Efficacy and safety of oral semaglutide as add-on therapy in poorly controlled type 2 diabetes on background SGLT2 inhibitors: a real-world, multi-center, retrospective, observational study (RYS2) [0.03%]
口服司美格鲁肽作为二线药物治疗二甲双胍和SGLT-2抑制剂控制不佳的2型糖尿病患者的有效性和安全性:一项真实世界、多中心、回顾性、观察性研究(RYSTON 2)
Maria E Malighetti,Fabio Vescini,Maria Carpentieri et al.
Maria E Malighetti et al.
Background: Treatment of type 2 diabetes mellitus (T2DM) relies on diverse glucose-lowering medications, championing sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists as viab...
Association between serum uric acid and abdominal fat distribution quantified by computed tomography in Korean men: a single center study of 5144 cases [0.03%]
韩国男性血清尿酸与腹部脂肪分布量化之间的关系:一项关于5144例的单中心研究
Sungwon Ko,Su-Jin Choi,Young-Jee Jeon et al.
Sungwon Ko et al.
Background: Serum uric acid (UA), the end product of purine metabolism, has been implicated in metabolic and cardiovascular diseases. While obesity, particularly visceral fat accumulation, is related with hyperuricemia, l...
Expert opinion by the Italian Society of Gynecology of the Third Age (SIGiTE) and the Italian Society of Menopause (SIM) on diagnosis and treatment of premature ovarian insufficiency [0.03%]
意大利老年妇科协会(SIGiTE)和更年期协会(SIM)关于早发性卵巢功能不全的诊断及治疗的专家意见
Anna Capozzi,Simona Ambroggio,Angelo Cagnacci et al.
Anna Capozzi et al.
Premature ovarian insufficiency (POI) is a critical condition affecting young women before the median age of menopause and consisting of spontaneous oligo-amenorrhea for at least four months associated with follicle stimulating hormone (FSH...
Genomic mapping of diabetic kidney disease biomarkers and identification of potential inhibitors through virtual screening [0.03%]
糖尿病肾脏疾病生物标志物的基因组定位及虚拟筛选潜在抑制剂
Yi Liu,Yu Wang
Yi Liu
Background: Diabetic kidney disease (DKD) is a common and serious complication of diabetes mellitus, marked by a multifactorial pathogenesis and the absence of sensitive diagnostic biomarkers. Identifying novel molecular ...
Giovanni Vitale
Giovanni Vitale
Effects of low protein diet supplemented with ketoanalogues on kidney function and nutritional outcomes in a nonagenarian population with advanced chronic kidney disease: a pilot study [0.03%]
低蛋白联合酮酸饮食对终末期慢性肾脏病晚期老年患者肾功能和营养状况影响的前瞻性队列研究
Giuseppe Annunziata,Teresa Marinelli,Armando Melfitano et al.
Giuseppe Annunziata et al.
Background: Ageing leads to an increase in the incidence of chronic diseases, including chronic kidney disease (CKD). The increasing proportion of elderly people with reduced renal function draws attention to a sub-popula...
Deciphering adrenal cysts: unveiling insights into imaging, histology, and optimal management approaches [0.03%]
肾上腺囊肿的诊断:揭示影像学、组织病理学及治疗方面的见解
Jan Calissendorff,C Christofer Juhlin,Anna Kistner et al.
Jan Calissendorff et al.
Adrenal cysts are rare lesions that are increasingly discovered incidentally during radiological examinations conducted without suspicion of adrenal disease. Typically benign, hormonally nonfunctional, and asymptomatic, these lesions may oc...
Catarina Regala,Tiago N Silva,Valeriano Leite
Catarina Regala
Introduction: Advanced and progressive thyroid cancer (TC) such as radioiodine-refractory thyroid cancer (RAIR-TC), presents a significant clinical challenge due to its poorer prognosis and limited therapeutic options. Le...
Vitamin D: beneficial effects and risk of intoxication: a public health problem [0.03%]
维生素D:有益作用和中毒风险:一个公共卫生问题
Lucia F Stefanelli,Martina Cacciapuoti,Dorella Del Prete et al.
Lucia F Stefanelli et al.
Associations between DXA-derived parameters of body composition and metabolic dysfunction-associated steatotic liver disease in patients with T2DM and prediabetic states [0.03%]
T2DM和糖尿病前期患者DXA衍生体质参数与代谢功能障碍相关脂肪性肝病的关联研究
Emil Fraenkel,Tomáš Koky,Samuel Štellmach et al.
Emil Fraenkel et al.
Background: Sarcopenic obesity is closely related to metabolic dysfunction-associated steatotic liver disease (MASLD), but the independent contributions of lean mass and fat mass components to MASLD are not well understoo...