Efficacy and Safety of Hypomethylating Agents in Chronic Myelomonocytic Leukemia: A Single-Arm Meta-analysis [0.03%]
低甲基化药物治疗慢性粒单细胞白血病疗效和安全性的单臂 meta 分析
Xinhui Zheng,Liwei Lv,Xiangjun Li et al.
Xinhui Zheng et al.
Background Chronic myelomonocytic leukemia (CMML) is a myeloid neoplasm with features of the myelodysplastic syndromes (MDSs) and myeloproliferative neoplasm presenting with peripheral blood monocytosis and an inherent risk for transformati...
A Computational Data Mining Strategy to Identify the Common Genetic Markers of Temporomandibular Joint Disorders and Osteoarthritis [0.03%]
用于识别颞下颌关节病和骨关节炎的共有遗传标志物的计算数据挖掘策略
Vijayashree Priyadharsini Jayaseelan,Paramasivam Arumugam
Vijayashree Priyadharsini Jayaseelan
Statement of Problem Prosthodontic planning in patients with temporomandibular joint disorders (TMDs) is a challenge for the clinicians. Purpose A differential biomarker identification could aid in developing methods for early detection and...
Comparison of Bioinformatics Approaches for Fetal Microdeletions and Monogenic Variations Estimation in Non-invasive Prenatal Testing [0.03%]
无创产前检测中生物信息学方法评估胎儿拷贝数微缺失和单基因变异的比较研究
Lizzy Teleboshe Paul,Mahmut Cerkez Ergoren
Lizzy Teleboshe Paul
Prenatal testing provides crucial information about the health status of fetuses as well as recommending better treatment. For the past decades, prenatal testing using chorionic villus sampling and amniocentesis were the two majorly used fo...
Genotype-Phenotype Correlations for Putative Haploinsufficient Genes in Deletions of 6q26-q27: Report of Eight Patients and Review of Literature [0.03%]
六号染色体短臂末端缺失中假定的单剂量基因的基因型表型相关性：八名患者报告及文献复习
Xiaolei Xie,Hongyan Chai,Autumn DiAdamo et al.
Xiaolei Xie et al.
Background Cytogenomic analyses have been used to detect pathogenic copy number variants. Patients with deletions at 6q26-q27 present variable clinical features. We reported clinical and cytogenomic findings of eight unrelated patients with...
Aliya A Rizvi,Mohammad Abbas,Sushma Verma et al.
Aliya A Rizvi et al.
Diabetes has become a pandemic as the number of diabetic people continues to rise globally. Being a heterogeneous disease, it has different manifestations and associated complications in different individuals like diabetic nephropathy, neur...
Genetic Variants in Interleukin-10 Gene Association with Susceptibility and Cervical Cancer Development: A Case Control Study [0.03%]
关于白细胞介素10基因多态性与宫颈癌易感性和发病关系的病例对照研究
Pushpendra D Pratap,Syed Tasleem Raza,Ghazala Zaidi et al.
Pushpendra D Pratap et al.
Objectives Cervical cancer (CC) is one of the most destructive disease caused by persistent HPV infection which affects women worldwide, especially in developing countries. The genetic basis of host immune response especially cytokine funct...
Mahamad Irfanulla Khan,Nadeem Ahmed,Praveen Kumar Neela et al.
Mahamad Irfanulla Khan et al.
The development of tooth is a highly complex procedure and mastered by specific genetic programs. Genetic alterations, environmental factors, and developmental timing can disturb the execution of these programs, and result in various dental...
Nucleotide Sequence Sharing between the Human Genome and Primers for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Detection [0.03%]
针对严重急性呼吸系统综合症冠状病毒Ⅱ型（SARS-CoV-2）检测引物与人类基因组核酸序列共享性分析
Darja Kanduc
Darja Kanduc
This study shows that oligonucleotide sequences are shared between the human genome and primers that have been proposed/used for SARS-CoV-2 detection by polymerase chain reaction (PCR). The high level of sharing (namely, up to 19mer with a ...
Presentation of an Infant with Chromosome 18p Deletion Syndrome and Asymmetric Septal Hypertrophy [0.03%]
染色体18p缺失综合征并室间隔不对称肥厚症婴儿一例及其父亲携带者的临床分析
Ayca Kocaaga,Sevgi Yimenicioglu
Ayca Kocaaga
The frequency of 18p deletion syndrome is estimated to be ∼1/50,000 live births and is more commonly associated with certain clinical features including short stature, intellectual disability, and facial dysmorphism. Physical examination o...