Shared Genes and Molecular Mechanisms between Nonalcoholic Fatty Liver Disease and Hepatocellular Carcinoma Established by WGCNA Analysis [0.03%]
基于WGCNA分析建立的非酒精性脂肪肝病与肝细胞癌共有的基因和分子机制研究
Juan He,Xin Zhang,Xi Chen et al.
Juan He et al.
Background Hepatocellular carcinoma (HCC) is one of the leading causes of death from cancer worldwide. The histopathological features, risk factors, and prognosis of HCC caused by nonalcoholic fatty liver disease (NAFLD) appear to be signif...
BL-MOL-AR Project, Preliminary Results about Liquid Biopsy: Molecular Approach Experience and Research Activity in Oncological Settings [0.03%]
BL-MOL-AR项目在肿瘤科医疗环境中关于液体活检的分子方法的经验和研究活动的初步结果
Alessandro Pancrazzi,Francesco Bloise,Alice Moncada et al.
Alessandro Pancrazzi et al.
Background Liquid biopsy is mainly used to identify tumor cells in pulmonary neoplasms. It is more often used in research than in clinical practice. The BL-MOL-AR study aims to investigate the efficacy of next-generation sequencing (NGS) an...
Strokelike Episodes in PMM-2 Carriers Differ from Those in Mitochondrial Disorders [0.03%]
PMM2空泡病的脑卒中样发作与线粒体病不同
Josef Finsterer
Josef Finsterer
Epigenetics of Hypogonadotropic Hypogonadism: Molecular Mimicry between Severe Acute Respiratory Syndrome Coronavirus 2 and KISSR [0.03%]
下丘脑性性腺功能减退的表观遗传学：严重急性呼吸综合征冠状病毒2与KISSR之间的分子模拟关系
Darja Kanduc
Darja Kanduc
This study analyzed KISS1 and its receptor KISSR for peptide sharing with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It was found that SARS-CoV-2 shares numerous minimal immune pentapeptide determinants with KISSR only. T...
Himanshu Singh,Magesh Kumar,Himanshu Kanungo
Himanshu Singh
Acute myeloid leukemia (AML) is an immensely heterogeneous disease characterized by the clonal growth of promyelocytes or myeloblasts in bone marrow as well as in peripheral blood or tissue. Enhancement in the knowledge of the molecular bio...
Association of Interleukin-1 Receptor Antagonist ( IL-1RA ) Gene Polymorphism with Community-Acquired Pneumonia in North Indian Children: A Case-Control Study [0.03%]
印度北部儿童社区获得性肺炎与白细胞介素-1受体拮抗剂(IL-1RA)基因多态性的病例对照研究
Neha Verma,Shally Awasthi,Anuj K Pandey et al.
Neha Verma et al.
Background Community-acquired pneumonia (CAP) is the leading cause of death in children < 5 years of age. The primary objective of the study was to assess the association of IL-1RA gene polymorphism in children aged 2 to 59 months with CAP ...
The Frequency of SMN1, SMN2 Copy Numbers in 246 Turkish Cases Analyzed with MLPA Method [0.03%]
MLPA方法分析的246例土耳其脊髓性肌萎缩症患者SMN1、SMN2拷贝数分布
Sinem Yalcintepe,Yasemin Karal,Selma Demir et al.
Sinem Yalcintepe et al.
This study aimed to define the copy numbers of SMN1 and SMN2 genes and the diagnosis rate and carrier frequency of spinal muscular atrophy (SMA) in the Thrace region of Turkey. In this study, the frequency of deletions in exons 7 and 8 in t...
PMM2 -CDG T237M Mutation in a Patient with Cerebral Palsy-Like Phenotypes Reported from South India [0.03%]
携带PMM2基因T237M突变的共济失调毛细血管扩张样贫血综合征病例报告
N Sreedevi,N Swapna,Santosh Maruthy et al.
N Sreedevi et al.
Congenital disorder of glycosylation (CDG) is an autosomal recessively inherited disorder. Hypotonia, stroke-like episodes, and peripheral neuropathy are also associated with the condition that typically develops during infancy. The patient...
Role of Molecular Targeted Therapeutic Drugs in Treatment of Breast Cancer: A Review Article [0.03%]
分子靶向治疗药物在乳腺癌治疗中的作用：综述文章
Himanshu Singh
Himanshu Singh
Breast cancer is a multifactor, multistage, and heterogeneous disease. Systemic treatment of breast cancer has changed significantly over the last decade. With a better knowledge of the pathogenesis, researchers and scientists have discover...
Athanasios Michas,Basileios Michas,Anastasios Tsitsibis et al.
Athanasios Michas et al.
Early detection of urothelial cancer offers the potential for effective and successful treatment. Despite previous efforts, currently, there is not a well-validated, recommended screening program in any country. This integrative, literature...