Utility of KRAS Gene and Clinicopathological Features in the Assessment of the Risk of Type 2 Diabetes in the Etiology of Colon Cancer [0.03%]
KRAS基因和临床病理特征在评估结肠癌发病机制中2型糖尿病风险的应用
Wedad Saeed Al-Qahtani,Ebtesam Al-Olayan,Fatimah Gh Albani et al.
Wedad Saeed Al-Qahtani et al.
Background Cancer and diabetes have a tremendous impact on health globally. This study aimed to evaluate the KRAS gene in colon cancer tissues obtained from patients with type 2 diabetes mellitus (T2DM). Materials and Methods Data from 315 ...
Xiaojuan Wang,Na Li,Wei Li et al.
Xiaojuan Wang et al.
Adverse stress influences the normal growth and development of plants. With the development of molecular biology technology, understanding the molecular mechanism of plants in response to adverse stress has gradually become an important top...
CRISPLD2 Gene Polymorphisms with Nonsyndromic Cleft Lip Palate in Indian Population [0.03%]
CRISPLD2基因多态性与印度人群中非综合征型唇裂 palate的关系
Praveen Kumar Neela,Srinivas Reddy Gosla,Akhter Husain et al.
Praveen Kumar Neela et al.
Cleft lip palate (CLP) is one of the common congenital anomalies with multifactorial etiology. Many genes are associated with its etiology. In one of the studies CRISPLD2 gene polymorphisms rs1546124, rs4783099, and rs16974880 were reported...
The Clinical Effectiveness of Preimplantation Genetic Diagnosis for Chromosomal Translocation Carriers: A Meta-analysis [0.03%]
移植前遗传学诊断在染色体易位携带者中的临床效果：一项荟萃分析
Manijeh Mahdavi,Seyedeh M Sharafi,Seyede S Daniali et al.
Manijeh Mahdavi et al.
Published data on the relationship between pregnancy outcomes of preimplantation genetic diagnosis (PGD) in translocation carriers have implicated inconclusive results. To identify potentially eligible reports, an electronic search was cond...
Meta-Analysis on the Association of C-Reactive Protein Polymorphisms with Metabolic Syndrome [0.03%]
C反应蛋白基因多态性与代谢综合征关系的meta分析
Seyedeh Maryam Sharafi,Manijeh Mahdavi,Roya Riahi et al.
Seyedeh Maryam Sharafi et al.
Polymorphisms in the C-reactive protein (CRP) genes might have crucial role in the development of metabolic syndrome (MetS). In the current comprehensive meta-analyses, we aim to provide a quantitative assessment of the association between ...
Cansu Aydin,Rasime Kalkan
Cansu Aydin
Cancer can be identified as an uncontrolled growth and reproduction of cell. Accumulation of genetic aberrations (mutations of oncogenes and tumor-suppressor genes and epigenetic modifications) is one of the characteristics of cancer cell. ...
Oncogenic KRAS Drives Metabolic Vulnerabilities by Directly Regulating Metabolic Enzymes in Cancer [0.03%]
致癌KRAS通过直接调节癌细胞中的代谢酶来驱动代谢脆弱性
Liyi Zhang
Liyi Zhang
Metabolic reprogramming, such as enhanced aerobic glycolysis, allows cancer cells to maintain viability and promote proliferation. It is one of the major consequences of oncogenic mutations. KRAS is the most frequently mutated oncogene in h...