Cansu Aydin,Rasime Kalkan
Cansu Aydin
Cancer can be identified as an uncontrolled growth and reproduction of cell. Accumulation of genetic aberrations (mutations of oncogenes and tumor-suppressor genes and epigenetic modifications) is one of the characteristics of cancer cell. ...
Oncogenic KRAS Drives Metabolic Vulnerabilities by Directly Regulating Metabolic Enzymes in Cancer [0.03%]
致癌KRAS通过直接调节癌细胞中的代谢酶来驱动代谢脆弱性
Liyi Zhang
Liyi Zhang
Metabolic reprogramming, such as enhanced aerobic glycolysis, allows cancer cells to maintain viability and promote proliferation. It is one of the major consequences of oncogenic mutations. KRAS is the most frequently mutated oncogene in h...