Pan-cancer analysis identifies RNA helicase DDX1 as a prognostic marker [0.03%]
泛癌分析鉴定RNA解旋酶DDX1为预后标志物
Baocai Gao,Xiangnan Li,Shujie Li et al.
Baocai Gao et al.
The DEAD-box RNA helicase (DDX) family plays a critical role in the growth and development of multiple organisms. DDX1 is involved in mRNA/rRNA processing and mature, virus replication and transcription, hormone metabolism, tumorigenesis, a...
A Preliminary Study on the Evaluation of Human Sperm Head Morphology with a Domestic Digital Holographic Image System [0.03%]
国产数字全息显微平台的人精液头部形态评价初步研究
Hong Zhu,Yong Zhu,Can Sun et al.
Hong Zhu et al.
The head of sperm was imaged with domestic digital holographic microscopy (DHM), and then the quantitative three-dimensional size information of normal sperm and teratozoospermic sperm was compared and analyzed. DHM sperm imaging and repeat...
Emerging Regulatory Mechanisms of N6-Methyladenosine Modification in Cancer Metastasis [0.03%]
癌症转移中N6-甲基腺苷修饰的新兴调控机制
Jing Zhao,Hao Xu,Yinghan Su et al.
Jing Zhao et al.
Cancer metastasis is the major cause of cancer-related deaths and accounts for poor therapeutic outcomes. A metastatic cascade is a series of complicated biological processes. N6-methyladenosine (m6A) is the most abundant and conserved epit...
Junjie Luo,Shiwei Shen,Jingjing Xia et al.
Junjie Luo et al.
The concept of Yang Qi in Traditional Chinese Medicine (TCM) has many similarities with mitochondria in modern medicine. Both are indispensable to human beings and closely related to life and death. This article discusses the similarities i...
Basic Phenotyping of Male Fertility from 2019 to 2020 at the Human Sperm Bank of Fudan University [0.03%]
复旦大学人类精子库2019-2020年人类精液标本基本质控指标分析
Yadong Li,Can Sun,Haitao Ma et al.
Yadong Li et al.
The aim of this cross-sectional survey was to analyze the semen parameters of volunteers from the Human Sperm Bank of Fudan University, as well as the related factors influencing these parameters. From January 2019 to December 2020, semen p...
Deep Clinical Phenotyping of Parkinson's Disease: Towards a New Era of Research and Clinical Care [0.03%]
帕金森病的深度临床分型：开启研究和临床护理的新时代
Zhiheng Xu,Bo Shen,Yilin Tang et al.
Zhiheng Xu et al.
Despite recent advances in technology, clinical phenotyping of Parkinson's disease (PD) has remained relatively limited as current assessments are mainly based on empirical observation and subjective categorical judgment at the clinic. A la...
Yang Liu,Haichu Zhao,Boqiang Fu et al.
Yang Liu et al.
Phenomics explores the complex interactions among genes, epigenetics, symbiotic microorganisms, diet, and environmental exposure based on the physical, chemical, and biological characteristics of individuals and groups. Increasingly efficie...
N-Glycoproteomics Study of Putative N-Glycoprotein Biomarkers of Drug Resistance in MCF-7/ADR Cells [0.03%]
用于研究MCF-7/ADR细胞中潜在的耐药糖蛋白生物标志物的N-糖蛋白组学研究
Hailun Yang,Feifei Xu,Kaijie Xiao et al.
Hailun Yang et al.
Currently, drug resistance of anti-cancer therapy has become the main cause of low survival rate and poor prognosis. Full understanding of drug resistance mechanisms is an urgent request for further development of anti-cancer therapy and im...
A Hashing-Based Framework for Enhancing Cluster Delineation of High-Dimensional Single-Cell Profiles [0.03%]
一种基于哈希的框架，可增强高维单细胞谱型的聚类区分度
Xiao Liu,Ting Zhang,Ziyang Tan et al.
Xiao Liu et al.
Although many methods have been developed to explore the function of cells by clustering high-dimensional (HD) single-cell omics data, the inconspicuously differential expressions of biomarkers of proteins or genes across all cells disturb ...
Pseudotime Ordering Single-Cell Transcriptomic of β Cells Pancreatic Islets in Health and Type 2 Diabetes [0.03%]
健康状况和2型糖尿病β细胞胰岛单细胞转录图的伪时间排序
Kaixuan Bao,Zhicheng Cui,Hui Wang et al.
Kaixuan Bao et al.
β cells are defined by the ability to produce and secret insulin. Recent studies have evaluated that human pancreatic β cells are heterogeneous and demonstrated the transcript alterations of β cell subpopulation in diabetes. Single-cell ...