cancer [0.03%]
膀胱充盈体积与高剂量率腔内组织间照射时膀胱受照剂量的关系研究
Lingqin Ni,Luqi Li,De Li et al.
Lingqin Ni et al.
Background: The purpose of this study was to establish a dosimetric correlation between the bladder filling volume and its effects on the dose received by the organs at risk (OARs) (bladder, rectum, sigmoid colon and smal...