AQP4-AS1 Can Regulate the Expression of Ferroptosis-Related Regulator ALOX15 through Competitive Binding with miR-4476 in Lung Adenocarcinoma [0.03%]
AQP4-AS1通过与miR-4476竞争性结合调控肺腺癌铁死亡相关调节因子ALOX15表达
Lin Du,Geng Xu,Xiuqiang Zhang et al.
Lin Du et al.
Background The AQP4-AS1/miR-4476-ALOX15 regulatory axis was discovered in previous studies. We aimed to investigate the regulatory mechanism of the ferroptosis-related regulator ALOX15 by AQP4-AS1 and miR-4476 in lung adenocarcinoma (LUAD) ...
Analyzing Cell-free Genomic DNA in Spent Culture Media: Noninvasive Insight into the Blastocysts [0.03%]
分析培养基上清中的无细胞基因组DNA：对囊胚的非侵入性观察方法
Siddhartha Shankar Layek,Shrushti Kanani,Shilpa Doultani et al.
Siddhartha Shankar Layek et al.
A commonly accepted standard protocol for noninvasive techniques for the genetic evaluation of an embryo remains elusive due to inconclusiveness regarding the volume of spent media to be acquired and the possibility of acquiring the same fo...
ABO Blood Type and Urinary Bladder Cancer: Phenotype, Genotype, Allelic Association with a Clinical or Histological Stage and Recurrence Rate [0.03%]
ABO血型与尿路上皮癌的表型、基因型及等位基因多态性与临床病理分期和复发率的关系
Ivan Milas,Željko Kaštelan,Jószef Petrik et al.
Ivan Milas et al.
Background Previous research on connection between the ABO blood group and bladder cancer has been based on determining the ABO phenotype. This specific research is extended to the molecular level, providing more information about particula...
46 XX Ovotesticular Disorder of Sex Development with Gonadotropin-Releasing Hormone Receptor, Autosomal Recessive Heterozygous Missense Mutation and Autosomal Dominant Heterozygous Missense Mutation of the PROKR2 Gene: A Case Report [0.03%]
PROKR2基因垂体生殖素释放激素受体常染色体隐性错义突变和常染色体显性错义突变46XX卵巢睾丸性发育障碍病例报告
Francesca Peranzoni,Roberto De Castro,Emilio Merlini et al.
Francesca Peranzoni et al.
True hermaphroditism is a disorder of sex development (DSD), accounting for less than 5% of all DSD cases, defined by the simultaneous presence of testicular tissue and ovarian tissue in the same individual. In the reported case, the patien...
Recurrent Cerebral Venous Sinus Thrombosis Occurred in an Acute Lymphoblastic Leukemia Child with Mutated Lipoprotein Lipase Gene during Asparaginase Therapy [0.03%]
天门冬酰胺酶治疗期间因LPL基因突变发生急性淋巴细胞白血病儿童反复出现颅内静脉窦血栓形成
Shiyuan Wang,Jun Li,Ying Li et al.
Shiyuan Wang et al.
Cerebral venous sinus thrombosis (CVST) and hyperlipidemia are severe complications of L-Asparaginase (L-Asp) during the treatment of B-cell acute lymphoblastic leukemia (B-ALL). Herein, we reported a 9-year-old B-ALL boy who underwent abno...
Zongjin Li,Zhibo Han,Zhong-Chao Han
Zongjin Li
The Alarming Situation of Highly Pathogenic Avian Influenza Viruses in 2019-2023 [0.03%]
2019-2023年高致病性禽流感病毒的严峻形势
Zhiwei Zhang,Zhao Lei
Zhiwei Zhang
Avian influenza viruses (AIVs) have the potential to cause severe illness in wild birds, domestic poultry, and humans. The ongoing circulation of highly pathogenic avian influenza viruses (HPAIVs) has presented significant challenges to glo...
Comparing Genomic Profiles of ALK Fusion-Positive and ALK Fusion-Negative Nonsmall Cell Lung Cancer Patients [0.03%]
ALK融合阳性非小细胞肺癌与ALK融合阴性非小细胞肺癌的基因组特征比较分析
Wenchao Xia,Jing Yang,Hongbin Li et al.
Wenchao Xia et al.
Background Anaplastic lymphoma kinase ( ALK ) fusion events account for 3 to 7% of genetic alterations in patients with nonsmall cell lung cancer (NSCLC). This study aimed to explore the landscape of ALK fusion-positive and ALK fusion-negat...
Clinical and Molecular Characteristics of Megakaryocytes in Myelodysplastic Syndrome [0.03%]
骨髓增生异常综合征的巨核细胞的临床和分子特征分析
Fangxiu Luo,Jialu Zhao,Yubao Chen et al.
Fangxiu Luo et al.
Objective Myelodysplastic syndrome (MDS) is a malignant clonal disorder of hematopoietic stem cells which is characterized by morphologic dysplasia. However, the pathological characteristics of megakaryocytes (MKs) in MDS patients with gene...