Positron Emission Tomography Molecular Imaging for Phenotyping and Management of Lymphoma [0.03%]
正电子发射断层扫描分子影像在淋巴瘤表型和管理中的应用
Xiaohui Zhang,Han Jiang,Shuang Wu et al.
Xiaohui Zhang et al.
Positron emission tomography (PET) represents molecular imaging for non-invasive phenotyping of physiological and biochemical processes in various oncological diseases. PET imaging with 18F-fluorodeoxyglucose (18F-FDG) for glucose metabolis...
A Meta-Analysis of the Genome-Wide Association Studies on Two Genetically Correlated Phenotypes Suggests Four New Risk Loci for Headaches [0.03%]
针对两种遗传相关表型的全基因组关联研究荟萃分析发现了四种新的头痛易感位点
Weihua Meng,Parminder S Reel,Charvi Nangia et al.
Weihua Meng et al.
Headache is one of the commonest complaints that doctors need to address in clinical settings. The genetic mechanisms of different types of headache are not well understood while it has been suggested that self-reported headache and self-re...
Causal Association of Cardiac Function by Magnetic Resonance Imaging with Frailty Index: A Mendelian Randomization Study [0.03%]
基于磁共振的心脏功能与脆弱指数的因果关联：一项孟德尔随机化研究
Hui Zhang,Meng Hao,Zixin Hu et al.
Hui Zhang et al.
Owing to the susceptibility of conventional observational studies to confounding factors and reverse causation, the causal association between cardiac function and frailty is unclear. We aimed to investigate whether cardiac function has cau...
Measurement of Cerebral Oxygen Extraction Fraction Using Quantitative BOLD Approach: A Review [0.03%]
基于定量血氧水平依赖方法的脑氧提取分数测量研究进展
Hongwei Li,Chengyan Wang,Xuchen Yu et al.
Hongwei Li et al.
Quantification of brain oxygenation and metabolism, both of which are indicators of the level of brain activity, plays a vital role in understanding the cerebral perfusion and the pathophysiology of brain disorders. Magnetic resonance imagi...
Dopaminergic Dysfunction and Glucose Metabolism Characteristics in Parkin-Induced Early-Onset Parkinson's Disease Compared to Genetically Undetermined Early-Onset Parkinson's Disease [0.03%]
Parkin诱导的早发性帕金森病与遗传不明原因早发性帕金森病的多巴胺功能及糖代谢特征比较研究
Feng-Tao Liu,Jia-Ying Lu,Yi-Min Sun et al.
Feng-Tao Liu et al.
While early-onset Parkinson's disease (EOPD) caused by mutations in the parkin gene (PRKN) tends to have a relatively benign course compared to genetically undetermined (GU)-EOPD, the exact underlying mechanisms remain elusive. We aimed to ...
Seasonality and Sex-Biased Fluctuation of Birth Weight in Tibetan Populations [0.03%]
藏族人口出生体重的季节性和性别差异波动
Yaoxi He,Jun Li,Tian Yue et al.
Yaoxi He et al.
Birth weight (BW) is a key determinant of infant mortality. Previous studies have reported seasonal fluctuation of BW. However, the responsible environmental factors remain disputable. High-altitude environment provides a great opportunity ...
Preoperative Characteristics of Ocular Biometry in Children with Unilateral Congenital Cataracts [0.03%]
先天性单眼性白内障儿童的术前生物测量特征分析
Jiahui Chen,Yating Tang,Yongxiang Jiang et al.
Jiahui Chen et al.
The ocular biometry characteristics are clinically significant for children with unilateral congenital cataracts, but there is a lack of data analysis concerning the preoperative measurements. The axial length (AL), mean keratometry (Km), c...
Li Jin
Li Jin
Computational Methods for Prediction of Human Protein-Phenotype Associations: A Review [0.03%]
人类蛋白质表型关联预测的计算方法综述
Lizhi Liu,Shanfeng Zhu
Lizhi Liu
Deciphering the relationship between human proteins (genes) and phenotypes is one of the fundamental tasks in phenomics research. The Human Phenotype Ontology (HPO) builds upon a standardized logical vocabulary to describe the abnormal phen...
Plasma Lipidomic Subclasses and Risk of Hypertension in Middle-Aged and Elderly Chinese [0.03%]
中国中老年人血浆脂质组亚类与高血压发病风险关联的前瞻性研究
Zhenhua Niu,Qingqing Wu,Yaogan Luo et al.
Zhenhua Niu et al.
While disrupted lipid metabolism is a well-established risk factor for hypertension in animal models, the links between various lipidomic signatures and hypertension in human studies remain unclear. We aimed to examine associations between ...