High Arterial Oxygen Saturation in the Acclimatized Lowlanders Living at High Altitude [0.03%]
长期居住在高原的低landers高动脉血氧饱和度
Yaoxi He,Chaoying Cui,Yongbo Guo et al.
Yaoxi He et al.
Blood oxygen saturation (SpO2) is a key indicator of oxygen availability in the body. It is known that a low SpO2 at high altitude is associated with morbidity and mortality risks due to physiological hypoxemia. Previously, it was proposed ...
DBLiPro: A Database for Lipids and Proteins in Human Lipid Metabolism [0.03%]
DBLiPro：人类脂质代谢中脂质和蛋白质的数据库
Qian Wu,Yuanyuan Huang,Xiangya Kong et al.
Qian Wu et al.
To help researchers in the field of biology, medicine, chemistry, and materials science to use lipidomic data conveniently, there is an urgent need to develop a platform that provides a systematic knowledgebase of human lipid metabolism and...
Genetic Phenotypes of Alzheimer's Disease: Mechanisms and Potential Therapy [0.03%]
阿尔茨海默病的遗传表型：机制及潜在治疗手段
Meina Quan,Shuman Cao,Qi Wang et al.
Meina Quan et al.
Years of intensive research has brought us extensive knowledge on the genetic and molecular factors involved in Alzheimer's disease (AD). In addition to the mutations in the three main causative genes of familial AD (FAD) including presenil...
Minghui Liu,Hangyu Zhu,Jinbu Tang et al.
Minghui Liu et al.
A standard operating procedure for studying the sleep phenotypes in a large population cohort is proposed. It is intended for academic researchers in investigating the sleep phenotypes in conjunction with the clinical sleep disorders assess...
Deep Immunophenotyping of Human Whole Blood by Standardized Multi-parametric Flow Cytometry Analyses [0.03%]
人全血标准多参数流式细胞分析的深入免疫表型测定
Jian Gao,Yali Luo,Helian Li et al.
Jian Gao et al.
Immunophenotyping is proving crucial to understanding the role of the immune system in health and disease. High-throughput flow cytometry has been used extensively to reveal changes in immune cell composition and function at the single-cell...
Deep Learning-Assisted Quantitative Susceptibility Mapping as a Tool for Grading and Molecular Subtyping of Gliomas [0.03%]
基于深度学习的定量磁敏感加权像在胶质瘤分级及分子亚型鉴别中的应用
Wenting Rui,Shengjie Zhang,Huidong Shi et al.
Wenting Rui et al.
This study aimed to explore the value of deep learning (DL)-assisted quantitative susceptibility mapping (QSM) in glioma grading and molecular subtyping. Forty-two patients with gliomas, who underwent preoperative T2 fluid-attenuated invers...
A Genome-Wide Association Study for Susceptibility to Axial Length in Highly Myopic Eyes [0.03%]
高度近视眼轴长度易感性的全基因组关联研究
Qiang Lu,Yu Du,Ye Zhang et al.
Qiang Lu et al.
High myopia has long been highly prevalent worldwide with a largely yet unexplained genetic contribution. To identify novel susceptibility genes for axial length (AL) in highly myopic eyes, a genome-wide association study (GWAS) was perform...
Yilian Liu,Wanglei Zhong,Xiao Li et al.
Yilian Liu et al.
The gut microbiota refers to the gross collection of microorganisms, estimated trillions of them, which reside within the gut and play crucial roles in the absorption and digestion of dietary nutrients. In the past decades, the new generati...
RNA-Sequencing Reveals Gene Expression and Pathway Signatures in Umbilical Cord Blood Affected by Birth Delivery Mode [0.03%]
基于RNA测序探讨分娩方式对脐带血基因表达及信号通路的影响
Yongjie Liu,Kun Sun,Yuexin Gan et al.
Yongjie Liu et al.
Cesarean section (CS) confers increased risk of type I diabetes, asthma, inflammatory bowel disease, celiac disease, overweight and obesity, etc., in the offspring. However, the underlying mechanism remains unknown. To investigate the influ...
Lu Pan,Chenqing Zheng,Zhijian Yang et al.
Lu Pan et al.
Alternative splicing exists in most multi-exonic genes, and exploring these complex alternative splicing events and their resultant isoform expressions is essential. However, it has become conventional that RNA sequencing results have often...