Giulia Guarino,Renata Bracale,Martina Ingrosso et al.
Giulia Guarino et al.
Impact of hypoglycemic agents on glycemic control and cognitive decline in older adults with type 2 diabetes: real-world evidence on glucagon like peptide 1 receptor agonists [0.03%]
降糖药物对老年2型糖尿病患者血糖控制和认知功能下降影响的现实世界证据——以胰高血糖素样肽-1受体激动剂为例
Benedetta DI Marzio,Giulia Gasparini,Andrea Ambrosio et al.
Benedetta DI Marzio et al.
Background: Type 2 diabetes mellitus (T2DM) is frequently associated with cognitive decline in the older population. Although optimal glycemic control is known to be essential for disease management, the impact of hypogly...
Real-time continuous glucose monitoring with subcutaneously inserted sensor correlates better than subcutaneously implantable sensor with glycated hemoglobin, glycated albumin and fructosamine [0.03%]
皮下植入传感器的实时连续血糖监测比皮下可植入传感器有更好的糖化血红蛋白、糖化白蛋白及果糖胺检测效果
Sanja Medenica,Roberto Negro,Djordje Popovic et al.
Sanja Medenica et al.
Background: Real-time continuous glucose monitoring (RT-CGM) is widely used in patients with type 1 diabetes (T1D) to improve glycemic control by reducing postprandial glucose peaks and hypoglycemic episodes. In addition,...
Meenakshi R Yathindra,Ayush Bhattacharjee,Nikhil Pundir et al.
Meenakshi R Yathindra et al.
Survodutide represents an innovative approach to obesity management and metabolic-associated fatty liver disease (MAFLD). These conditions, often closely linked with type 2 diabetes (T2DM) and cardiovascular diseases, demand effective treat...
Amylin role in glucose homeostasis and β-cell function: a robust justification [0.03%]
关于胰血糖素肽(GLP-1)在葡萄糖稳态及β细胞功能中的作用：充分的证据
Suad H Almasoudi,Hayder M Al-Kuraishy,Ali I Al-Gareeb et al.
Suad H Almasoudi et al.
Amylin is a peptide hormone co-secreted with insulin from pancreatic β-cells that plays a crucial role in glucose homeostasis. Amylin by inhibiting glucagon secretion, slowing gastric emptying, and reducing food intake improves blood gluco...
Effects of testosterone undecanoate as add-on therapy in obese hypogonadal men that are late responders to tirzepatide: a pilot study [0.03%]
十一酸睾酮作为肥胖性性腺功能减退症晚期患者的附加疗法对曲前列尼尔的影响：一项试点研究
Giuseppe Seminara,Marco Leuzzi,Leonardo Meduri et al.
Giuseppe Seminara et al.
Background: Male obesity-associated hypogonadism promotes a vicious cycle of sarcopenic obesity and increased cardiometabolic risk. Although tirzepatide is highly effective for weight loss, a subset of "late responders" h...
Gut microbiota and metabolic syndrome in postmenopausal women: a narrative review of mechanisms and dietary recommendations [0.03%]
绝经后女性肠道菌群和代谢综合征的机制及膳食建议综述
Sebastián Chapela,Julieta Locatelli,Melannie Toral-Noristz et al.
Sebastián Chapela et al.
Menopause brings a series of endocrine changes that significantly increase the risk of developing metabolic syndrome (MetS), a condition characterized by central obesity, dyslipidemia, hypertension, and insulin resistance. In this context, ...
Role of microRNA in type 1 diabetes pathogenesis and their therapeutic potential [0.03%]
微小核糖核酸在1型糖尿病发病机制中的作用及其治疗潜能
Manar F Atoum,Ala&#x; S Almehsen,Dalia A Alowaisy
Manar F Atoum
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreatic islets, resulting in complete insulin deficiency. The pathogenesis of T1D is multifactorial and includes ...
Dioxin, an endocrine disruptor, induces long term effects on DNA methylation in men after in-utero exposure [0.03%]
孕期接触二恶英的内分泌干扰物对男性DNA甲基化产生长期影响
Davide Sacco,Paolo Brambilla,Luciano Calzari et al.
Davide Sacco et al.
Background: Prenatal exposure to dioxin, a known endocrine disruptor, after the Seveso accident of 1976 has been associated with thyroid dysfunction, metabolic syndrome and semen quality reduction. Experimental exposure t...
An overview of insulin resistance: from molecular mechanisms to medical interventions [0.03%]
胰岛素抵抗概论——从中枢机制到医学干预措施
Sristi Dey,Promit S Roy,Angel Mendonca et al.
Sristi Dey et al.
Insulin resistance (IR) is a condition where insulin-targeted tissues (muscle, liver, and adipose tissue) fail to normally respond to insulin action, leading to impaired insulin signaling and hyperglycemia. It is common in individuals with ...