Investigating the Mechanisms of Combined Therapy for MCF-7 Breast Cancer Cells Using Arsenic Trioxide and Resveratrol through Network Pharmacology [0.03%]
网络药理学联合应用三氧化二砷和白藜芦醇治疗MCF-7乳腺癌细胞的机制研究
Hongye Hu,Yanzhi Wu,Jingwei Hong et al.
Hongye Hu et al.
Breast cancer (BC) remains the predominant form of cancer among women. Arsenic trioxide (ATO), an element in traditional Chinese medicine, has shown potential for treating BC, particularly when combined with resveratrol. However, the exact ...
Immunophenotyping of Mouse Colonic Unconventional T Cells by Mapping Cell Phenomics With 22-Color Flow Cytometry Assays [0.03%]
应用22色流式细胞检测绘制小鼠结肠非典型T细胞免疫表型素地图谱
Lehan Pan,Chunting Shen,Shiyang Huang et al.
Lehan Pan et al.
The intestinal epithelium is continually exposed to food-derived antigens and microbiota. This continual exposure requires a delicate immune homeostasis for food tolerance and protection against infection. Unconventional T lymphocytes, incl...
Retinol-driven Gene Signatures Predict Lung Adenocarcinoma Outcomes and Highlight PAICS as a Therapeutic Opportunity [0.03%]
视黄醇驱动的基因特征可预测肺腺癌预后并凸显PAICS的治疗价值
Guangyao Shan,Binyang Pan,Yongxing Zhang et al.
Guangyao Shan et al.
Retinol, a pivotal regulator of cellular growth and apoptosis, has garnered substantial attention for its intricate involvement in cancer development. To explore Vitamin A's impact on lung adenocarcinoma (LUAD), we utilized comprehensive da...
Quantifying Individual Health Status from Multi-omics Data by Health State Manifold [0.03%]
基于健康状态流形的多组学个体健康量化研究
Xinyan Zhang,Chengming Zhang,Yanpu Wu et al.
Xinyan Zhang et al.
Quantifying individual health status from increasingly accumulated omics data is essential for both early prevention and intervention of diseases, which attracts great attention from communities of biology and medicine. Most of the existing...
Association Between Primary Dysmenorrhea and Mental Health Traits: A Study Based on Multi-Phenotype Correlation Network and Mendelian Randomization Analysis in Female College Students [0.03%]
经期疼痛与心理健康特征之间的关联：基于多表型相关网络和孟德尔随机化分析的女大学生研究
Huiting Jiangzhou,Hanpeng Xu,Yanqin Wen et al.
Huiting Jiangzhou et al.
Primary dysmenorrhea (PDM) is a common cyclic menstrual pain that significantly affects the quality of life for women. Several epidemiological studies have suggested a potential association between PDM and mental health traits, including st...
Mendelian Randomization Combined with Bioinformatics Revealed Specific Allergy-Mediated Protective Mechanisms Against Renal Cell Carcinoma [0.03%]
孟德尔随机化结合生物信息学揭示了特异性过敏介导的肾细胞癌保护机制
Zixuan Xing,Hao Lei,Yaohui Jiang et al.
Zixuan Xing et al.
There is evidence that allergic diseases are associated with carcinogenesis. According to translational and epidemiological data, it appears that different cancer types yield different associations. We investigated the relationship between ...
Protocol for Retinal Imaging and Extraction of Imaging-Derived Phenotypes from the Chinese Human Phenome Project [0.03%]
中国人表型组计划眼底照相的方案及建立基于影像的表型特征标准集
Lizhen Lan,Binxin Xu,Zhiqiang Yan et al.
Lizhen Lan et al.
Retinal imaging is pivotal in the evaluation of ocular and systemic health, presenting significant promise for extensive population studies. However, the lack of standardized and automated techniques for extracting Imaging-Derived Phenotype...