Effects of testosterone undecanoate as add-on therapy in obese hypogonadal men that are late responders to tirzepatide: a pilot study [0.03%]
十一酸睾酮作为肥胖性性腺功能减退症晚期患者的附加疗法对曲前列尼尔的影响：一项试点研究
Giuseppe Seminara,Marco Leuzzi,Leonardo Meduri et al.
Giuseppe Seminara et al.
Background: Male obesity-associated hypogonadism promotes a vicious cycle of sarcopenic obesity and increased cardiometabolic risk. Although tirzepatide is highly effective for weight loss, a subset of "late responders" h...
Gut microbiota and metabolic syndrome in postmenopausal women: a narrative review of mechanisms and dietary recommendations [0.03%]
绝经后女性肠道菌群和代谢综合征的机制及膳食建议综述
Sebastián Chapela,Julieta Locatelli,Melannie Toral-Noristz et al.
Sebastián Chapela et al.
Menopause brings a series of endocrine changes that significantly increase the risk of developing metabolic syndrome (MetS), a condition characterized by central obesity, dyslipidemia, hypertension, and insulin resistance. In this context, ...
Role of microRNA in type 1 diabetes pathogenesis and their therapeutic potential [0.03%]
微小核糖核酸在1型糖尿病发病机制中的作用及其治疗潜能
Manar F Atoum,Ala&#x; S Almehsen,Dalia A Alowaisy
Manar F Atoum
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreatic islets, resulting in complete insulin deficiency. The pathogenesis of T1D is multifactorial and includes ...
Dioxin, an endocrine disruptor, induces long term effects on DNA methylation in men after in-utero exposure [0.03%]
孕期接触二恶英的内分泌干扰物对男性DNA甲基化产生长期影响
Davide Sacco,Paolo Brambilla,Luciano Calzari et al.
Davide Sacco et al.
Background: Prenatal exposure to dioxin, a known endocrine disruptor, after the Seveso accident of 1976 has been associated with thyroid dysfunction, metabolic syndrome and semen quality reduction. Experimental exposure t...
An overview of insulin resistance: from molecular mechanisms to medical interventions [0.03%]
胰岛素抵抗概论——从中枢机制到医学干预措施
Sristi Dey,Promit S Roy,Angel Mendonca et al.
Sristi Dey et al.
Insulin resistance (IR) is a condition where insulin-targeted tissues (muscle, liver, and adipose tissue) fail to normally respond to insulin action, leading to impaired insulin signaling and hyperglycemia. It is common in individuals with ...
Gianni Testino
Gianni Testino
Sexual and reproductive effects of androgenic anabolic steroids abuse: a clinical challenge in male and female cisgender and transgender individuals [0.03%]
雄激素促蛋白同化制剂滥用的性及生殖影响：男性和女性顺性别及跨性别个体中的临床挑战
Cristina Antinozzi,Luigi DI Luigi
Cristina Antinozzi
Currently, worldwide millions of individuals, athletes, and non-athletes, of different ages and probably of all social genders (cisgender males and females, male to female (MtF) and female to male (FtM) transgenders, etc.), are current or f...
Antonio Ríos,Iñaki Amunategui,José Ruiz Pardo et al.
Antonio Ríos et al.
Background: Papillary thyroid carcinoma (PTC) has classically been considered a sporadic carcinoma. However, a subgroup with familial clustering has been observed, which appears to present a poorer prognosis than the spor...
Efficacy and safety of oral semaglutide as add-on therapy in poorly controlled type 2 diabetes on background SGLT2 inhibitors: a real-world, multi-center, retrospective, observational study (RYS2) [0.03%]
口服司美格鲁肽作为二线药物治疗二甲双胍和SGLT-2抑制剂控制不佳的2型糖尿病患者的有效性和安全性：一项真实世界、多中心、回顾性、观察性研究（RYSTON 2）
Maria E Malighetti,Fabio Vescini,Maria Carpentieri et al.
Maria E Malighetti et al.
Background: Treatment of type 2 diabetes mellitus (T2DM) relies on diverse glucose-lowering medications, championing sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists as viab...
Association between serum uric acid and abdominal fat distribution quantified by computed tomography in Korean men: a single center study of 5144 cases [0.03%]
韩国男性血清尿酸与腹部脂肪分布量化之间的关系：一项关于5144例的单中心研究
Sungwon Ko,Su-Jin Choi,Young-Jee Jeon et al.
Sungwon Ko et al.
Background: Serum uric acid (UA), the end product of purine metabolism, has been implicated in metabolic and cardiovascular diseases. While obesity, particularly visceral fat accumulation, is related with hyperuricemia, l...