Genetic Variants and Drug Efficacy in Tuberculosis: A Step toward Personalized Therapy [0.03%]
结核病的遗传变异和药物疗效：迈向个性化治疗的第一步
Almas Khan,Mohammad Abbas,Sushma Verma et al.
Almas Khan et al.
Tuberculosis (TB) continues to be a major infectious disease affecting individuals worldwide. Current TB treatment strategy recommends the standard short-course chemotherapy regimen containing first-line drug, i.e., isoniazid, rifampicin, p...
Molecular Detection of blaOXA -type Carbapenemase Genes and Antimicrobial Resistance Patterns among Clinical Isolates of Acinetobacter baumannii [0.03%]
分子检测β-内酰胺酶基因和临床鲍曼不动杆菌分离株的抗菌模式(pattern应为“模式”)
Maghsoud Kafshnouchi,Marzieh Safari,Amir Khodavirdipour et al.
Maghsoud Kafshnouchi et al.
Acinetobacter baumannii is a bacterium found in most places, especially in clinics and hospitals, and an important agent of nosocomial infections. The presence of class D enzymes such as OXA-type carbapenemases in A. baumannii is proven to ...
Analysis of Genetic Variations in Connexin 26 ( GJB2 ) Gene among Nonsyndromic Hearing Impairment: Familial Study [0.03%]
GJB2基因在非综合征听力损失中的遗传变异分析：家系研究
Smita Hegde,Rajat Hegde,Suyamindra S Kulkarni et al.
Smita Hegde et al.
Objective The goal of this research was to investigate the gap junction beta 2 ( GJB2 ) gene mutations associated with nonsyndromic hearing loss individuals in North Karnataka, India. Materials and Methods For this study, patients with sens...
A Case of Geroderma Osteodysplasticum Syndrome: Unique Clinical Findings [0.03%]
一例少见疾病—硬化骨皮肤综合征患者的临床特征分析
Maha Alotaibi,Deema Aldhubaiban,Ahmed Alasmari et al.
Maha Alotaibi et al.
Geroderma osteodysplasticum (GO; MIM 231070) is characterized by a typical progeroid facial appearance, wrinkled, lax skin, joint laxity, skeletal abnormalities with variable degree of osteopenia, frequent fractures, scoliosis, bowed long b...
Phenotype from SAMD9 Mutation at 7p21.2 Appears Attenuated by Novel Compound Heterozygous Variants at RUNX2 and SALL1 [0.03%]
位于7p21.2的SAMD9突变表型似乎被RUNX2和SALL1的新杂合化合物变异削弱
E Scott Sills,Samuel H Wood
E Scott Sills
Sterile α motif domain-containing protein 9 (SAMD9) is a regulatory protein centrally involved in cell proliferation and apoptosis. Mapped to 7p21.2, variants in SAMD9 have been reported in
CD24 + MDSC-DCs Induced by CCL5-Deficiency Showed Improved Antitumor Activity as Tumor Vaccines [0.03%]
CCL5缺陷诱导的CD24+MDSC-DC肿瘤疫苗展示出更强的抗肿瘤活性
Lei Huang,Zequn Ding,Yan Zhang
Lei Huang
Background Dendritic cell (DC) tumor vaccine has been extensively utilized in preclinical and clinical studies; however, this technique has encountered many difficulties, particularly in late-stage tumor patients. For those, ex vivo-induced...
Ayca Kocaaga,Mustafa Kocaaga
Ayca Kocaaga
Psoriasis is an erythematous-squamous dermatosis with a polygenic inheritance history. Both environmental and genetic factors play a role in the etiology of the disease. Over the past two decades, numerous linkage analyzes and genome-wide a...
Evaluation of Utilizing the Distinct Genes as Predictive Biomarkers in Late-Onset Alzheimer's Disease [0.03%]
用于评估独特基因作为预测生物标志物在晚发性阿尔茨海默病中的作用
Sercan Kenanoglu,Nefise Kandemir,Hilal Akalin et al.
Sercan Kenanoglu et al.
Alzheimer's disease (AD) is a neurodegenerative disease that is characterized by a devastating decline in cognitive activities among all types of dementia, and it severely affects the quality of life. Late-onset AD (LOAD) occurs after the a...