A Self-Adapting Polygenic Risk Score Model Improves Risk Prediction of Venous Thromboembolism in Han Chinese Cohorts [0.03%]
一种自我调节的多基因风险评分模型可提高在汉族人群中静脉血栓栓塞风险预测的效果
Zhaoman Wan,Zhu Zhang,Mingming Su et al.
Zhaoman Wan et al.
Most genome-wide association studies (GWAS) of Venous Thromboembolism (VTE) have used data from individuals of European descent, however, genetic factors for VTE have not been fully identified in Chinese populations, which causes the limite...
Stratification by Mutational Landscape Reveals Differential Immune Infiltration and Predicts the Recurrence and Clinical Outcome of Cervical Cancer [0.03%]
基于突变谱系的分层揭示了宫颈癌中不同的免疫浸润并预测其复发和临床结果
Chun Gao,Qian Zhou,Liting Liu et al.
Chun Gao et al.
Cervical cancer (CC) is the second most common cancer of female reproductive system. However, satisfactory prognostic model for CC remains to be established. In this study, we perform whole-exome sequencing on formalin-fixed and paraffin-em...
SIMPLE: A One-Pot RPA-Cas12b Method for Single Nucleotide Variations Identification with an Expanded Scope and Clinical Applications [0.03%]
简单的RPA-Cas12b基因分型技术（方法）：扩大范围的单核苷酸变异鉴定及临床应用
Kaiming Guo,Yongkang Lai,Yiru Han et al.
Kaiming Guo et al.
Rapid and reliable nucleic acid detection methods are essential in clinical diagnostics and biotechnology. The clustered regularly interspaced short palindromic repeats (CRISPR) system is emerging as a next-generation nucleic acid detection...
Association Between Healthy Lifestyles and Adverse Health Outcomes, and the Mediating Role of Inflammation [0.03%]
健康生活方式与不良健康结果之间的关联及其炎症介导作用
Jingyi Wu,Yaqi Huang,Shuishan Zhang et al.
Jingyi Wu et al.
Cohort Profile: Precision Environmental Health Cohort of Healthy Undergraduates [0.03%]
精准环境健康大学生队列研究
Yanbing Li,Yayuan Mei,Jiaxin Zhao et al.
Yanbing Li et al.
The Impact of Lipase H Deficiency on Gut Aging and Lifespan in Drosophila [0.03%]
果蝇肠道衰老和寿命的脂酶H缺乏症的影响研究
Ayesha Nisar,Sawar Khan,Yonghan He
Ayesha Nisar
Identification of a Novel Pyroptosis-Related lncRNAs Prognosis Model and Subtypes in Ovarian Cancer [0.03%]
识别出一个新的与焦亡相关的长链非编码RNA预后模型及卵巢癌亚型
Xiao-Feng Xie,Xiao-Qian Hu,Deng-Xiang Liu et al.
Xiao-Feng Xie et al.
Ovarian cancer (OC), a predominant gynecological malignancy, has consistently showcased grim prognostic outcomes. This investigation delves into the emerging field of pyroptosis and the intricacies of long non-coding RNAs (lncRNAs), specifi...
Amyotrophic Lateral Sclerosis and Risk of Common Cancer: Mendelian Randomization Interrogation of Causality and Mediation [0.03%]
肌萎缩侧索硬化与常见癌症风险的孟德尔随机化研究因果关系及中介效应
Xiaoxue Tan,Gaifen Liu,Xiangnan Li et al.
Xiaoxue Tan et al.
Compared with the well-documented inverse comorbidity of common neurodegenerative diseases with some types of cancer, the association of amyotrophic lateral sclerosis (ALS) with cancer was obscure. This Mendelian randomization (MR) analysis...
Baseline Plasma GPX3 Level Predicts Efficacy of Insulin-Sensitization Drug Chiglitazar in Type 2 Diabetes [0.03%]
基线血浆GPX3水平能够预测2型糖尿病患者胰岛素增敏药物齐拉西舒的效果
Zehui Cao,Haonan Chen,Qiaochu Chen et al.
Zehui Cao et al.