Mycobacteriaceae Phenome Atlas (MPA): A Standardized Atlas for the Mycobacteriaceae Phenome Based on Heterogeneous Sources [0.03%]
结核分枝杆菌表型图谱(MPA)：基于非同源数据的结核分枝杆菌表型标准化图谱
Wan Liu,Hui Cen,Zhile Wu et al.
Wan Liu et al.
The bacterial family Mycobacteriaceae includes pathogenic and nonpathogenic bacteria, and systematic research on their genome and phenome can give comprehensive perspectives for exploring their disease mechanism. In this study, the phenotyp...
A Common Functional Variant at the Enhancer of the Rheumatoid Arthritis Risk Gene ORMDL3 Regulates its Expression Through Allele-Specific JunD Binding [0.03%]
风湿性关节炎风险基因ORMDL3增强子的常见功能变异体通过等位基因特异性JunD结合调控其表达
Wenjing Ye,Yiyun Yu,Xiaoxia Zhu et al.
Wenjing Ye et al.
Genome-wide association studies (GWASs) have identified over 100 loci associated with rheumatoid arthritis (RA); however, the functionally affected genes and the underlying molecular mechanisms contributing to these associations are often u...
Inflammation as a Mediator of Microbiome Dysbiosis-Associated DNA Methylation Changes in Gastric Premalignant Lesions [0.03%]
胃癌前病变中炎症介导的微生物群失调相关的DNA甲基化变化
Lingjun Yan,Wanxin Li,Fenglin Chen et al.
Lingjun Yan et al.
Evidence for the influence of chronic inflammation induced by microbial dysbiosis on aberrant DNA methylation supports a plausible connexion between disordered microbiota and precancerous lesions of gastric cancer (PLGC). Here, a comprehens...
α2,3-Sialylation with Fucosylation Associated with More Severe Anti-MDA5 Positive Dermatomyositis Induced by Rapidly Progressive Interstitial Lung Disease [0.03%]
由快速进展性间质性肺疾病诱导的抗MDA5阳性皮肌炎中与岩藻糖基化相关的α2,3-唾液酸化与更严重的临床症状相关
Rongrong Zhang,Li Guo,Jichen Sha et al.
Rongrong Zhang et al.
Dermatomyositis (DM) is a heterogeneous autoimmune disease associated with numerous myositis specific antibodies (MSAs) in which DM with anti-melanoma differentiation-associated gene 5-positive (MDA5 + DM) is a unique subtype of DM with hig...
Infrared Imageries of Human Body Activated by Tea Match the Hypothesis of Meridian System [0.03%]
饮茶激发的人体红外图像符合经络系统假说
Wenli Jin,Yichen Tao,Chen Wang et al.
Wenli Jin et al.
Human meridian (Jingluo) system was hypothesized by traditional Chinese medicine (TCM) for thousands of years, suggesting 12 normal meridian channels going through respective organs, carrying fluid and energy, and laying thermal effects. So...
A Protocol for Digitalized Collection of Traditional Chinese Medicine (TCM) Pulse Information Using Bionic Pulse Diagnosis Equipment [0.03%]
一种使用仿生脉诊设备进行中医脉象信息数字化采集的协议
Xing Zhu,Fanyu Wang,Jian Mao et al.
Xing Zhu et al.
Pulse diagnosis equipment used in Traditional Chinese Medicine (TCM) has long been developed for collecting pulse information and in TCM research. However, it is still difficult to implement pulse taking automatically or efficiently in clin...
Immune-Ageing Evaluation of Peripheral T and NK Lymphocyte Subsets in Chinese Healthy Adults [0.03%]
中国健康成人外周T和NK淋巴细胞亚群的免疫衰老评价
Zhenghu Jia,Zhiyao Ren,Dongmei Ye et al.
Zhenghu Jia et al.
Ageing is often accompanied with a decline in immune system function, resulting in immune ageing. Numerous studies have focussed on the changes in different lymphocyte subsets in diseases and immunosenescence. The change in immune phenotype...
Integrative Identification by Hi-C Revealed Distinct Advanced Structural Variations in Lung Adenocarcinoma Tissue [0.03%]
基于Hi-C数据集整合分析鉴定出肺腺癌中独特的高级结构变异
Tingting Song,Menglin Yao,Ying Yang et al.
Tingting Song et al.
Advanced three-dimensional structure variations of chromatin in large genome fragments, such as conversion of A/B compartment, topologically associated domains (TADs) and chromatin loops are related closely to occurrence of malignant tumors...
International Nuclear Medicine Consensus on the Clinical Use of Amyloid Positron Emission Tomography in Alzheimer's Disease [0.03%]
国际核医学阿尔茨海默病淀粉样PET临床应用共识
Mei Tian,Chuantao Zuo,Ali Cahid Civelek et al.
Mei Tian et al.
Alzheimer's disease (AD) is the main cause of dementia, with its diagnosis and management remaining challenging. Amyloid positron emission tomography (PET) has become increasingly important in medical practice for patients with AD. To integ...
Virtual Fluorescence Translation for Biological Tissue by Conditional Generative Adversarial Network [0.03%]
基于条件生成对抗网络的生物组织虚拟荧光转换技术
Xin Liu,Boyi Li,Chengcheng Liu et al.
Xin Liu et al.
Fluorescence labeling and imaging provide an opportunity to observe the structure of biological tissues, playing a crucial role in the field of histopathology. However, when labeling and imaging biological tissues, there are still some chal...