Himanshu Singh,Magesh Kumar,Himanshu Kanungo
Himanshu Singh
Acute myeloid leukemia (AML) is an immensely heterogeneous disease characterized by the clonal growth of promyelocytes or myeloblasts in bone marrow as well as in peripheral blood or tissue. Enhancement in the knowledge of the molecular bio...
Association of Interleukin-1 Receptor Antagonist ( IL-1RA ) Gene Polymorphism with Community-Acquired Pneumonia in North Indian Children: A Case-Control Study [0.03%]
印度北部儿童社区获得性肺炎与白细胞介素-1受体拮抗剂(IL-1RA)基因多态性的病例对照研究
Neha Verma,Shally Awasthi,Anuj K Pandey et al.
Neha Verma et al.
Background Community-acquired pneumonia (CAP) is the leading cause of death in children < 5 years of age. The primary objective of the study was to assess the association of IL-1RA gene polymorphism in children aged 2 to 59 months with CAP ...
The Frequency of SMN1, SMN2 Copy Numbers in 246 Turkish Cases Analyzed with MLPA Method [0.03%]
MLPA方法分析的246例土耳其脊髓性肌萎缩症患者SMN1、SMN2拷贝数分布
Sinem Yalcintepe,Yasemin Karal,Selma Demir et al.
Sinem Yalcintepe et al.
This study aimed to define the copy numbers of SMN1 and SMN2 genes and the diagnosis rate and carrier frequency of spinal muscular atrophy (SMA) in the Thrace region of Turkey. In this study, the frequency of deletions in exons 7 and 8 in t...
PMM2 -CDG T237M Mutation in a Patient with Cerebral Palsy-Like Phenotypes Reported from South India [0.03%]
携带PMM2基因T237M突变的共济失调毛细血管扩张样贫血综合征病例报告
N Sreedevi,N Swapna,Santosh Maruthy et al.
N Sreedevi et al.
Congenital disorder of glycosylation (CDG) is an autosomal recessively inherited disorder. Hypotonia, stroke-like episodes, and peripheral neuropathy are also associated with the condition that typically develops during infancy. The patient...
Role of Molecular Targeted Therapeutic Drugs in Treatment of Breast Cancer: A Review Article [0.03%]
分子靶向治疗药物在乳腺癌治疗中的作用：综述文章
Himanshu Singh
Himanshu Singh
Breast cancer is a multifactor, multistage, and heterogeneous disease. Systemic treatment of breast cancer has changed significantly over the last decade. With a better knowledge of the pathogenesis, researchers and scientists have discover...
Athanasios Michas,Basileios Michas,Anastasios Tsitsibis et al.
Athanasios Michas et al.
Early detection of urothelial cancer offers the potential for effective and successful treatment. Despite previous efforts, currently, there is not a well-validated, recommended screening program in any country. This integrative, literature...
Efficacy and Safety Analysis of Combination Therapy Consisting of Intravenous Immunoglobulin and Corticosteroids versus Respective Monotherapies in the Treatment of Relapsed ITP in Adults [0.03%]
成人ITP复发患者免疫球蛋白与糖皮质激素联合治疗疗效及安全性的 meta 分析
Lijun Fang,Jing Sun,Yongqiang Zhao et al.
Lijun Fang et al.
Objective In this study, we aimed to evaluate the efficacy and safety of combination therapy, consisting of intravenous immunoglobulin (IVIg) and corticosteroids, in comparison to respective monotherapies in the treatment of relapsed immune...
Enabling Real-World Data to Accelerate the Development of Innovative Cancer Biomarkers [0.03%]
释放真实世界数据在创新癌症生物标志物开发中的潜能
Chen Yeh
Chen Yeh
The molecular diagnostics industry has historically relied on sanitized clinical trials and commoditized data sources to inform its biomarker discovery and validation process-an under-substantiated approach that was ultra-expensive, resourc...
Darja Kanduc
Darja Kanduc
Background and Aim Immune response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in newborns and children after prophylactic immunization is currently a relevant research topic. The present study analyzes the issue by...
NGS-Panel Diagnosis Developed for the Differential Diagnosis of Idiopathic Toe Walking and Its Application for the Investigation of Possible Genetic Causes for the Gait Anomaly [0.03%]
用于特发性踮脚走路的鉴别诊断的下一代测序（NGS）基因检测开发及其在研究步态异常的可能遗传原因方面的应用
David Pomarino,Anna Emelina,Jens Heidrich et al.
David Pomarino et al.
Idiopathic toe walking (ITW) describes a condition affecting approximately 4.5% of children. Toe walking is an accompanying symptom for many hereditary disorders. This retrospective study uses next-generation sequencing-panel-diagnosis to i...