Oxaliplatin upregulates Cyr61 expression by inhibiting the Hippo-YAP pathway which contributes to drug resistance of colorectal cancer cells [0.03%]
奥沙利铂通过抑制Hippo-YAP信号通路诱导CCN1表达增加从而促进结肠癌耐药性产生
Pingxia Lu,Cuifeng Zheng,Jingling Zhang et al.
Pingxia Lu et al.
Background: Oxaliplatin (OXA) resistance poses a significant challenge to the efficacy of chemotherapy for advanced colorectal cancer (CRC). This study aimed to elucidate the role of OXA in regulating Cysteine-rich protei...
RAD54B as a biomarker for prognosis and immunotherapy response in bladder cancer [0.03%]
RAD54B作为预后和免疫治疗反应的生物标志物在膀胱癌中的作用
Qingkai Lu,Jun Guo,Yuanyuan Xu et al.
Qingkai Lu et al.
MicroRNA-mediated modulation of cancer-associated fibroblasts in HER2-positive breast tumor microenvironment: a comprehensive review [0.03%]
HER2阳性乳腺肿瘤微环境中microRNA介导的癌相关成纤维细胞调控：全面综述
Mustafa T Ardah,Waleed K Abdulsahib,Hasanain Amer Naji et al.
Mustafa T Ardah et al.
The intricate interplay within the tumor microenvironment (TME) significantly dictates the trajectory of cancer progression and therapeutic response. In HER2-positive breast cancer, a particularly aggressive subtype, cancer-associated fibro...
The research landscape and future of targeting super-enhancers for cancer therapy: a bibliometric analysis [0.03%]
针对癌症治疗的超级增强子靶向研究格局与未来展望：文献计量分析
Wenhao Sun,Yupeng Hu,Tianjun Lan et al.
Wenhao Sun et al.
Background: Super-enhancers are specialized transcriptional regulatory elements pivotal for establishing and maintaining cell identity. Since their identification in 2013, SEs have garnered considerable attention as promi...
The value of immunogenic cell death-related gene model in the prognosis of gastric cancer [0.03%]
免疫源性细胞死亡相关基因模型在胃癌预后中的价值分析
Yakun Lang,Xiao-Yan Wang,Ziyan Liu et al.
Yakun Lang et al.
Immunogenic cell death (ICD) is a form of regulatory cell death that has been obtained growing attention for its role in the treatment and prognosis of tumors. This study aims to further investigate the value of immunogenic cell death-relat...
Lidawani Lambuk,Muhammad Zulfiqah Sadikan,Mohd Aizuddin Mohd Lazaldin et al.
Lidawani Lambuk et al.
The role of microRNAs in modulating Wnt signaling pathway dynamics and their therapeutic implications in non-small cell lung cancer [0.03%]
microRNA在调节Wnt信号通路动态及其在非小细胞肺癌治疗中的作用与意义
Yahui Wang,Saodat Yarmukhamedova,Rawaa Najim Alkhamessi et al.
Yahui Wang et al.
Lung cancer ranks as the second most prevalent cancer worldwide and exhibits the highest mortality rate among all cancers. It primarily consists of two subtypes: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), with NSC...
Deciphering RNA and protein expression discordance identifies TOP2A as a prognostic biomarker and potential therapeutic target in lung adenocarcinoma [0.03%]
解析RNA和蛋白质表达不一致可鉴定TOP2A作为肺腺癌预后生物标志物和潜在治疗靶点
Mika Miyabe,Shuntaro Arimitsu,Amina Bolatkan et al.
Mika Miyabe et al.
Objective: Understanding the discordance between RNA and protein expression can help elucidate underlying disease mechanisms that cannot be fully explained using transcriptomic information alone. Unveiling novel mechanism...
Systemic analysis of 1,4-dichlorobenzenes effects on lung adenocarcinoma environmental exposure and core target regulation prediction [0.03%]
系统分析1,4-二氯苯对肺腺癌的环境暴露效应及核心靶点调控预测研究
Bingfeng Ma,Juan Hu,Dingfei Ren et al.
Bingfeng Ma et al.