Aggressive pituitary tumors and carcinomas: medical treatment beyond temozolomide [0.03%]
超越替莫唑胺的侵袭性垂体肿瘤和癌的药物治疗
Dario DE Alcubierre,Anna L Carretti,François Ducray et al.
Dario DE Alcubierre et al.
Aggressive pituitary tumors are a subset of pituitary neoplasms, characterized by unusually fast growth rate, invasiveness and overall resistance to optimized standard treatment. When metastases are present, the term pituitary carcinoma is ...
Association between circulating betatrophin levels and T2DM: A meta-analysis [0.03%]
循环贝塔细胞生长因子与T2DM关系的Meta分析研究
Yuquan Zhan
Yuquan Zhan
Introduction: The association between betatrophin level and type 2 diabetes mellitus (T2DM) is a subject of controversy, and the reasons for conflicting results have been poorly explained. To address this gap, we conducte...
Exploring the potential impact of GLP-1 receptor agonists in cancer therapy [0.03%]
GLP-1受体激动剂在癌症治疗中的潜在影响探索
Baseer Aslam,Muhammad D Bin Zafar,Mah I Khan Changez et al.
Baseer Aslam et al.
Glucagon-like peptide-1 (GLP-1) receptor agonists are used in diabetes management and can have a potential application in cancer therapy. While their involvement in cancer treatment is still being studied, recent research suggests they may ...
Osamu Takahashi,Ryuji Sakakibara,Setsu Sawai
Osamu Takahashi
Update on the ZNT8 epitope and its role in the pathogenesis of type 1 diabetes [0.03%]
ZNT8表位及其在1型糖尿病发病机制中的作用的最新研究进展
Liu Yang,Xuejiao Zhang,Qing Liu et al.
Liu Yang et al.
Type 1 diabetes (T1D) is an organ-specific chronic autoimmune disease mediated by autoreactive T cells. ZnT8 is a pancreatic islet-specific zinc transporter that is mainly located in β cells. It not only participates in the synthesis, stor...
Nucleobindin-2 derived nesfatin-1 in polycystic ovary syndrome: a PRISMA and GRADE-compliant systematic review and meta-analysis with diagnostic test accuracy [0.03%]
多囊卵巢综合征中核结合蛋白-2衍生的nesfatin-1：符合PRISMA和GRADE系统的系统回顾及荟萃分析与诊断试验准确度评估
Konda Venkata Nagaraju,Mona Lisa,Seshadri Reddy Varikasuvu et al.
Konda Venkata Nagaraju et al.
Introduction: Nesfatin-1 is a satiety peptide secreted by central, peripheral nervous system and some peripheral tissues. This meta-analysis was conducted to explore the associations with diagnostic accuracy of circulator...
Laura Cimino,Andrea Crafa,Rossella Cannarella et al.
Laura Cimino et al.
Background: Incorrect or harmful lifestyle during youth may impact negatively gonadal function later in life. To reduce the development of risky behaviors a series of health prevention and intervention campaigns have been...
Intermittent fasting: a new trend or a valid approach for the treatment of obesity? [0.03%]
间歇性禁食：一种新的流行趋势还是治疗肥胖的有效方法？
Giuseppe Annunziata,Xavier Capó,Giovanna Muscogiuri et al.
Giuseppe Annunziata et al.
Serum kisspeptin is higher in hypertensive than non-hypertensive female subjects and positively correlated with systolic blood pressure [0.03%]
高血压女性患者的血清亲吻肽高于非高血压组，并与收缩压呈正相关
Chantacha Sitticharoon,Yanint Raksadawan,Peerada Boonpuan et al.
Chantacha Sitticharoon et al.
Background: Kisspeptin has a major role in reproductive regulation. Furthermore, it is also involved in metabolic and cardiovascular regulation as well as is a potent vasoconstrictor. This study aimed to: 1) determine cor...
Obesity as a negative mediator of serine-118/serine-105 phosphorylation sites on ERα/ERβ through the ovarian cycle [0.03%]
肥胖通过卵巢周期负向调控雌激素受体α/β Ser118/Ser105磷酸化位点的作用机制研究
Ricardo E Ramírez-Orozco,Juan M Malacara,Nicté Figueroa-Vega
Ricardo E Ramírez-Orozco